The Molecular and Cellular Mechanisms of Carotenoids in Health and Disease
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: closed (31 December 2022) | Viewed by 6943
Special Issue Editors
2. Advanced Research Promotion Center, Health Sciences University of Hokkaido, 1757 Kanazawa, Ishikari-Tobetsu, Hokkaido 061-0293, Japan
Interests: fucoxanthin; carotenoid; dietary marine algae; cancer chemoprevention; animal model
Interests: cancer chemoprevention; animal model; translational research
Special Issues, Collections and Topics in MDPI journals
Interests: colorectal carcinogenesis; cancer chemoprevention; inflammatory bowel disease; ulcerative colitis; Crohn’s disease; animal model
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Carotenoids, a category of tetraterpenoids, are fat soluble yellow-orange pigments and widely distributed in daily foods such as vegetables, fruits, and macroalgae. Carotenoids are divided into carotenes and their oxygenated derivatives (xanthophylls) that contain lycopene, α-carotene, β-carotene, lutein, zeaxanthin, β-cryptoxanthin, violaxanthin, neoxanthin, and fucoxanthin. They have been identified as important phytochemicals possessing anticancer activities. To date, many epidemiological approaches have suggested that intake of foods containing carotenoids is associated with a reduction in the risk of a variety of human cancers. However, the preventive effects of carotenoids against cancers remain inconsistent. While the World Cancer Research Fund and American Institute for Cancer Research (WCRF/AICR) 2018 concludes that the evidence of cancer preventive effects of carotenoids-containing foods is “limited/suggestive”, promising outcomes against cancer development by carotenoids and/or foods containing carotenoids are being reported in human every day. In experimental animal model studies, carotenoid(s) administration has been reported to exert their chemopreventive and/or therapeutic potentials against various types of cancer through several mechanisms, including anti-inflammation, autophagy, apoptosis, anoikis, attenuations of core signal transduction and tumor microenvironment, and alteration of microbiota.
In future, it is possible that accumulation of more knowledge on the anti-cancer effects by carotenoids induces an upgrade to “probable” decrease in the risk of cancers.
This Special Issue invites original research, clinical studies, and/or reviews on the chemopreventive and therapeutic potentials of carotenoids in patients with cancer and in carcinogenic animal models.
Dr. Masaru Terasaki
Prof. Dr. Michihiro Mutoh
Dr. Takuji Tanaka
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- carotenoids
- cancer chemopreventive effects
- cancer therapeutic effects
- carcinogenic animal model
- translational research
- human interventional research
- cancer stem cells
- epithelial-mesenchymal transition
- tumor microenvironment
- immune regulation
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.