Inflammation, Infection and Ageing of the Lung
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Immunology".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 290
Special Issue Editor
Interests: inflammation; ageing; pulmonary immunology; smoking-related disease; COPD; pneumonia
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We are pleased to invite you to contribute to this Special Issue, which aims to exmaine the importance of inflammation and ageing and their importance in lung diseases. We live in an ageing global community: whether regarded as a high or low-income country, every nation is now experiencing an increase in the proportion of their older population. WHO figures suggest that 1 in 6 people will be aged 60 over over by 2030. Age-related immune dysfunction makes older adults more at risk of chronic disease and puts older adults at a much greater intrinsic risk from infectious lung disease from bacterial or viral pathogens. This is of particular importance in the immune landscape of the lung, where the incidence of severe infection, such as community-acquired penumonia and sepsis, is asscoiated with much higher mortiality rates, both from initial infection and from secondary infections, a reality potentiated by the subsequent immunoparesis caused by the initial infectious event. Similarly acute exacerbations of Ccronic obstructive pulmonary disease are strongly associated with mortality, though this not necessarily directly caused by the initial infectious event. Ageing is a component in many chronic and infectious lung diseases and may be the underlying process which links seemingly disparate pathologies.
This Special Issue aims to explore how changes related to age contribute to increasing the risk and severity of inflammatory lung disease. Many lung diseases currently have no cure and there is a lack of fundamental understanding of their underlying biology. This Issue invites submissions which examine how age impacts pathology through exploration of potentially shared, underlying disease mechanisms.
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but is not limited to) manuscripts exploring the impact of age on the immune landscape and the impacts of this on chronic inflammatory lung diseases and infection.
We look forward to receiving your contributions.
Dr. Aaron Scott
Guest Editor
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- COPD
- CAP
- sepsis
- ARDS
- ageing
- immunosenescence
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