Special Issue "Cigarette Smoke and Pulmonary Disease"
Deadline for manuscript submissions: 30 December 2022 | Viewed by 33
Interests: respiratory diseases; cigarette smoke; bronchial epithelial cells; inflammation; immune response; lung cancer; pathophysiology
Cigarette smoke is a mixture of gas, vapor, and solid particles, and contains thousands of molecules, most of which are severely harmful to humans. Once cigarette smoke is in the respiratory tree, the airway epithelium is the first line of defense and activates repair mechanisms. The continuous insult impairs these internal defense mechanisms and leads to DNA, protein, and organelle damage, as well as to structural and morphological changes of the cells with the activation of a chronic inflammatory process, associated with the recruitment of immune cells, which could lead to a transformation in cancer cells or to the activation of senescent mechanisms.
Several studies have shown the involvement of cigarette smoke in the pathogenesis of several respiratory diseases (COPD, lung cancer, fibrosis, etc.), and for this reason cigarette smoke is considered the main risk factor for them, but not everything is known yet.
This Special Issue, titled “Cigarette smoke and respiratory diseases”, aims to collect original research or review articles focused on exploring new insights into molecular signaling networks involved in the pathogenesis of respiratory diseases related to cigarette smoke exposure.
Dr. Serena Di Vincenzo
Dr. Elisabetta Pace
Manuscript Submission Information
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- cigarette smoke
- respiratory diseases
- immune response