Probiotics, Prebiotics, Postbiotics: From Mechanisms to Applications
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Food Science and Technology".
Deadline for manuscript submissions: 10 December 2025 | Viewed by 8

Special Issue Editor
Interests: probiotics; postbiotics; nanomaterial bioapplication; foodborne pathogens
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
This Special Issue will explore the mechanisms and diverse applications of probiotics, prebiotics, and postbiotics in promoting health and addressing complex pathologies, with a focus on technological innovations in their formulation and optimization. Probiotics, prebiotics, and postbiotics play a critical role in modulating microbiota composition and systemic physiological homeostasis. Core research themes include their efficacy in alleviating liver injury, enhancing metabolic detoxification processes, and mitigating oxidative stress and inflammatory responses.
The scope of this Special Issue covers innovative applications in functional foods and formulation technologies to improve strain stability and bioavailability during production, storage, and gastrointestinal transit. Additionally, this Special Issue will emphasize the optimization of probiotic encapsulation techniques for intestine-targeted delivery, their controlled-release efficacy, and their potential in personalized nutritional interventions. Submissions may focus on mechanistic studies (e.g., gut microbiota modulation, short-chain fatty acid synthesis), animal models, clinical trials, or translational research, while addressing challenges such as strain specificity, scalable manufacturing processes, and regulatory safety evaluations.
We welcome multidisciplinary contributions across fields including microbiology, food engineering, pharmaceutical research and development, and nutritional sciences to advance the frontiers of applications of probiotics/prebiotics/postbiotics in therapeutic strategies, functional food development, and precision health management.
Prof. Dr. Hengyi Xu
Guest Editor
Manuscript Submission Information
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Keywords
- probiotics
- prebiotics
- postbiotics
- gut microbiota modulation
- health intervention
- functional foods
- metabolic detoxification
- probiotic encapsulation
- formulation stability
- oxidative stress
- personalized nutrition
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