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Plant Bioactives for Improving Health and Sustainability in Livestock Production Systems

A Special Issue of Animals (ISSN 2076-2615) belonging to the section "Animal Nutrition".

Deadline for manuscript submissions: 30 November 2026 | Viewed by 777

Editors


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Guest Editor
Department of Wildland Resources, Utah State University, 5230 Old Main Hill, Logan, UT 84322-5230, USA
Interests: foraging behavior; plant-herbivore interactions; landscape Interventions; diet selection; animal health and self-medication; rangelands; environmental impact; sustainability
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Wildland Resources, Utah State University, 5230 Old Main Hill, Logan, UT 84322-5230, USA
Interests: foraging behavior; plant-herbivore interactions; animal health; diet selection; rangelands; environmental impact; sustainability

E-Mail Website
Guest Editor
Department of Biological Sciences, State University of New York Albany, Albany, NY 12222, USA
Interests: sustainability; soil health; agricultural ecology; ecosystem services; land-use change; regenerative livestock production

Special Issue Information

Dear Colleagues,

This Special Issue focuses on how plant-derived bioactives, such as polyphenols, terpenes, and saponins, can be harnessed through grazing management, forage diversity, and diet formulation to improve animal health and productivity while enhancing sustainability in livestock production systems. We welcome the submission of mechanistic and applied studies across species, with particular relevance to grazing ruminants, that clarify effects on diet selection and feeding behavior, rumen fermentation and microbiome function, nutrient-use efficiency, and immune, antioxidant, and metabolic responses.

Submissions that connect plant bioactives to environmental performance are encouraged, including life-cycle assessment, greenhouse gas and nutrient loss outcomes, ecosystem services, and soil carbon dynamics. We also welcome research exploring links to human health and food quality, including how soil–plant–animal interactions influence product composition and system resilience. By integrating fundamental mechanisms with field-scale evidence and management-ready strategies, this issue aims to identify research gaps and priorities for future directions that can translate plant bioactives into practical programs to enhance animal health, welfare, and productivity while improving system sustainability and food quality, with potential benefits for consumer health.

Prof. Dr. Juan J. Villalba
Dr. Fred Provenza
Dr. Gary Kleppel
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Animals is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • plant bioactives
  • phyto-components
  • secondary metabolites
  • ruminants
  • grazing
  • animal health
  • human health
  • soil health
  • product quality
  • nutrient-use efficiency
  • ecosystem services
  • environmental impact.

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Published Papers (1 paper)

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Review

41 pages, 1158 KB  
Review
Applications and Action Mechanisms of Yucca schidigera Extract in Livestock, Poultry and Aquatic Animals
by Shiqi Xue, Qiwei Liu, Jingrong Feng, Yang Feng, Huijin Jia, Lanlan Yi, Sumei Zhao and Junhong Zhu
Animals 2026, 16(15), 2376; https://doi.org/10.3390/ani16152376 - 3 Aug 2026
Viewed by 436
Abstract
Yucca schidigera extract (YSE) is a plant-derived feed additive rich in steroidal saponins, polyphenols, and polysaccharides, with demonstrated anti-inflammatory, antioxidant, antibacterial, and ammonia-binding properties. This review systematically synthesizes the major bioactive components, core mechanisms of action, including modulation of the Nrf2/ARE and NF-κB [...] Read more.
Yucca schidigera extract (YSE) is a plant-derived feed additive rich in steroidal saponins, polyphenols, and polysaccharides, with demonstrated anti-inflammatory, antioxidant, antibacterial, and ammonia-binding properties. This review systematically synthesizes the major bioactive components, core mechanisms of action, including modulation of the Nrf2/ARE and NF-κB pathways, regulation of ruminal fermentation and ammonia-nitrogen metabolism, and maintenance of intestinal barrier integrity, and the species-specific application effects of YSE in pigs, poultry, ruminants, and aquatic animals. Most studies have shown that YSE can improve growth performance, reproductive efficiency, and product quality while concurrently reducing ammonia and methane emissions. However, the magnitude and consistency of these benefits vary considerably across species, dosage, and experimental conditions, with most evidence derived from controlled trials rather than commercial-scale validation. By integrating cross-species dose–response data and identifying critical knowledge gaps, including product standardization, long-term safety, and economic feasibility under commercial conditions, this review provides a theoretical and practical foundation for the evidence-based application of YSE as a sustainable feed additive. In the context of global efforts to reduce antibiotic use and mitigate environmental pollution from livestock production, YSE represents a promising, multifunctional tool for advancing ecological and low-carbon animal husbandry. Full article
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