Special Issue "Ovine Genetics: Utilizing OMIC Tools to Design Ovine Breeds for the Future"

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Small Ruminants".

Deadline for manuscript submissions: 31 December 2021.

Special Issue Editor

Dr. Malena Serrano Noreña
E-Mail Website
Guest Editor
Departamento de Mejora Genética Animal; INIA Ctra de la Coruña
Interests: animal genetics; molecular genetics; genomic selection; adaptive traits; reproductive metagenomics.

Special Issue Information

Dear Colleagues,

Over the last decade, the overall amount of sheep production has grown worldwide. To improve the sustainability and competitiveness of sheep livestock systems through breeding, new phenotypes linked to sustainable animal productivity can be developed and integrated into breeding schemes to allow for the selection of animals that are resilient and adaptable to current and future environmental challenges. In the last few decades, novel measures targeting economically important traits through phenotypes linked to physiological processes of animals such as body reserve utilization, feed efficiency, metabolic diseases, thermo-tolerance, methane emissions, disease resistance, and reproductive efficiency have been developed. These new phenotypes are costly and difficult to collect and generally have low heritability. Current genomic tools may help to provide information about genetic loci involved in the phenotypic variation of these complex traits and may be integrated into traditional breeding programs in order to improve their ability to cope with new selection objectives.

Dr. Malena Serrano Noreña
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • sheep breeds
  • new phenotypes
  • adaptive traits
  • resilience
  • omic tools
  • genomic selection.

Published Papers (1 paper)

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Research

Article
Genome-Wide Association Studies of Somatic Cell Count in the Assaf Breed
Animals 2021, 11(6), 1531; https://doi.org/10.3390/ani11061531 - 24 May 2021
Viewed by 943
Abstract
A genome-wide association study (GWAS) was performed to identify new single nucleotide polymorphisms (SNPs) and genes associated with mastitis resistance in Assaf sheep by using the Illumina Ovine Infinium® HD SNP BeadChip (680K). In total, 6173 records from 1894 multiparous Assaf ewes [...] Read more.
A genome-wide association study (GWAS) was performed to identify new single nucleotide polymorphisms (SNPs) and genes associated with mastitis resistance in Assaf sheep by using the Illumina Ovine Infinium® HD SNP BeadChip (680K). In total, 6173 records from 1894 multiparous Assaf ewes with at least three test day records and aged between 2 and 7 years old were used to estimate a corrected phenotype for somatic cell score (SCS). Then, 192 ewes were selected from the top (n = 96) and bottom (n = 96) tails of the corrected SCS phenotype distribution to be used in a GWAS. Although no significant SNPs were found at the genome level, four SNPs (rs419096188, rs415580501, rs410336647, and rs424642424) were significant at the chromosome level (FDR 10%) in two different regions of OAR19. The SNP rs419096188 was located in intron 1 of the NUP210 and close to the HDAC11 genes (61 kb apart), while the other three SNPs were totally linked and located 171 kb apart from the ARPP21 gene. These three genes were related to the immune system response. These results were validated in two SNPs (rs419096188 and rs424642424) in the total population (n = 1894) by Kompetitive Allele-Specific PCR (KASP) genotyping. Furthermore, rs419096188 was also associated with lactose content. Full article
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Genome-wide association studies of somatic cell count in the Assaf breed
Authors: Öner , Y.; Serrano M.; Sarto M. P.; Iguacel L. P.; Piquer-Sabanza M.; Estrada O.; Juan T.; Calvo J. H.
Affiliation: Departamento de Mejora Genética Animal; INIA Ctra de la Coruña, Spain

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