Submit to Special Issue Submit Abstract to Special Issue Review for Applied Sciences Propose a Special Issue

Journal Menu

Journal Browser

Application of Magnetic Nanoparticles

Print Special Issue Flyer
Special Issue Editors
Special Issue Information
Keywords
Benefits of Publishing in a Special Issue
Published Papers

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Nanotechnology and Applied Nanosciences".

Deadline for manuscript submissions: 30 July 2026 | Viewed by 2398

Share This Special Issue

Special Issue Editors

Prof. Dr. Alex Campos

E-Mail Website
Guest Editor

Faculty UnB Planaltina, International Physics Center, University of Brasília, Brasília 73345-010, DF, Brazil
Interests: magnetic nanocomposites and nanocolloids for technological applications
Special Issues, Collections and Topics in MDPI journals

Dr. Guilherme Gomide

E-Mail Website
Guest Editor

Instituto de Física, Universidade de Brasília, Brasília 70904-970, DF, Brazil
Interests: condensed matter physics at the nanoscale; nanomagnetism; magnetic and multifunctional colloids; magnetic nanoparticles' structure and magnetism
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Magnetic nanoparticles (MNPs) have emerged as a highly versatile class of nanomaterials with applications spanning biomedicine, environmental remediation, catalysis, and energy-related technologies. Their unique magnetic behavior, size-dependent properties, and surface tunability enable advanced functionalities in drug delivery systems, magnetic resonance imaging (MRI), hyperthermia treatment, targeted separation, and nanoscale sensing. Ongoing research has increasingly focused on the rational design of MNPs and magnetic nano(bio)hybrids, emphasizing structure–property relationships and multifunctionality. This Special Issue aims to bring together recent advances in the synthesis, functionalization, characterization, and applications of magnetic nanoparticles, highlighting innovative strategies that bridge fundamental studies with real-world applications. By showcasing interdisciplinary contributions, this collection underscores the fundamental role of magnetic nanomaterials in addressing global challenges through technological innovation and sustainable solutions.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

Synthesis and design of magnetic nanoparticles;
Structural, dynamic, and functional characterization of magnetic nanoparticles;
Multifunctional magnetic nanoparticles, including (bio)organic nanoassemblies and nano(bio)hybrids;
Structure–property relationships in magnetic nanoparticles and nano(bio)hybrids;
Theory, statistical mechanics, and computer simulations;
Nanomagnetism and advances in life science applications;
Magnetic nanomaterials for environmental and energy-related applications.

We look forward to receiving your contributions.

Prof. Dr. Alex Campos
Prof. Dr. Guilherme Gomide
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

nanomagnetism
magnetic nanoparticles
magnetic nano(bio)hybrids

Benefits of Publishing in a Special Issue

Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (5 papers)

Download All Papers

Order results

Result details

Show export options Show export options

Select all

Export citation of selected articles as:

Research

18 pages, 4451 KB

Open AccessArticle

Synthesis and Characterization of Size- and Shape-Controlled CoFe₂O₄ Nanoparticles via Polyvinylpyrrolidone (PVP)-Assisted Hydrothermal Synthesis

by Rareș Bortnic, Tamás Szilárd, Ádám Szatmári, Razvan Hirian, Rareș Ionuț Știufiuc, Alin-Iulian Moldovan, Roxana Dudric and Romulus Tetean

Appl. Sci. 2026, 16(7), 3547; https://doi.org/10.3390/app16073547 - 4 Apr 2026

Viewed by 327

Abstract

CoFe₂O₄ nanoparticles were prepared using a hydrothermal method. All the studied samples were single-phase and were crystallized in a cubic Fd-3m structure. XRD and TEM analyses revealed that the particles had average sizes between 5 and 22 nm. It has been shown that, by using the PVP of different molecular masses, trends of growth and crystallization can be established, obtaining elongated 40 k, cubical 58 k, and rhomboidal 360 kg/mol nanoparticles. While using Ethylene glycol as solvent, the formation of separated “raspberry”-like nanostructures was revealed. The saturation magnetizations are somewhat smaller compared with crystalline CoFe₂O₄ saturation magnetization, but are high enough to have possible biomedical applications. FC and ZFC measurements show that the blocking temperature was around 100 K for the CF5 sample and around 20 K for the FC6 sample. The calculated anisotropy constants were between 7 and 10 kJ/m³, being close to previously reported values. The calculated blocking temperatures are in good agreement with experimental ones. The M_r/Ms ratio at room temperature was lower than 0.5, confirming the predominance of magnetostatic interactions. This paper serves as a good starting point for researchers seeking to synthesize a CoFe₂O₄ system with a desired size and growth tendency at the nanometer scale. Full article

