Skeletal Muscle Physiology in Health and Aging
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Physiology".
Deadline for manuscript submissions: 28 February 2027 | Viewed by 183
Special Issue Editor
Interests: skeletal muscle physiology; sarcopenia; muscle regeneration; physical exercise; aging; cellular senescence; brain-muscle axis; neurodegeneration
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Skeletal muscle is a metabolically active tissue whose structural and functional integrity depends on the balance between protein synthesis and degradation, mitochondrial metabolism and cell regeneration. Under physiological conditions, various stimuli, including physical exercise, nutritional status and signals from other tissues, modulate these processes, preserving muscle mass, contractile capacity and adaptive plasticity. In this context, the gut-muscle axis and the gut microbiota emerge as relevant systemic regulators, influencing energy metabolism, inflammatory processes and the adaptive capacity of muscle tissue.
However, with aging, the progressive dysregulation of these mechanisms compromises muscle function, promoting atrophy, sarcopenia and the accumulation of senescent cells. Alterations in the tissue microenvironment, chronic inflammation and changes in inter-organ crosstalk further contribute to functional decline, reducing muscle adaptive plasticity and body homeostasis. Undoubtedly, understanding the molecular and cellular basis of these processes is essential for identifying intervention strategies aimed at preserving muscle function and promoting healthy aging.
This Special Issue, Skeletal Muscle Physiology in Health and Aging, aims to collect contributions that explore the mechanisms underlying muscle physiology in both healthy conditions and during aging, including original articles and reviews focused on the physiological adaptations of skeletal muscle, nutritional modulation, the role of the gut microbiota, cellular senescence and inter-organ communication.
We look forward to receiving your contributions.
Dr. Roberto Bonanni
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- skeletal muscle
- muscle physiology
- healthy
- aging
- nutrition
- senescence
- gut microbiota
- crosstalk
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
