Novel Biomaterial Designs and Strategies for Orthopaedic Surgery
A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".
Deadline for manuscript submissions: closed (1 October 2023) | Viewed by 4213
Special Issue Editors
Interests: bioprinting; tissue engineering; microfluidics; biomaterials; smart biomedical devices
Special Issues, Collections and Topics in MDPI journals
Interests: bone/cartilage tissue engineering; stem cell therapy; bioactive hydrogel
Interests: tissue engineering; immunomodulation; biomaterials; bone regeneration; stem cells
Interests: osteoporotic fracture; bone regeneration; sarcopenia; stem cells
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The musculoskeletal system is comprised of bones, muscles, cartilage, tendons, ligaments, joints, and other connective tissues that support and bind tissues and organs together, providing mechanical support and movement to the human body. Orthopaedic surgery holds the largest share of the organ transplantation market. While small bone defects can heal on their own, bone healing is significantly compromised with increasing defect size, aging, and other pathological conditions. The gold standard for treating critical-sized bone defects uses bone grafts, which are limited by an insufficient donor tissue supply and donor site morbidity. Tissue engineering offers an alternative strategy for bone repair using cells, biomaterials, and biological signals. As the gap between donors and transplantations needed becomes increasingly larger, there is a clear demand for advanced biomaterials and tissue engineering strategies to fill this insufficiency. Despite recent advances in the development of novel biomaterials and their fabrication techniques, clinically available biomaterials capable of completely replacing or restoring the functions of native tissues are yet to be developed.
This Special Issue of Bioengineering on “Novel Biomaterial Designs and Strategies for Orthopaedic Surgery” aims to, therefore, focus on compiling original research papers and comprehensive reviews dealing with cutting-edge discoveries and/or methodologies for the material design, development, and corresponding treatment strategies improving orthopaedic surgery. Topics of interest for this Special Issue include, but are not limited to, the following:
- The design and synthesis of novel biomaterials for musculoskeletal tissue regeneration;
- Novel biomaterials for musculoskeletal replacement or transplantation;
- Biomaterials for stem cell therapy in orthopaedic disorders;
- Fabrication strategies for novel biomaterials;
- The investigation of biomaterials concerning their mechanical properties and functions for orthopaedic purposes;
- Clinic-relevant large animal studies for functions of biomaterials for orthopaedic purposes;
- Biomaterial design or drug delivery strategies for immunomodulation in orthopaedic treatments.
All research areas are considered relevant as long as experimentations are the main study drivers.
Dr. Jiannan Li
Dr. Sien Lin
Dr. Ni Su
Dr. Ning Zhang
Guest Editors
Manuscript Submission Information
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Keywords
- biomaterials
- bioprinting
- tissue engineering
- hydrogels
- stem cells
- orthopaedic surgery
- bone regeneration