(This article belongs to the Special Issue Application of Magnetic Nanoparticles)

► Show Figures

Figure 1

15 pages, 2361 KB

Open AccessArticle

Frequency and Polarizing Magnetic Field Dependence of the Clausius–Mossotti Factor of a Kerosene-Based Ferrofluid with Mn-Fe Nanoparticles in a Microwave Field

by Iosif Malaescu, Paul C. Fannin, Catalin Nicolae Marin, Ioana Marin and Corneluta Fira-Mladinescu

Appl. Sci. 2026, 16(6), 2945; https://doi.org/10.3390/app16062945 - 18 Mar 2026

Viewed by 227

Abstract

We present frequency- and magnetic field-dependent measurements of the complex dielectric permittivity ε*(f, H) of a kerosene-based ferrofluid, containing Mn₀.₆Fe₀.₄Fe₂O₄ nanoparticles, over 0.8–5 GHz and static fields up to ~91 kA/m. The [...] Read more.

ε_{F}^{″}

, shows a peak at a characteristic frequency that shifts towards higher frequencies with increasing H, revealing a magnetic field-dependent relaxation process, interpreted using the Maxwell–Wagner–Sillars model. The dielectrophoretic extraction of nanoparticles was evaluated via the squared electric field gradient, and a threshold,

{(\nabla E^{2})}_{\min}

, dependent on particle size was determined. Below that threshold, Brownian forces dominate, so the ferrofluid acts as a homogeneous dielectric. For this case, the Clausius–Mossotti factor (CM) was calculated for ferrofluid droplets in air and in water as a function of frequency and magnetic field. In air, CM exhibits modest but systematic magnetic field dependence, indicating a magnetically modulated dielectric response at GHz frequencies. In contrast, when water is used as the reference medium, CM remains negative and essentially independent of H across the entire frequency range, suggesting that the high permittivity of water masks the magneto-dielectric effects in the ferrofluid. These findings provide insight into the interplay between the magnetic field and the permittivity of ferrofluids, with implications for high-frequency applications. Moreover, using a λ/4 antenna connected to a network analyzer, the existence of the dielectrophoretic force acting on a ferrofluid-impregnated textile thread at microwave frequencies was experimentally demonstrated. Full article

(This article belongs to the Special Issue Application of Magnetic Nanoparticles)

► Show Figures

Figure 1

15 pages, 4002 KB

Open AccessArticle

Radiofrequency-Induced Disassembly of Insulin Fibrillar Structures Using Functionalized Magnetic Nanoparticles

by Natália Andrýsková, Veronika Benková, Melánia Babincová, Peter Babinec and Štefan Durdík

Appl. Sci. 2026, 16(5), 2473; https://doi.org/10.3390/app16052473 - 4 Mar 2026

Viewed by 286

Abstract

Amyloidosis is characterized by the deposition of misfolded proteins as highly stable, insoluble β-sheet-rich fibrils, posing a major therapeutic challenge due to their resistance to degradation. Insulin-derived amyloidosis at subcutaneous injection sites is a clinically significant complication in patients with diabetes, leading to impaired insulin absorption, unpredictable glycemic control, substantially increased insulin dose requirements, and localized masses (amyloidomas) that may require surgical excision when symptomatic. In this study, we evaluated sodium oleate-functionalized magnetic nanoparticles (MNs) with a hydrodynamic diameter of 50 nm with a magnetite (iron oxide—Fe₃O₄) core as a targeted physical intervention to disrupt preformed insulin amyloid fibrils. The strategy exploits localized nanoscale hyperthermia generated by MNs under a high-frequency radiofrequency (RF) field (1.65 MHz). Fibril integrity and disassembly kinetics were assessed using Thioflavin T (ThT) fluorescence assays and fluorescence microscopy. RF-activated MNs induced rapid, concentration-dependent fibril disruption; notably, at 2 mg/mL MNs, near-complete disassembly was achieved within 15 min—a timeframe compatible with clinical procedures. Neither RF nor MNs alone produced significant effects, confirming a synergistic magnetothermal mechanism. These results provide a proof of concept for a minimally invasive, externally triggered approach to clear localized insulin amyloid deposits, offering promising potential as a novel therapeutic strategy for managing injection-site amyloidosis in diabetic patients, where current options remain limited and often inadequate. Full article

