From Epidemiology to Intervention: Addressing the Spread of Multidrug-Resistant Microorganisms

Dear Colleagues,

The global rise of multidrug‑resistant (MDR) microorganisms represents one of the most important challenges regarding public health. Understanding their epidemiology is essential for finding effective ways to counteract infection associated with MDR strains. MDR pathogens spread through complex networks involving hospitals, communities, animals, and the environment, driven by factors such as inappropriate antibiotic use, inadequate infection control practices, and global mobility. Epidemiological surveillance—combining molecular typing, real‑time data analysis, and risk factor assessment—enables researchers to track transmission routes and identify emerging hotspots. A new multifaceted approach from a One Health perspective is therefore necessary. Key strategies include strengthening antimicrobial stewardship programs, improving hygiene and sanitation, implementing rapid diagnostic tools, and promoting evidence‑based infection prevention measures. Bridging epidemiology and new therapeutical solutions could reduce the spread of MDR microorganisms and help to safeguard global health.

Dr. Silvia Di Lodovico
Guest Editor

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