Alternative Nicotine Delivery Devices on Lung Health

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Physiology".

Deadline for manuscript submissions: closed (31 July 2022) | Viewed by 193

Special Issue Editor


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Guest Editor
Birmingham Acute Care Research Group, Institute of Inflammation and Ageing, University of Birmingham, Level 2 Queen Elizabeth Hospital Birmingham, Birmingham B15 2TH, UK
Interests: inflammation; ageing; pulmonary immunology; smoking-related disease; COPD; pneumonia
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Special Issue Information

Dear Colleagues, 

Smoking cessation is a difficult and often unsuccessful venture. Alternative nicotine delivery devices such as e-cigarettes and heat-not-burn devices represent a novel strategy for nicotine replacement therapies, which may hold greater efficacy and longer-term efficacy. Indeed, clinical trial evidence to date supports the prolonged usage of e-cigarettes initially used for tobacco cessation. These devices are less harmful than cigarette smoking, but we still lack an understanding of how much less harmful and what long-term effects these lower-harm devices may yet have on an e-cigarette user. Heat-not-burn devices hold even greater uncertainty—with much of the available evidence in their support provided by the manufactures, the need for more, independent research is clear.  

In this Special Issue, we hope to examine the following:

  1. Efficacy—are these devices truly more effective than pharmacological therapies and OTC alternatives? In the current varenicline hiatus, this may change the equation;
  2. What do we know about the effects of e-cigarettes/heat-not-burn on pulmonary health?
  3. Tobacco smoking causes significant systemic effects. What evidence do we have on the effects of these devices systemically?
  4. Based on the current evidence available, can we quantify the potential harm of short-term and long-term usage of a) e-cigarettes and b) heat-not-burn devices?

It is unlikely we will fully answer these questions, but perhaps by collating the evidence in this series, we can provide a more holistic view of these important issues so we can formulate a first estimate on a true cost–benefit analysis.

Dr. Aaron Scott
Guest Editor

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Keywords

  • e-cigarettes
  • heat-not-burn
  • toxicology
  • smoking cessation
  • reactive carbonyl species

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