Physiological Functions of Trace Essential Elements in Animal Organisms

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Physiology".

Deadline for manuscript submissions: closed (31 December 2020) | Viewed by 13188

Special Issue Editor


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Guest Editor
The Kielanowski Institute of Animal Physiology and Nutrition of the Polish Academy of Sciences, Jablonna, Poland
Interests: animal nutrition; ruminant physiology; functional foods; selenium physiology; essential elements; conjugated fatty acid analyses; gas and liquid chromatography; mass spectrometry; nuclear activation analysis; gamma spectrometry

Special Issue Information

Dear Colleagues,

In order to maintain many vital processes trace essential elements, also called as micro-minerals, must be present in living organisms within certain concentration ranges. These bioelements fulfill a lot of important physiological functions like as active centers of enzymes, as structure-forming of biomolecules or as catalysts in the biosynthesis of enzymes and proteins. In animal organisms a lot of trace elements (like selenium, zinc, cobalt or iodine) are the essential part of enzymes; these biomolecules may be involved in the protection of cells against damage by radical oxidative species, transport processes or acute phase reactions. Thus, trace essential elements have diverse functions, including nerve transmission, muscle contraction, blood clotting, immunity, the maintenance of blood pressure and animal growth and development.
Essential elements constitute ~4-6% of animal bodyweight - about one-quarter as phosphorus and one-half as calcium, the remainder being made up of the other essential elements that must be derived from a diet. Therefore, essential elements are divided into two groups according to the amounts present in and needed by the animal organism. The major elements (macro-minerals) - those required in amounts of 100 mg or more per day (i.e., calcium, phosphorus, magnesium, sulfur, sodium, chloride and potassium). The trace elements (micro-minerals), required in much smaller amounts of ~15 mg per day or less, include iron, zinc, copper, manganese, iodine, selenium, fluoride, molybdenum, chromium and cobalt. The term ultratrace elements are used to describe elements that are found in the diet in extremely small quantities (micrograms per day) and are present in animals and human tissue as well; these elements include boron, arsenic, nickel, vanadium and silicon.
Deficiency in any of trace essential elements leads to undesirable pathological conditions that can be prevented or reversed by adequate supplementation of animal diets. On the other hand, dietary excesses of essential elements (like Se, Cr or Cu) can cause direct toxic effects to animals as well as indirect effects that can cause a secondary deficiency of other trace elements. Clinical signs may vary from poor growth and feed utilization to neurologic disorders. Toxic effects vary with the specific essential element in question, the content of that element and its chemical form in a diet, the condition and age of animals, and the absence or presence of certain other dietary components.
Developments in the knowledge of physiological functions of trace essential elements in animal organisms, the influence of dietary essential elements on animal grow parameters, new chemical form of essential elements in diets, interactions between essential elements with other elements or biomolecules in animal organisms, the impact of dietary components, elements on the yield of bioaccumulation of essential trace elements in selected tissues of animals, are needed. Contributions on any of these topics or others related to them, including original research papers and literature reviews, are welcome for this Special Issue.

Prof. Marian Czauderna
Guest Editor

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Keywords

  • trace essential elements
  • farm animals
  • ruminants
  • monogastric animals
  • poultry
  • laboratory animals
  • interactions
  • deficiency symptoms of essential elements
  • excess symptoms of essential elements
  • physiological functions of essential elements
  • toxic elements.

Published Papers (3 papers)

