Intra-abdominal Infections: From Diagnosis to Source Control
A special issue of Antibiotics (ISSN 2079-6382).
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 2237
Special Issue Editor
Special Issue Information
Dear Colleagues,
Intra-abdominal infections encompass a wide spectrum of disease states, ranging from uncomplicated appendicitis to fecal peritonitis. In uncomplicated intra-abdominal infections, the infectious process only involves a single organ and does not spread to the peritoneum. In complicated infections, the infectious process extends beyond a singularly affected organ, and causes either localized peritonitis or diffuse peritonitis. The treatment of complicated intra-abdominal infections involves both source control and antibiotic therapy. Source control encompasses all measures undertaken to eliminate the source of infection and to control ongoing contamination. Surgery is the most common and most important therapeutic action in managing intra-abdominal infections. Procedure choice depends on the anatomical source of infection, on the degree of peritoneal inflammation, on the generalized septic response and on the patient’s general condition. Antimicrobial therapy plays an integral role in the management of intra-abdominal infections, especially in critically ill patients requiring immediate empiric antibiotic therapy. Empiric antibiotic therapy accounts for the most frequently isolated microorganisms as well as any local trends of antibiotic resistance. All aspects of management are equally important and the action panorama is progressively changing into a more specific and targeted action. The concept of source control is evolving together with the technical, scientific and management innovations.
The present Special Issue will focus on all aspects of intra-abdominal infection diagnosis and management, both in surgery and in the ICU.
Prof. Dr. Federico Coccolini
Guest Editor
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