Current Techniques for Bone Regeneration
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".
Deadline for manuscript submissions: 20 February 2026 | Viewed by 24
Special Issue Editor
Interests: development of delivery techniques; development of new imaging techniques; differentiation of stem cells; role of hormones and growth factors
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Bone regeneration is a dynamic and evolving field addressing the growing need to repair bone defects resulting from trauma, disease, or age-related degeneration. This Special Issue explores state-of-the-art strategies and technologies aimed at enhancing bone repair, with a particular focus on the convergence of biology, materials science, and bioengineering.
Recent innovations include the use of stem cell-based therapies—particularly mesenchymal stem cells (MSCs) and induced pluripotent stem cells (iPSCs)—as well as the development of biomimetic scaffolds, smart delivery systems, and gene-editing techniques. Biomimetic peptides have emerged as a promising class of therapeutics that mimic native signaling molecules to activate specific regenerative pathways. These peptides offer high target specificity, low immunogenicity, and the potential to synergize with scaffolds and growth factors such as BMP-2 or VEGF for enhanced osteoinduction.
In addition, 3D-printed constructs, nanoengineered surfaces, and controlled drug delivery platforms are being used to recapitulate the complex microenvironment of bone tissue. Immunomodulatory therapies, mechanical stimulation, and in silico modeling are also gaining traction for optimizing regeneration outcomes.
We welcome contributions spanning basic science, translational studies, and clinical applications, particularly those addressing integration, vascularization, and regulatory challenges in bone regeneration.
Dr. Anja Nohe
Guest Editor
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Keywords
- bone regeneration
- biomimetic peptides
- tissue engineering
- stem cell therapy
- biomaterials
- growth factor delivery
- 3D-printed scaffolds
- osteoinduction
- immunomodulation
- bone repair strategies
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