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Research

12 pages, 1922 KiB  
Article
Effects of Iron Deficiency on Serum Metabolome, Hepatic Histology, and Function in Neonatal Piglets
by Zhenglin Dong, Dan Wan, Huansheng Yang, Guanya Li, Yiming Zhang, Xihong Zhou, Xin Wu and Yulong Yin
Animals 2020, 10(8), 1353; https://doi.org/10.3390/ani10081353 - 05 Aug 2020
Cited by 13 | Viewed by 3571
Abstract
Few studies focused on the effects of iron on characterizing alterations of metabolic processes in neonatal piglets. In the present study, 16 neonatal piglets were randomly assigned to two groups. In the first group piglets were given an intramuscularly injection of iron dextran [...] Read more.
Few studies focused on the effects of iron on characterizing alterations of metabolic processes in neonatal piglets. In the present study, 16 neonatal piglets were randomly assigned to two groups. In the first group piglets were given an intramuscularly injection of iron dextran at 150 mg as a positive control (CON) and the second group were not supplemented with iron as a negative control for iron deficiency (ID). At day 8, iron status, serum biochemical parameters, serum metabolome, hepatic histology, and hepatic expression of genes for the metabolism were analyzed. Results indicated that piglets without iron supplementation had significantly reduced iron values and increased blood urea nitrogen concentrations at day 8 (p < 0.05). Analysis of serum metabolome revealed that concentrations of serum lysine, leucine, tyrosine, methionine, and cholesterol were significantly decreased while concentrations of 3-Methyldioxyindole, chenodeoxycholate acid, indoleacetic acid, icosadienoic acid, phenylpyruvic acid, pantothenic acid, ursocholic acid, and cholic acid were significantly increased in iron deficient piglets (p < 0.05). Furthermore, expressions of cyp7a1 and the urea cycle enzyme (ornithinetranscarbamoylase and argininosuccinate synthetase) were significantly increased in iron deficient pigs (p < 0.05). The present experimental results indicated that neonatal piglets without iron supplementation drop to borderline anemia within 8 days after birth. Iron deficiency led to a series of metabolic changes involved in tyrosine metabolism, phenylalanine metabolism, bile secretion, primary bile acid biosynthesis, steroid biosynthesis, and upregulated activities of the urea cycle enzymes in the liver of neonatal piglets, suggesting early effects on metabolic health of neonatal piglets. Full article
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9 pages, 555 KiB  
Article
Effects of Parenteral Supplementation with Minerals and Vitamins on Oxidative Stress and Humoral Immune Response of Weaning Calves
by Guillermo Alberto Mattioli, Diana Esther Rosa, Esteban Turic, Sebastián Julio Picco, Santiago José Raggio, Antonio Humberto Hamad Minervino and Luis Emilio Fazzio
Animals 2020, 10(8), 1298; https://doi.org/10.3390/ani10081298 - 29 Jul 2020
Cited by 15 | Viewed by 3754
Abstract
We aimed to evaluate the effects of injectable mineral and vitamin supplementation on weaning calves subjected to a low-stress (fence-line) weaning system. Seven-month-old Aberdeen Angus female calves (n = 40, 152 ± 11 kg body weight) from a selenium-deficient area of extensive cattle [...] Read more.
We aimed to evaluate the effects of injectable mineral and vitamin supplementation on weaning calves subjected to a low-stress (fence-line) weaning system. Seven-month-old Aberdeen Angus female calves (n = 40, 152 ± 11 kg body weight) from a selenium-deficient area of extensive cattle production on natural grass were randomly assigned to two groups (n = 20 each). One group received subcutaneous supplementation with copper, zinc, selenium, manganese and vitamins A and E (SG), and the other was given sterile saline solution (CG). The animals were supplemented twice, seven days before weaning (day −7) and on the day of weaning (day 0), and they were evaluated 30 (+30) and 60 (+60) days after weaning. Total antioxidant status (TAS), selenium-dependent glutathione peroxidase (GPx) activity, body weight, and average daily gain (ADG) were evaluated. Additionally, antibody titers were assessed prior to and after each immunization with a vaccine containing bovine herpes virus type 1 (BoHV-1). On day +30, body weight (p = 0.03) was higher in SG, whereas TAS (p = 0.02) and GPx (p = 0.0038) activity were lower in CG and remained constant in SG. Antibody titers increased in SG and CG following immunization, being higher in SG on days +30 and +60 (p < 0.05). In conclusion, parenteral supplementation of minerals and vitamins with antioxidant effects in a low-stress weaning system prevented the decrease in TAS and GPx activity, improved antibody response and had positive effects on body weight. Full article
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15 pages, 862 KiB  
Article
Determination of Selenium Species in Muscle, Heart, and Liver Tissues of Lambs Using Mass Spectrometry Methods
by Andrzej Gawor, Anna Ruszczynska, Marian Czauderna and Ewa Bulska
Animals 2020, 10(5), 808; https://doi.org/10.3390/ani10050808 - 07 May 2020
Cited by 14 | Viewed by 3582
Abstract
Identification and quantification of the selenium species in biological tissues is imperative, considering the need to properly understand its metabolism and its importance in various field of sciences, especially nutrition science. Although a number of studies deals with the speciation of selenium, speciation [...] Read more.
Identification and quantification of the selenium species in biological tissues is imperative, considering the need to properly understand its metabolism and its importance in various field of sciences, especially nutrition science. Although a number of studies deals with the speciation of selenium, speciation analysis is still far from being a routine task, and so far strongly depends on the type of the samples. We present a study aimed to examine speciation analysis of Se in tissues of livers, muscles, and hearts obtained from lambs, namely in liver, muscle, and heart. The studied lambs were fed with the diet enriched with an inorganic (as sodium selenate) and organic chemical form of Se (as Se-enriched yeast) compounds with simultaneous addition of fish oil (FO) and carnosic acid (CA). The first part of the work was focused on the optimization of the extraction procedure of selenium compounds from tissues. Next, hyphenated high performance liquid chromatography and inductively coupled plasma mass spectrometry (HPLC–ICP–MS) was used for the identification of five seleno-compounds—Se-methionine (SeMet), Se-cystine (SeCys2), Se-methyl-Se-cysteine (SeMetSeCys), and Se(IV) and Se(VI). Verification of the identified seleno-compounds was achieved using triple-quadrupole mass spectrometer coupled to high performance liquid chromatography (HPLC–ESI–MS/MS). The applied procedure allowed for quantitative analysis of SeMet, SeCys2, and SeMetSeCys, in biological tissues. The developed analytical protocol is feasible for speciation analysis of small molecular seleno-compounds in animals samples. Full article
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