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Animals
Special Issues
Advances in Canine and Feline Nephrology and Urology
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Advances in Canine and Feline Nephrology and Urology

A special issue of Animals (ISSN 2076-2615). This special issue belongs to the section "Companion Animals".

Deadline for manuscript submissions: 15 February 2026 | Viewed by 1142

Special Issue Editor

Prof. Dr. Joseph Bartges

E-Mail Website
Guest Editor
College of Veterinary Internal Medicine, The University of Georgia, Athens, GA, USA
Interests: urology; urolithiasis; small animals

Special Issue Information

Dear Colleagues,

The field of veterinary nephrology and urology, focusing on the urinary disorders of dogs and cats, is advancing rapidly owing to innovations in diagnosis, treatment, and management strategies. In this Special Issue, entitled “Advances in Canine and Feline Nephrology and Urology”, we highlight these significant advancements and their impact on the health-related outcomes for these animals.

In this Special Issue, we welcome contributions that shed light on various aspects of urology in animals, including, but not limited to, the following:

  • The etiology and pathogenesis of nephrological and urological disorders.
  • Advances in diagnostic imaging modalities such as ultrasound, computed tomography (CT), and magnetic resonance imaging (MRI) in nephrological and urological diseases.
  • The application of various therapeutic approaches for the management of nephrological and urological conditions in dogs and cats.
  • The management of chronic nephrological and urological conditions.

This Special Issue provides a comprehensive overview of the latest research and clinical developments in the field. By highlighting emerging trends, diagnostic tools, and therapeutic strategies, this collection aims to support veterinary professionals in the diagnosis, treatment, and management of nephrological and urological disorders in companion animals, ultimately enhancing patient care and outcomes. We aim to highlight these significant advancements and their impact on health-related outcomes for these animals.

We welcome submissions in the form of original research articles, reviews, brief communications, and case reports. Manuscripts can be submitted until the deadline and will undergo peer review upon receipt.

We look forward to your contributions to this important and evolving field of research.

Prof. Dr. Joseph Bartges
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • small animals
  • nephrology, urology
  • urinary tract disorders

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  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

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Research

16 pages, 407 KiB  
Article
Neutrophil Gelatinase-Associated Lipocalin (NGAL) as a Biomarker of Acute Kidney Injury (AKI) in Dogs with Congestive Heart Failure (CHF) Due to Myxomatous Mitral Valve Disease (MMVD)
by Maria Chiara Sabetti, Sabrina Fasoli, Serena Crosara, Cecilia Quintavalla, Giovanni Romito, Roberta Troìa, Francesca Fidanzio, Chiara Mazzoldi, Erica Monari and Francesco Dondi
Animals 2025, 15(11), 1607; https://doi.org/10.3390/ani15111607 - 30 May 2025
Viewed by 202
Abstract
Dogs with acute congestive heart failure (CHF) can develop acute kidney injury (AKI); the prevalence of this condition has not been defined. This study aimed to assess the occurrence of AKI (increase in serum creatinine (sCr) ≥ 0.3 mg/dL) within 48 h from [...] Read more.
Dogs with acute congestive heart failure (CHF) can develop acute kidney injury (AKI); the prevalence of this condition has not been defined. This study aimed to assess the occurrence of AKI (increase in serum creatinine (sCr) ≥ 0.3 mg/dL) within 48 h from admission in dogs with myxomatous mitral valve disease (MMVD) with acute CHF, and the role of urinary neutrophil gelatinase-associated lipocalin (uNGAL) as a predictive marker of AKI. This was a multicentric, prospective observational study. Thirty dogs were included. The types and dosages of the diuretics administered, as well as the serum and urinary chemistry, including uNGAL and uNGAL, to the urinary creatinine ratio (uNGALC), were determined at admission (T0) and after 24 (T24) and 48 (T48) hours of hospitalization. Nineteen dogs developed AKI. We found no statistically significant differences in sCr, uNGAL, uNGALC, diuretic dosage, or hours of hospitalization between dogs that developed AKI and those that did not. The urinary NGAL and uNGALC values were not statistically significantly different at any time point, while the sCr was higher at T24 and T48 than T0. Our findings suggest that AKI in MMVD dogs with CHF is primarily functional, driven by effective decongestion rather than severe tubular damage, with the benefits of decongestion outweighing transient increases in sCr. Full article
(This article belongs to the Special Issue Advances in Canine and Feline Nephrology and Urology)
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19 pages, 1047 KiB  
Article
Antimicrobial Resistance in Companion Animals: A 30-Month Analysis on Clinical Isolates from Urinary Tract Infections in a Veterinary Hospital
by Raffaele Scarpellini, Silvia Piva, Erika Monari, Kateryna Vasylyeva, Elisabetta Mondo, Erika Esposito, Fabio Tumietto and Francesco Dondi
Animals 2025, 15(11), 1547; https://doi.org/10.3390/ani15111547 - 25 May 2025
Viewed by 288
Abstract
Bacterial urinary tract infections (UTIs) are common in small animal practice and their inappropriate treatment contributes to the antimicrobial resistance (AMR) spreading. This study assessed bacterial prevalence, non-susceptibility percentages, antimicrobial prescription and the impact of the application of international guidelines redacted by the [...] Read more.
Bacterial urinary tract infections (UTIs) are common in small animal practice and their inappropriate treatment contributes to the antimicrobial resistance (AMR) spreading. This study assessed bacterial prevalence, non-susceptibility percentages, antimicrobial prescription and the impact of the application of international guidelines redacted by the International Society for Companion Animals Infectious Disease (ISCAID) in dogs and cats with UTIs evaluated at a European veterinary university hospital, over a 30-month period. A total of 729 bacterial isolates were included. The most frequently isolated bacterial species was Escherichia coli in both dogs (52.8%) and cats (45.7%). Following ISCAID guidelines, almost half of the cases were classified as upper UTIs (24.9%) or recurrent cystitis (24.8%). Multidrug resistance (MDR) percentage was 37.3% (n = 272). Over five semesters, MDR significantly decreased (p = 0.001). Additionally, a significant decrease was recorded for specimens from patients previously treated (p = 0.018) and under treatment at sampling (p < 0.001). Previous treatment with amoxicillin-clavulanate (p = 0.001), marbofloxacin (p < 0.001), enrofloxacin (p < 0.001) and piperacillin-tazobactam (p = 0.016) was linked with higher MDR rates. This study highlighted that companion animals are potential reservoirs for AMR; moreover, international guidelines applied in the daily practice guiding antimicrobial stewardship can lead to a reduction in AMR over time. Full article
(This article belongs to the Special Issue Advances in Canine and Feline Nephrology and Urology)
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