Special Issue "Advances in the Knowledge of Efficacy and Prudent Use of Antimicrobials and Anthelmintics"

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Animal Physiology".

Deadline for manuscript submissions: 30 November 2021.

Special Issue Editors

Dr. Ana M. Sahagun
E-Mail Website
Guest Editor
Department of Biomedical Sciences, Institute of Biomedicine (IBIOMED), Veterinary Faculty, University of Leon, 24071 Leon, Spain
Interests: veterinary pharmacology; pharmacokinetics; antimicrobials and anthelmintic of veterinary use; drug–drug interactions
Dr. Raquel Diez
E-Mail Website
Guest Editor
Department of Biomedical Sciences, Institute of Biomedicine (IBIOMED), Veterinary Faculty, University of Leon, 24071 Leon, Spain
Interests: pharmacology; pharmacokinetics

Special Issue Information

Dear Colleagues,

Antimicrobials and anthelmintics are the most common veterinary medicines used to treat or prevent animal diseases. Indiscriminate and inappropriate use of these drugs can lead to the selection of resistant strains, which may imply a risk to animal or human health, also impacting the environment. This problem becomes even more important in farm animals, in which there is the possibility that small amounts of drugs or their metabolites remain in those animal products that enter the food chain. In the last decade, increasing efforts have been made to promote the prudent use of antimicrobial and anthelmintic drugs in veterinary medicine.

Original research papers on Pharmacokinetics and Pharmacodynamics that contribute to ensuring and improving the knowledge on the efficacy of these drugs in veterinary clinical practice, as well as those related to the design of appropriate dosage regimes, drug consumption, rational use of medicines, or others related to this topic are needed. Review articles are also welcome for this Special Issue.

Dr. Ana M. Sahagun
Dr. Raquel Diez
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial drugs
  • anthelmintic drugs
  • efficacy
  • rational use
  • veterinary medicines

Published Papers (1 paper)

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Research

Article
Effect of Drinking Water Distribution System Design on Antimicrobial Delivery to Pigs
Animals 2021, 11(8), 2362; https://doi.org/10.3390/ani11082362 - 10 Aug 2021
Viewed by 511
Abstract
On many pig farms, growing pigs are mass-medicated for short periods with antimicrobial drugs through their drinking water for metaphylaxis and to treat clinical disease. We conducted a series of four prospective observational cohort studies of routine metaphylactic in-water antibiotic dosing events on [...] Read more.
On many pig farms, growing pigs are mass-medicated for short periods with antimicrobial drugs through their drinking water for metaphylaxis and to treat clinical disease. We conducted a series of four prospective observational cohort studies of routine metaphylactic in-water antibiotic dosing events on a commercial pig farm, to assess the concentration of antimicrobial available to pigs throughout a building over time. Each dosing event was conducted by the farm manager with a differently designed looped water distribution system (WDS). We found that the antimicrobial concentration in water delivered to pigs at drinkers in each pen by a building’s WDS over time was profoundly influenced by the design of the WDS and the pigs’ water usage and drinking pattern, and that differences in the antimicrobial concentration in water over time at drinkers throughout a building could be eliminated through use of a circulator pump in a looped WDS. We also used a hydraulic WDS modelling tool to predict the antimicrobial concentration at drinkers over time during and after a dosing event. Our approach could be used to evaluate alternative in-water dosing regimens for pigs in a specific building in terms of their clinical efficacy and ability to suppress the emergence of antimicrobial resistance, and to determine the optimal regimen. The approach is applicable to all additives administered through drinking water for which the degree of efficacy is dependent on the dose administered. Full article
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Antimicrobial Use in Dairy Calves

Deng Zhaoju

It consists of the antimicrobial usage, factors associated with antimicrobial usage and the antimicrobial resistance in bacterial pathogens associated with dairy calf. 

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