Special Issue "The Future of Antibiotics in Farm Animal Production Systems"
Deadline for manuscript submissions: closed (30 June 2019).
Interests: Cattle; lameness; welfare; reproduction; mastitis; micronutrients
Antimicrobial resistance has been described as potentially causing the end of modern medicine and England’s Chief Medical Officer has warned of the “post-antibiotic apocalypse”. The spotlight has fallen on the use of antibiotics in farm animals and how that use has impacted on the development of antimicrobial resistance in human patients. The most recent of these is the development of resistance to colistin which has been linked to its use on pig farms in China. Ironically, colistin, which is an antibiotic that was first used almost 60 years, has only recently become important in humans because, despite being both nephro- and neurotoxic, it is one of the last-resort antibiotics for treating multidrug-resistant bacteria such Pseudomonas aeruginosa
Antibiotics have a long history in farm animals. For example, penicillin was first used in people in 1942; within three years it was being used to treat mastitis in dairy cows. Unfortunately, so does antimicrobial resistance with the first report of “resistance of chronic staphylococcic bovine mastitis to massive penicillin therapy” occurring in 1947. Nevertheless, penicillin is still an effective treatment for bovine mastitis more than 70 years after it was first used; similarly cloxacillin, which was first used more than 50 years ago in dry cows, is still an effective means of treating subclinical mastitis at drying off.
Since the introduction of sulphonamides and penicillin there has been a huge expansion in the range and number of antibacterials available in human medicine. Many of those have become available on farm, so we have far more options for treating and preventing disease than we did even 20 years ago. This is undoubtedly a good thing from an animal welfare perspective—better antibiotics lead to higher cure rates. However, the pipeline of new antibiotics is drying up and we need to better preserve those antibiotics that we have, by better management of their use. Additionally, irrespective of the arguments about the importance of antibiotic use in farm animals as a source of resistant bacteria for humans we need to be seen to managing antibiotic use more effectively and more carefully on farms.
The theme of this Special Issue is the future use of antibiotics on farm. Where are we going to be in 20 years’ time, will that be where we want to be and how are we going to get there? These are the key questions that need answering. Or to put it another way: How can we reduce, refine and replace antibiotic use? We encourage you to submit papers which answer or attempt to answer any of those questions
Dr. Richard Laven
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Farm animals
- Antimicrobial resistance