Role of the Transcription Factor NRF2 in Neurodegenerative Disorders
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (30 September 2023) | Viewed by 2532
Special Issue Editor
2. Instituto de Investigaciones Biomédicas “Alberto Sols” UAM-CSIC, Arturo Duperier 4, 28029 Madrid, Spain
3. Institute Teófilo Hernando for Drug Discovery, Universidad Autónoma de Madrid, 28029 Madrid, Spain
4. Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED), Instituto de Salud Carlos III, 28031 Madrid, Spain
Interests: Parkinson’s disease; tauopathies; Amyotrophic lateral sclerosis; NRF2; mitochondria; neuroinflammation; oxidative stress
Special Issue Information
Dear Colleagues,
The aging of the population poses a growing burden in society. This is associated with the increase in disability and diseases that have a high impact on health care, on patients and their families. Likewise, aging is associated with the appearance of neurodegenerative diseases. Although each of these diseases has its own characteristics, they all share altered proteostasis, oxidative stress and neuroinflammation. In recent years, it has been described that the transcription factor NRF2 is involved in the modulation of all these processes, becoming a pleiotropic factor. Therefore, understanding the involvement of NRF2 in the different mechanisms associated with neurodegeneration may be of vital importance in establishing new therapeutic targets.
As guest editor, I invite you to contribute to this Special Issue, whose focus will be the role of NRF2 in neurodegenerative disorders.
We also invite researchers in the field and the participants of The COST Action CA20121, Bench to Bedside Transition for Pharmacological regulation of NRF2 in non-communicable diseases (BenBedPhar) to submit their latest research findings to this Special Issue. We look forward to reading your contributions.
Prof. Dr. Isabel Lastres-Becker
Guest Editor
Manuscript Submission Information
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Keywords
- Alzheimer’s disease
- down syndrome
- parkinson’s disease
- Huntington’s disease
- amyotrophic lateral sclerosis
- ischemia
- oxidative stress
- neuroinflammation
- proteostasis
- mitochondria
