Applications of Biomaterials in Dental Medicine

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 1589

Special Issue Editor


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Guest Editor
Dipartimento Multidisciplinare di Specialità Medico-Chirurgiche e Odontoiatriche, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy
Interests: biomaterial; regenerative and reconstructive medicine; bone and tissue regeneration; implants; dental medicine

Special Issue Information

Dear Colleagues,

Dental medicine is a field that constantly evolves with the advances in technology and materials science. Biomaterials play a crucial role in modern dental practice, offering innovative solutions for various dental procedures and treatments. This Special Issue aims to highlight the diverse applications of biomaterials in dental medicine, showcasing the latest research and developments in the field.

From dental implants to orthodontic braces, biomaterials have revolutionized the way dental procedures are carried out, improving patient outcomes and enhancing treatment efficacy. The integration of biomaterials in dental medicine has also led to the development of new approaches for preventing and treating oral diseases, ultimately contributing to the overall oral health of individuals.

This Special Issue invites researchers and experts in the field of bioengineering to contribute their original research, reviews, and perspectives on the applications of biomaterials in dental medicine. By bringing together the latest advancements and insights, we aim to create a comprehensive resource that will inspire further innovation and progress in the field of dental biomaterials.

Dr. Alfredo De Rosa
Guest Editor

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Keywords

  • biomaterials
  • dental medicine
  • dental implants
  • orthodontics
  • oral health

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Published Papers (1 paper)

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Review

18 pages, 309 KiB  
Review
Next-Generation Biomaterials for Vital Pulp Therapy: Exploring Biological Properties and Dentin Regeneration Mechanisms
by Vidhyashree Rajasekar, Mohamed Mahmoud Abdalla, Mengyu Huang, Prasanna Neelakantan and Cynthia Kar Yung Yiu
Bioengineering 2025, 12(3), 248; https://doi.org/10.3390/bioengineering12030248 - 28 Feb 2025
Viewed by 1350
Abstract
The advancement of Vital Pulp Therapy (VPT) in dentistry has shown remarkable progress, with a focus on innovative materials and scaffolds to facilitate reparative dentin formation and tissue regeneration. A comprehensive search strategy was performed across PubMed, Scopus, and Web of Science using [...] Read more.
The advancement of Vital Pulp Therapy (VPT) in dentistry has shown remarkable progress, with a focus on innovative materials and scaffolds to facilitate reparative dentin formation and tissue regeneration. A comprehensive search strategy was performed across PubMed, Scopus, and Web of Science using keywords such as “vital pulp therapy”, “biomaterials”, “dentin regeneration”, and “growth factors”, with filters for English language studies published in the last 10 years. The inclusion criteria focused on in vitro, in vivo, and clinical studies evaluating traditional and next-generation biomaterials for pulp capping and tissue regeneration. Due to the limitations of calcium-based cements in tissue regeneration, next-generation biomaterials like gelatin, chitosan, alginate, platelet-rich fibrins (PRF), demineralized dentin matrix (DDM), self-assembling peptides, and DNA-based nanomaterials were explored for their enhanced biocompatibility, antibacterial properties, and regenerative potential. These biomaterials hold great potential in enhancing VPT outcomes, but further research is required to understand their efficacy and impact on dentin reparative properties. This review explores the mechanisms and properties of biomaterials in dentin tissue regeneration, emphasizing key features that enhance tissue regeneration. These features include biomaterial sources, physicochemical properties, and biological characteristics that support cells and functions. The discussion also covers the biomaterials’ capability to encapsulate growth factors for dentin repair. The development of innovative biomaterials and next-generation scaffold materials presents exciting opportunities for advancing VPT in dentistry, with the potential to improve clinical outcomes and promote tissue regeneration in a safe and effective manner. Full article
(This article belongs to the Special Issue Applications of Biomaterials in Dental Medicine)
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