Stem Cells in Experimental Medicine
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cell Biology".
Deadline for manuscript submissions: 31 May 2025 | Viewed by 4735
Special Issue Editors
Interests: skin stem cells; AAV-mediated gene therapy
Special Issue Information
Dear Colleagues,
Stem cells possess the remarkable ability to self-renew and differentiate into functional cells, playing pivotal roles during organogenesis and in adults, where they continue to be responsible for repairing wounded tissues. The potential of exogenous stem cells (or their derived exosomes) to restore the function of damaged tissues, either through cell replacement or by secreting growth factors, holds great promise for therapeutic applications. The combination of stem cells with biodegradable materials further enhances the potential of stem-cell-based therapies. Stem-cell-derived organoids and induced pluripotent stem cells (iPSs) are widely used for disease modeling and drug screening.
Despite the significant progress in stem cell research, there remain numerous challenges, including expanding stem cells without losing stemness in vitro, enhancing the survival of transplanted stem cells within damaged tissues, and ensuring their integration into host tissue to function effectively. Investigating the molecular mechanisms of stem cell self-renewal and differentiation will further advance the translational research on stem cells.
This Special Issue aims to provide a platform for cutting-edge research addressing the challenge of stem cells in experimental medicine. I invite you to contribute your expertise; we welcome original manuscripts as well as reviews in these fields.
Prof. Dr. Xinhua Liao
Dr. Xusheng Wang
Guest Editor
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Keywords
- adult stem cells
- induced pluripotent stem cells (iPSs)
- embryonic stem cells
- progenitor cells
- stem-cell-derived organoids
- stem-cell-derived exosomes
- stem-cell-based therapy
- stem-cell-based disease modeling
- stem-cell-based tissue engineering
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