Biology Enrichment of Radionuclides: New Development

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Toxicology".

Deadline for manuscript submissions: closed (1 September 2023) | Viewed by 1767

Special Issue Editors


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Guest Editor
Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health & Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China
Interests: enrichment; radionuclides; plants; animals; fungi; bacteria

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Guest Editor
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China
Interests: environmental pollution control and resource utilization research; low-temperature plasma application research

Special Issue Information

Dear Colleagues,

Radioactive pollution has become a very serious environmental problem today. For example, a large number of radionuclides leaked from the Fukushima accident in Japan have been retained in the environment for a long time. Radioactive pollution not only causes radiation to the environment (α,β,γ), but radionuclides can also enter the food chain through the biosphere, endangering human survival and health. Various kinds of radionuclides are considered important due to their interactions with biological tissues (plants, animals, fungi, bacteria). Therefore, it is pivotal to understand the migration and enrichment of radionuclides, as well as the relevant biological effects, particularly the corresponding molecular mechanisms and cell signal pathways involved in these biological processes.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: enrichment of radionuclides in plants, animals, fungi, and bacteria. We hope the papers in this Special Issue will be of high value to scientists working in the field of biology enrichment of radionuclides. We look forward to receiving your valuable papers in the upcoming months.

Dr. Wencheng Song
Prof. Dr. Dadong Shao
Guest Editors

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Keywords

  • enrichment
  • radionuclides
  • plants
  • animals
  • fungi
  • bacteria

Published Papers (1 paper)

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Research

12 pages, 2088 KiB  
Article
Transcriptome Analysis of the Immortal Human Keratinocyte HaCaT Cell Line Damaged by Tritiated Water
by Yan Zhang, Yuanyuan Zhou, Hui Wu, Zhuna Yan, Jinwu Chen and Wencheng Song
Biology 2023, 12(3), 405; https://doi.org/10.3390/biology12030405 - 3 Mar 2023
Viewed by 1524
Abstract
Radioactive elements, such as tritium, have been released into the ocean in large quantities as a result of the reactor leakage accident. In this study, an MTT assay demonstrated that the viability of HacaT cells decreased after tritiated water treatment. Bioinformatics analysis was [...] Read more.
Radioactive elements, such as tritium, have been released into the ocean in large quantities as a result of the reactor leakage accident. In this study, an MTT assay demonstrated that the viability of HacaT cells decreased after tritiated water treatment. Bioinformatics analysis was used to analyze gene changes in the HacaT cells. The sequencing results showed 267 significantly differentially expressed genes (DEGs), and GO enrichment analysis showed that the DEGs were mainly divided into three parts. The KEGG pathway analysis showed that the up-regulated DEGs were involved in Wnt and other pathways, while the down-regulated DEGs were involved in Jak–STAT and others. A Western blot assay was used to verify the parts of the sequencing results. This study was the first to explore the mechanism of tritiated water on HacaT cells using Transcriptome analysis. The results will provide a theoretical basis for the study of tritiated water hazard mechanisms. Full article
(This article belongs to the Special Issue Biology Enrichment of Radionuclides: New Development)
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