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Design, Synthesis, and Applications of Novel Antimicrobial Materials

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Materials Science and Engineering".

Deadline for manuscript submissions: 20 July 2026 | Viewed by 818

Special Issue Editors


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Departamento de Química de Radiaciones y Radioquímica, Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, México 04510, DF, Mexico
Interests: polymers; smart polymers; enzymes; dendrimers; radiation grafting; drug delivery
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Chemistry, CUCEI, University of Guadalajara, Blvd. Marcelino García Barragán 1421, Guadalajara 44430, Jalisco, Mexico
Interests: nanomaterials; hydrogels; emulsion and microemulsion polymerization; bone cements; water contaminant removal

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Guest Editor
Instituto de Investigaciones en Materiales, Universidad Nacional Autónoma de México, Mexico City 04510, Mexico
Interests: polymer synthesis and characterization; polymeric and composite materials; tissue restoration; guided tissue engineering

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Guest Editor
Departamento de Química de Radiaciones y Radioquímica, Instituto de Ciencias Nucleares, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, 04510 México DF, Mexico
Interests: hydrogels, polymers; smart polymers; radiation grafting; drug delivery, nanoparticles, surface functionalization
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Rapid advances in materials science have catalyzed the emergence of a new generation of antimicrobial materials, designed with unprecedented precision to combat microbial proliferation across a wide range of critical applications. This multidisciplinary field combines polymer, ceramic, and metal alloy engineering with the strategic incorporation of active agents at the micro-, nano-, or molecular scale. The primary objective of using these materials is to confer intrinsic antimicrobial properties, whether passive or active, to surfaces and matrices that traditionally lack them.

The innovation lies in these materials' ability to integrate metallic nanoparticles, specific pharmaceutical compounds, or biologically active agents, such as antimicrobial peptides (AMPs) and enzymes. Their architecture also allows for surface loading or functionalization with antimicrobial chemical groups, such as quaternary ammonium salts or iminium salts, which exert direct inhibitory action on bacterial and fungal growth. Nanoscale engineering is fundamental for optimizing the bioavailability of the antimicrobial agent, maximizing the surface area in contact with microorganisms, and ultimately enhancing biocidal efficacy.

Implementing these advanced systems can revolutionize various sectors. In healthcare, they facilitate the development of medical devices with reduced risk of nosocomial infections and implant coatings. In environmental and water treatment applications, they offer solutions for purification and biocorrosion mitigation. Likewise, in the food industry, they extend product shelf life through active packaging, and in textiles, they provide improved durability against microbial degradation. A deep understanding of the mechanisms of action and the optimization of material–microorganism interactions are crucial for the continued evolution and success of this emerging technology.

Dr. Guadalupe G. Flores-Rojas
Dr. Eduardo Mendizábal
Dr. Ricardo Vera Graziano
Dr. Emilio Bucio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial activity
  • polymer
  • metal alloy, nanoparticles
  • coating
  • enzyme immobilization
  • drug delivery

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Published Papers (1 paper)

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Research

15 pages, 2999 KB  
Article
Cu@Ag Nanoparticles Coating onto Polyethylene Terephthalate Films Functionalized with Amino Groups: Antimicrobial Activity
by Osiris Farias-Elvira, Guadalupe Gabriel Flores-Rojas, Lourdes Adriana Pérez-Carrillo, Emilio Bucio, Ricardo Vera-Graziano and Eduardo Mendizábal
Appl. Sci. 2026, 16(3), 1603; https://doi.org/10.3390/app16031603 - 5 Feb 2026
Viewed by 470
Abstract
Poly(ethylene terephthalate) (PET) is widely used in various sectors due to its biocompatibility, mechanical strength, and chemical stability. However, its inert surface makes it challenging to functionalize and coat with antimicrobial agents to prevent microbial growth and biofilm formation. Therefore, in this work, [...] Read more.
Poly(ethylene terephthalate) (PET) is widely used in various sectors due to its biocompatibility, mechanical strength, and chemical stability. However, its inert surface makes it challenging to functionalize and coat with antimicrobial agents to prevent microbial growth and biofilm formation. Therefore, in this work, antimicrobial activity was imparted to PET films using a Cu@Ag nanoparticle coating. The resulting materials were characterized by spectroscopic, thermal, and microscopic techniques, and their mechanical properties and antimicrobial efficacy against S. aureus and E. coli were evaluated. The results demonstrated significant antimicrobial activity and good retention of PET’s mechanical and thermal properties, which are relevant for potential applications in the biomedical and packaging sectors, where infection prevention is crucial. Full article
(This article belongs to the Special Issue Design, Synthesis, and Applications of Novel Antimicrobial Materials)
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