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Animals
Special Issues
Novel Diagnostic and Treatment Approaches to Cardiovascular Diseases in Animals
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Novel Diagnostic and Treatment Approaches to Cardiovascular Diseases in Animals

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Veterinary Clinical Studies".

Deadline for manuscript submissions: closed (20 October 2023) | Viewed by 8095

Special Issue Editors

Prof. Dr. Ryou Tanaka

E-Mail Website
Guest Editor
Department of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo 183-0054, Japan
Interests: cardiothoracic surgery; veterinary cardiology; echocardiography; veterinary medicine
Special Issues, Collections and Topics in MDPI journals
Dr. Ahmed S. Mandour

E-Mail Website
Guest Editor
1. Department of Veterinary Medicine, Tokyo University of Agriculture and Technology, Tokyo, Japan
2. Department of Animal Medicine, Suez Canal University, Ismailia, Egypt
Interests: veterinary internal medicine; veterinary cardiology; echocardiography; diagnostic imaging; biomarkers

Special Issue Information

Dear Colleagues,

There is an increasing understanding of cardiovascular disorders in animals because of the utilization of diagnostic facilities by practitioners. Many research studies in cardiovascular research in human and animal models are now looking for new techniques rather than conventional methods of diagnosis for rapid assessment of the heart to enable early detection of heart failure, enhance outcomes, or build up new effective therapeutic strategies. This Special Issue is aimed at gathering recent studies utilizing new diagnosis and treatment techniques concerning cardiovascular medicine in veterinary practice.

Prof. Dr. Ryo Tanaka
Dr. Ahmed S. Mandour
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • animals
  • heart failure
  • diagnosis
  • treatment

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Published Papers (2 papers)

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Research

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12 pages, 764 KiB  
Article
Beraprost Sodium for Pulmonary Hypertension in Dogs: Effect on Hemodynamics and Cardiac Function
by Ryohei Suzuki, Yunosuke Yuchi, Takahiro Saito, Yuyo Yasumura, Takahiro Teshima, Hirotaka Matsumoto and Hidekazu Koyama
Animals 2022, 12(16), 2078; https://doi.org/10.3390/ani12162078 - 15 Aug 2022
Cited by 6 | Viewed by 3226
Abstract
Pulmonary hypertension (PH) is a fatal condition that affects many dogs. In humans, PH is often treated with beraprost sodium (BPS). However, the effectiveness of BPS for canine PH has not been established. This study aimed to evaluate the clinical and cardiovascular response [...] Read more.
Pulmonary hypertension (PH) is a fatal condition that affects many dogs. In humans, PH is often treated with beraprost sodium (BPS). However, the effectiveness of BPS for canine PH has not been established. This study aimed to evaluate the clinical and cardiovascular response of BPS in canine patients with PH of various causes. Sixteen dogs with PH (post-capillary PH, n = 8; pre-capillary PH, n = 8) were included. BPS was continuously administered twice daily at 15 µg/kg. All dogs underwent echocardiography, including speckle-tracking analysis and blood pressure measurement, before and after BPS administration. Continuous BPS administration (range: 13.2–22.0 µg/kg) significantly decreased the pulmonary and systemic vascular impedance and increased left and right ventricular myocardial strain. In dogs with post-capillary PH, BPS administration caused no significant worsening of the left atrial pressure indicators. No side effects of BPS were observed in any dog. BPS also improved cardiac function and pulmonary circulation through pulmonary vasodilation, suggesting that BPS may be an additional treatment option for canine PH of various causes. Particularly, BPS increased left ventricular function and systemic circulation without worsening the left heart loading condition in dogs with post-capillary PH. Full article
(This article belongs to the Special Issue Novel Diagnostic and Treatment Approaches to Cardiovascular Diseases in Animals)
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Review

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17 pages, 3194 KiB  
Review
Non-Invasive Assessment of the Intraventricular Pressure Using Novel Color M-Mode Echocardiography in Animal Studies: Current Status and Future Perspectives in Veterinary Medicine
by Ahmed S. Mandour, Ahmed Farag, Mahmoud A. Y. Helal, Gamal El-Masry, Salim Al-Rejaie, Ken Takahashi, Tomohiko Yoshida, Lina Hamabe and Ryou Tanaka
Animals 2023, 13(15), 2452; https://doi.org/10.3390/ani13152452 - 29 Jul 2023
Cited by 4 | Viewed by 3375
Abstract
The assessment of diastolic function has received great interest in order to comprehend its crucial role in the pathophysiology of heart failure and for the early identification of cardiac events. Silent changes in the intraventricular flow (IVF) dynamics occur before the deterioration of [...] Read more.
The assessment of diastolic function has received great interest in order to comprehend its crucial role in the pathophysiology of heart failure and for the early identification of cardiac events. Silent changes in the intraventricular flow (IVF) dynamics occur before the deterioration of the cardiac wall, although they cannot be detected using conventional echocardiography. Collective information on left ventricular (LV) pressures throughout the cardiac cycle has great value when dealing with patients with altered hemodynamics. Accurate pressure measurement inside the ventricle can be obtained by invasive methods to determine the LV diastolic pressures, which reflect the myocardial relaxation and compliance. However, catheterization is only feasible in the laboratory setting and is not suitable for clinical use due to its disadvantages. In contrast, echocardiography is simple, safe, and accessible. Color M-mode echocardiography (CMME) is an advanced cardiac evaluation technique that can measure the intraventricular pressure differences (IVPDs) and intraventricular pressure gradients (IVPGs) based on the Doppler shift of the IVF. Recently, the assessment of IVPD and IVPG has gained growing interest in the cardiovascular literature in both animal and human studies as a non-invasive method for the early diagnosis of cardiac dysfunctions, especially diastolic ones. The usability of IVPD and IVPG has been reported in various surgically induced heart failure or pharmacologically altered cardiac functions in rats, dogs, cats, and goats. This report aims to give an overview of the current studies of CMME-derived IVPD and IVPG in animal studies and its feasibility for clinical application in veterinary practice and to provide the prospects of the technique’s ability to improve our understanding. Full article
(This article belongs to the Special Issue Novel Diagnostic and Treatment Approaches to Cardiovascular Diseases in Animals)
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