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Journals
Antibiotics
Special Issues
Silver Nanoparticles as Antimicrobials Materials
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Silver Nanoparticles as Antimicrobials Materials

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Novel Antimicrobial Agents".

Deadline for manuscript submissions: closed (31 October 2019) | Viewed by 4039

Special Issue Editor

Dr. Shima Taheri

E-Mail Website1 Website2
Guest Editor
Faculty of Science and Engineering, Macquarie University, Sydney, Australia
Interests: smart self-healing concrete; concrete structural health monitoring; cementitious materials; nanotechnology; advanced manufacturing; materials science and engineering; adhesives, sealants, and coatings
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The development of silver nanoparticle (AgNPs) as a potent alternative to conventional antibiotics has been extensively investigated over recent decades. Silver containing nanostructures, as antimicrobial materials, are of potential interest for various medical, consumer, agricultural and industrial applications from disinfectants to smart drug carriers, biomedical coatings, food packaging, and water purification systems. Variations in factors such as size, shape, aggregation state, and surface chemistry can influence toxicity, stability, biocompatibility, and most importantly antimicrobial capability of AgNPs. These features eventually encouraged extensive further research efforts on elaborating the synthetic routes to allow greater control of nanoparticle physiochemical properties. While potential benefits of antimicrobial AgNPs are attracting increased attention, their broad use however, raises concerns regarding AgNPs fate and their potential adverse effects on environment and human health.

This special issue of “Silver Nanoparticles as Antimicrobials Materials” welcomes various submission types, such as original research articles, case studies, and comparative studies on subjects pertaining to silver nanoparticles and their application as antimicrobials materials. Potential topics include, but are not limited to:

  • Synthesis, Characterization, In Vivo and In Vitro Evaluations of Antimicrobial Silver Nanoparticles 
  • Mechanisms of Action of Antimicrobial Silver Nanoparticles 
  • Durability of Antimicrobial Silver Nanoparticles
  • Biocompatibility Studies
  • Cytotoxicity, Genotoxicity and Inflammatory Effects of Silver Nanoparticles
  • Silver Containing Antimicrobial Nanocoatings and Nanocomposites
  • Industrial Applications of Antimicrobial Silver Nanoparticles such as Food Packaging
  • Future Perspectives for Antimicrobial Silver Nanomaterials 

Dr. Shima Taheri
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • Silver Nanoparticles
  • Medical Silver
  • Antimicrobial
  • Antibacterial
  • Biocompatibility
  • Cytotoxicity
  • Antibiotic Resistance
  • Medical Device Coatings
  • Nanomedicines
  • Inflammatory Response

Published Papers (1 paper)

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Research

19 pages, 4773 KiB  
Article
Antibacterial Effects of Quinazolin-4(3H)-One Functionalized-Conjugated Silver Nanoparticles
by Abdulkader Masri, Ayaz Anwar, Naveed Ahmed Khan, Muhammad Saquib Shahbaz, Khalid Mohammed Khan, Syed Shahabuddin and Ruqaiyyah Siddiqui
Antibiotics 2019, 8(4), 179; https://doi.org/10.3390/antibiotics8040179 - 09 Oct 2019
Cited by 14 | Viewed by 3673
Abstract
Infections due to multi-drug resistant bacteria are on the rise and there is an urgent need to develop new antibacterials. In this regard, a series of six functionally diverse new quinazolinone compounds were synthesized by a facile one-pot reaction of benzoic acid derivatives, [...] Read more.
Infections due to multi-drug resistant bacteria are on the rise and there is an urgent need to develop new antibacterials. In this regard, a series of six functionally diverse new quinazolinone compounds were synthesized by a facile one-pot reaction of benzoic acid derivatives, trimethoxymethane and aniline derivatives. Three compounds of 3-aryl-8-methylquinazolin-4(3H)-one, and 3-aryl-6,7-dimethoxyquinazolin4(3H)-one were prepared and tested against multi-drug resistant bacteria. Furthermore, we determined whether conjugation with silver nanoparticles improved the antibacterial efficacy of these quinazolinone derivatives. The newly synthesized compounds were characterized by ultraviolet visible spectrophotometry (UV-vis), Zetasizer analysis, Fourier transform infrared spectroscopic methods (FT-IR), and scanning electron microscopy (SEM). Using bactericidal evaluation, effects were determined against selected Gram-negative and Gram-positive bacteria. Furthermore, cytotoxicity of nanoconjugates on human cells were determined. The UV-vis spectrum of silver nanoparticles conjugated quinazolinone displayed surface plasmon resonance band in the range of 400–470 nm, and the size of nanoparticles was detected to be in the range of 100–250 nm by dynamic light scattering (DLS). FT-IR study confirmed the stabilization of silver nanoparticles by the presence of diverse functional arayl on each compound. SEM further revealed the construction of spherical nanoparticles. Among the quinazolinone derivative tested, two compounds (QNZ 4, QNZ 6) conjugated with silver nanoparticles showed enhanced antibacterial activity against Escherichia coli K1, Streptococcus pyogenes, Klebsiella pneumoniae, B. cereus and P. aeruginosa as compared to the compounds. Full article
(This article belongs to the Special Issue Silver Nanoparticles as Antimicrobials Materials)
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