New Perspectives on Canine Mammary Tumour and Therapy

Dear Colleagues,

Canine mammary tumours (CMTs) are still the most often diagnosed tumors in female dogs and are still the cause of death of many animals. There is a significant need for developments in veterinary medicine that will lead to the prolonging of dogs’ lives, and the search for new oncotherapies is particularly crucial. Aside from the fact that patients’ owners have higher expectations about therapy and care for their pets, CMTs are a good model for breast cancer, because of many common clinical and epidemiological similarities, e.g.: the same etiology and course of the disease; similar risk factors and prognostic factors; and the heterogeneity of tumors as well as their spontaneous character. There are also numerous similarities and common features at the molecular level, e.g.: similar transcryptomic profile; overexpression of steroid receptors; epidermal growth factor-proliferation markers; and the presence of cyclooxygenase and metalloproteinases. In recent years, many innovations in veterinary oncology have been proposed, and the aim of this Special Issue is to publish original research papers or reviews concerning an updated overview of pre-clinical and clinical knowledge on the pathophysiology and molecular profiling of CMTs as well as on the development of innovations in the field, either alone or in combination with conventional radio- and chemotherapy.

We invite you to share your recent findings through this Special Issue.

Dr. Joanna Mucha
Guest Editor

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• Canine mammary tumor
• Cancer biology
• Veterinary oncology
• Chemo- and radio-therapy protocols
• Immunotherapy