(This article belongs to the Special Issue Application of Magnetic Nanoparticles)

► Show Figures

Figure 1

24 pages, 3143 KB

Open AccessArticle

Modulating Peroxidase-like Activity of Fe₃O₄@Pt@poly-LDOPA and Its Application as Multifunctional Magnetic Probes Towards SARS-CoV-2 Detection

by Lorico Delos Santos Lapitan, Jr., Jan Olgierd Górniaszek, Maciej Trzaskowski and Mariusz Pietrzak

Appl. Sci. 2026, 16(4), 1858; https://doi.org/10.3390/app16041858 - 12 Feb 2026

Viewed by 647

Abstract

We report a Fe₃O₄@Pt@poly-LDOPA nanozyme that displays enhanced peroxidase (POD)-like activity. Polymerisation of levodopa onto the surface of Fe₃O₄@Pt yields a carboxyl-rich poly-LDOPA shell that is available for bioconjugation with antibodies and other types of receptors. Physicochemical characterisation confirmed the integrity of the Fe₃O₄ core, successful Pt modification, and formation of the polymer coating under acidic and basic conditions. Steady-state kinetic analysis using the Michaelis–Menten model revealed robust catalytic performance toward both substrates: for H₂O₂, V_max = 4.0 × 10⁻⁸ M·s⁻¹ and K_m = 25.13 mM; for TMB, V_max = 6.07 × 10⁻⁸ M·s⁻¹ and K_m = 0.229 mM, indicative of high turnover and strong apparent affinity for the chromogenic substrate. A nanozyme-linked immunosorbent assay for the SARS-CoV-2 nucleocapsid was developed. The anti-nucleocapsid antibodies were immobilised onto Fe₃O₄@Pt@poly-LDOPA via EDC/NHS. In buffer, the calibration range (1.0–100 ng·mL⁻¹) afforded an LOD of 6.95 ng·mL⁻¹. In 10% human serum, reduced background and improved nanozyme dispersion yielded a linear low-concentration response (0.1–10 ng·mL⁻¹), with an LOD of 0.0036 ng·mL⁻¹. These results establish Fe₃O₄@Pt@poly-LDOPA as a promising inorganic–organic nanozyme platform that combines catalytic effectiveness, magnetic manipulability, and facile bioconjugation for immunosensing of various disease-related biomarkers. Full article

(This article belongs to the Special Issue Application of Magnetic Nanoparticles)

► Show Figures

Figure 1

12 pages, 2195 KB

Open AccessArticle

Field-Controlled Magnetisation Patterns in Three-Arm Star-Shaped Nanoparticles as Prototypes of Reconfigurable Routing and Vortex State Memory Devices

by Dominika Kuźma, Piotr Zegan, Yaroslav Parkhomenko and Piotr Zieliński

Appl. Sci. 2026, 16(2), 1145; https://doi.org/10.3390/app16021145 - 22 Jan 2026

Viewed by 267

Abstract

A model of nanoparticles has been designed to partially resemble self-similar ferroelastic star-like domain textures. Numerical computations have been used to find the equilibrium configurations of magnetisation in such systems. As expected from the symmetry, the self-similar initial states give room to other types of domain structure as a function of the star parameters. When relaxed without an external field, the self-similar pattern mostly turns into a massive vortex in the centre with radially oriented domains in the star’s peripheral arms. In contrast, a random initial state ends up in a configuration of a triple valve with one input and two outputs, or vice versa, analogous to logical gates. A treatment with an in-plane magnetic field always leads to the valve configuration. The triple-valve states turn out stable, whereas the vortex ones are metastable. The results may be in the design of magnetic-based logic devices. Full article

(This article belongs to the Special Issue Application of Magnetic Nanoparticles)

► Show Figures

Journal Menu

Journal Browser

Application of Magnetic Nanoparticles

Share This Special Issue

Special Issue Editors

Special Issue Information

Keywords

Benefits of Publishing in a Special Issue

Published Papers (5 papers)

Research

Further Information

Guidelines

MDPI Initiatives

Follow MDPI