Lipid Metabolic Stress in Neurodegeneration
A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 384
Special Issue Editors
Interests: glial physiology; ionic homeostasis; electrophysiology; gasotransmitters
Special Issues, Collections and Topics in MDPI journals
Interests: neuronal metabolism; neurodegeneration; lipid homeostasis; cellular ageing
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Lipid molecules, which account for 50% of the brains dry weight, are pivotal to maintaining the architecture and function of the brain. There is a growing appreciation of both cellular and regional-specific regulation of lipid metabolism within the central nervous system. For example, advances in cell-specific profiling of lipids and metabolic pathways has indicated a high degree of diversity within subsets of neurochemically distinct neurons. This diversity and the impact of changes in cell-specific lipid profiles in healthy ageing needs to be explored further to further our understanding. However, accumulating evidence indicates that lipid metabolism is a driving factor in promoting neurological conditions, and therefore, mechanistic insights can provide novel therapeutic avenues to explore combating neurodegenerative diseases. This Special Issue invites submissions that demonstrate the complexity of cellular lipid metabolism from both neurons and glia and capturing in vitro and in vivo responses to further our understanding of this developing area of neuroscience research.
Dr. Mark Dallas
Dr. Hugo Fernandes
Guest Editors
Manuscript Submission Information
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Keywords
- lipids
- oxidative stress
- neurodegeneration
- polyunsaturated fatty acids
- arachidonic acid
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