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Magnetic Nanoparticles in Theranostic and Health Applications

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Materials Science and Engineering".

Deadline for manuscript submissions: closed (30 January 2026) | Viewed by 1559

Editors


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Guest Editor
Institute of Joint Research in Nanoscience and Materials of Aragon (INMA), Department of Condensed Matter Physics, Faculty of Sciences, The University of Zaragoza, 50018 Zaragoza, Spain
Interests: sonochemistry; process intensification; biomedical engineering; nanotherapy; magnetic materials; drug-loading; surface modification; inductive heating; smart drug-delivery systems; remote-triggered release kinetics

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Guest Editor
Escuela Superior de Apan, Universidad Autónoma del Estado de Hidalgo, Carretera Apan-Calpulalpan, Km 8, Chimalpa Tlalayote, Apan 43900, Mexico
Interests: gold and silver nanoparticles; synthesis and applications; sonochemistry; electrospinning; nanofluids; study of thermal diffusivity; density functional theory

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Guest Editor
Physics Department, Center for Research and Advanced Studies of the National Polytechnic Institute, CINVESTAV-IPN, Ciudad de México 07360, Mexico
Interests: solid state physics; synthesis of nanoparticles; theranostics; electron microscopy; scanning probe microscopy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Magnetic micro and nanoparticles have garnered significant interest in the pharmaceutical area. Inorganic and hybrid magnetic materials offer numerous advantages for theranostic applications, including the non-invasive, controlled, tuned, and targeted release of therapeutic agents using external stimuli and sensing capabilities for the early detection and monitoring of diseases.

This Special Issue aims to present scientific publications exploring material processing routes for the development of new systems with theranostic capabilities and their process intensification. Besides colloidal systems, we welcome reports on sensing, targeting, therapeutic, and drug delivery strategies implemented for the development of hybrid and composite smart materials. The focus encompasses strategies for non-invasive and biocompatible treatments and sensing using multifunctional magnetic materials as promising alternatives for improving current treatments across a spectrum of diseases, including metabolic, neural, and tumoral affections.

We invite the submission of high-quality contributions for this Special Issue. Reviews and original research articles are welcome. Potential topics include, but are not limited to, the following:

  1. Innovative manufacturing routes;
  2. Multifunctional hybrid material processing;
  3. New properties and capabilities for theranostics;
  4. Device implementation;
  5. Challenges in synthesis and industrial scale-up;
  6. Reactive Oxygen Species detection and generation;
  7. New approaches in targeted drug delivery;
  8. Smart drug release;
  9. Localized heating and hyperthermia;
  10. Magnetically triggered responses.

Dr. Jesús A. Fuentes-García
Prof. Dr. J. A. Pescador-Rojas
Prof. Dr. Jaime Santoyo-Salazar
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • process intensification, tailored surficial modification, and synergistic effects
  • biomedicine
  • magnetic materials
  • magnetic composites
  • multifunctional micro and nano systems
  • drug delivery systems
  • process intensification

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Published Papers (1 paper)

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Research

17 pages, 3693 KB  
Article
A Stimuli-Responsive Hybrid Platform for the On-Demand Delivery of Vitamin B12
by Sara Huerta-Cebollada and Jesús Antonio Fuentes-García
Appl. Sci. 2026, 16(4), 1997; https://doi.org/10.3390/app16041997 - 17 Feb 2026
Viewed by 560
Abstract
Physically triggered drug release is an emerging field focused on developing materials capable of modulating release kinetics in response to external stimuli. In this work, we present a strategy for the fabrication and evaluation of heat-mediated drug release from electrospun fibers composed of [...] Read more.
Physically triggered drug release is an emerging field focused on developing materials capable of modulating release kinetics in response to external stimuli. In this work, we present a strategy for the fabrication and evaluation of heat-mediated drug release from electrospun fibers composed of a polyacrylonitrile (PAN) and poly (methyl vinyl ether-alt-maleic acid) (PMA-MVE) blend, encapsulating vitamin B12 (B12-NFs) as a model. Following thermal treatments at 90, 120, and 180 °C, results from SEM, TGA, DSC, and FTIR confirmed that increasing the crosslinking temperature promoted the formation of a more hydrophobic matrix (contact angle > 150°), which effectively reduced spontaneous drug leakage. As a proof-of-concept, we evaluated the sensitivity of the elaborated B12 to heating in aqueous media using UV-Vis spectrometry. The results indicate that the release kinetics followed a sigmoidal profile governed by the dissolution Gompertz model. This laboratory-scale evaluation establishes the fundamental mechanisms for magnetically triggered platforms based on polymeric blends, providing a robust framework for the design of remotely activated, non-invasive drug delivery platforms. Full article
(This article belongs to the Special Issue Magnetic Nanoparticles in Theranostic and Health Applications)
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