Mechanisms of Neuroendocrine Response to Stress in Insects

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Biochemistry and Molecular Biology".

Deadline for manuscript submissions: 31 December 2026 | Viewed by 116

Special Issue Editor


E-Mail Website1 Website2
Guest Editor
1. Department of Agricultural Science and Plant Protection, Mississippi State University, Starkville, MS 39762, USA
2. Department of Biochemistry, Nutrition and Health Promotion, Mississippi State University, Starkville, MS 39762, USA
Interests: toxicology; insect-plant interaction; xenobiotic metabolism
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Special Issue Information

Dear Colleagues,

Insects inhabit an extraordinary range of ecological niches and are continuously challenged by diverse biotic and abiotic stressors, including pathogens, parasites, predators, temperature extremes, desiccation, hypoxia, and anthropogenic chemicals. Their ability to survive and thrive under these pressures depends on highly integrated neuroendocrine mechanisms that coordinate physiological, behavioral, and metabolic responses. Over the past decade, advances in molecular biology, neurogenetics, and comparative physiology have revealed that insect neuroendocrine systems—particularly those involving neuropeptides, biogenic amines, and hormonal axes such as the insulin/IGF, ecdysteroid, and juvenile hormone pathways—play central roles in stress detection, signaling, and adaptation.

Despite these advances, the mechanistic links between environmental stressors and neuroendocrine regulation remain incompletely understood. Key questions persist regarding how insects sense and integrate multiple stress cues; how neuroendocrine circuits orchestrate cross‑talk between immunity, metabolism, and development; and how these pathways evolve across taxa with distinct ecological strategies. Understanding these processes is increasingly urgent as climate change, habitat alteration, and globalized agriculture intensify stress exposure and reshape insect population dynamics.

This Special Issue aims to bring together cutting‑edge research that elucidates the molecular, cellular, and systemic mechanisms underlying neuroendocrine regulation of stress responses in insects. We welcome studies spanning model and non‑model species, employing approaches from genomics and neurophysiology to behavioral ecology and evolutionary biology. By integrating diverse perspectives, this collection seeks to provide a holistic understanding of how neuroendocrine systems mediate resilience to environmental challenges, with implications for insect conservation, pest management, and the broader study of stress biology.

Prof. Dr. Natraj Krishnan
Guest Editor

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Keywords

  • neuroendocrine signaling
  • insect stress physiology
  • neuropeptides and hormones
  • biotic and abiotic stress
  • stress response pathways
  • environmental adaptation
  • insect neurobiology
  • hormonal regulation

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