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Applied Sciences
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New Ultrasound Techniques—Applications in Internal Medicine
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New Ultrasound Techniques—Applications in Internal Medicine

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Biomedical Engineering".

Deadline for manuscript submissions: closed (20 May 2024) | Viewed by 5299

Special Issue Editor

Prof. Dr. Dana Stoian

E-Mail Website
Guest Editor
Department of Endocrinology, “Victor Babes” University of Medicine and Pharmacy, 300041 Timisoara, Romania
Interests: elastography; viscosity; contrast-enhanced ultrasound; multiparametric evaluation; thyroid disease; renal disease; liver fibrosis; hyperparathyroidism; endocrinology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We are pleased to invite you to contribute your recent research on the newest ultrasound applications, such as viscosity or the contrast-enhanced ultrasound technique, used in the diagnosis of liver fibrosis and diffuse thyroid disease, respectively, nodular pathology in the liver, thyroid or testes.

Currently, complementary applications to conventional ultrasounds are exceptional imaging techniques, using different advanced software. There is sufficient evidence regarding the successful contribution of elastography in different areas of internal medicine, such as the evaluation of liver fibrosis and risk stratification of thyroid and testicular nodules, which ultimately reduces the need for fine needle biopsies. Thus, new techniques have emerged, such as the novel viscosity evaluation and the contrast-enhanced ultrasonography, bringing new, additional data regarding the qualities of tissue, which impacts decision making in the medical environment.

From a clinical point of view, this Special Issue aims to provide information regarding the application of ultrasounds in decision-making processes.

In this Special Issue, original research articles and reviews are welcome. Research areas may include, but not limited to, the following:

  • Defining normal in visco technique;
  • Viscosity in diffuse thyroid disease;
  • Viscosity in diffuse liver disease;
  • Multiparametric ultrasound diagnosis of thyroid disease;
  • Multiparametric ultrasound diagnosis of parathyroid disease;
  • Multiparametric ultrasound diagnosis of renal disease;
  • Multiparametric ultrasound diagnosis of testicular pathology;
  • Clinical applications of CEUS.

We look forward to receiving your contributions.

Prof. Dr. Dana Stoian
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • elastography
  • viscosity
  • contrast-enhanced ultrasound
  • multiparametric evaluation
  • thyroid disease
  • renal disease
  • liver fibrosis
  • hyperparathyroidism

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Published Papers (2 papers)

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Research

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12 pages, 2594 KiB  
Article
Is Strain Elastography Useful in Diagnosing Chronic Autoimmune Thyroiditis in Children?
by Cristina Mihaela Cepeha, Corina Paul, Andreea Borlea, Renata Bende, Monica Simina Mihuta and Dana Stoian
Appl. Sci. 2022, 12(17), 8881; https://doi.org/10.3390/app12178881 - 4 Sep 2022
Cited by 2 | Viewed by 1926
Abstract
Strain elastography (SE) determines the level of tissue stiffness and thus helps in the diagnosis and differentiation of various pathologies. This paper aims to study the elastographic differences between healthy thyroid parenchyma and ones affected by chronic autoimmune thyroiditis (CAT) in children. We [...] Read more.
Strain elastography (SE) determines the level of tissue stiffness and thus helps in the diagnosis and differentiation of various pathologies. This paper aims to study the elastographic differences between healthy thyroid parenchyma and ones affected by chronic autoimmune thyroiditis (CAT) in children. We included in our study 52 children diagnosed with CAT and 22 children with no thyroid pathology. After clinic examination and biological tests, an ultrasound was performed followed by SE using a Hitachi Preirus machine with a 5–15 multi-frequency linear probe. The mean strain ratio (SR) values were significantly lower in the control group compared with the CAT group (0.68 ± 0.2 vs. 1.19 ± 0.25; p < 0.0001). A mean value above 0.9 was found predictive for CAT with 84.62% Sensitivity(Se), 95.45% Specificity (Sp), 97.8% Positive Predictive Value (PPV), 72.4% Negative Predictive Value (NPV), and area under receiver operating characteristic (AUROC), 0.9. No differences were found between the two thyroid lobes. Also, we found no differences between girls and boys. Out of the 52 children with CAT, 39 were on therapy with levothyroxine. No differences were found between SR values in preexisting hypothyroid cases compared to euthyroid cases (1.24 ± 0.26 vs. 1.18 ± 0.25; p = 0.4615). Our results show that SE is a useful examination technique of children diagnosed with CAT, in accordance with other studies conducted on adults. This study lays the foundation for elastographic examination among children. Full article
(This article belongs to the Special Issue New Ultrasound Techniques—Applications in Internal Medicine)
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Review

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13 pages, 1042 KiB  
Review
Artificial Intelligence (AI)-Enhanced Ultrasound Techniques Used in Non-Alcoholic Fatty Liver Disease: Are They Ready for Prime Time?
by Elena Codruta Gheorghe, Carmen Nicolau, Adina Kamal, Anca Udristoiu, Lucian Gruionu and Adrian Saftoiu
Appl. Sci. 2023, 13(8), 5080; https://doi.org/10.3390/app13085080 - 19 Apr 2023
Cited by 3 | Viewed by 2741
Abstract
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic liver disease, affecting approximately 2 billion individuals worldwide with a spectrum that can range from simple steatosis to cirrhosis. Typically, the diagnosis of NAFLD is based on imaging studies, but the [...] Read more.
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent cause of chronic liver disease, affecting approximately 2 billion individuals worldwide with a spectrum that can range from simple steatosis to cirrhosis. Typically, the diagnosis of NAFLD is based on imaging studies, but the gold standard remains liver biopsies. Hence, the use of artificial intelligence (AI) in this field, which has recently undergone rapid development in various aspects of medicine, has the potential to accurately diagnose NAFLD and steatohepatitis (NASH). This paper provides an overview of the latest research that employs AI for the diagnosis and staging of NAFLD, as well as applications for future developments in this field. Full article
(This article belongs to the Special Issue New Ultrasound Techniques—Applications in Internal Medicine)
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