Genetic Resource Evaluation and Germplasm Innovation of Poultry

A special issue of Agriculture (ISSN 2077-0472). This special issue belongs to the section "Farm Animal Production".

Deadline for manuscript submissions: 20 December 2025 | Viewed by 726

Special Issue Editors


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Guest Editor
National Engineering Laboratory for Animal Breeding, College of Animal Science and Technology, China Agricultural University, Beijing 100193, China
Interests: hen breeding; genetic mechanism analysis; disease resistance breeding; feather color; healthy farming

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Guest Editor
College of Animal Science and Technology, Hebei Agricultural University, Baoding 071001, China
Interests: quantitative genetics; genomics; molecular markers; egg quality; eggshell ultrastructure; biomineralization

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Guest Editor
College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, China
Interests: quantitative genetics; duck; chicken; reproductive traits; biological breeding; genome editing; fat deposition

Special Issue Information

Dear Colleagues,

Poultry species, such as chickens, ducks, geese, and turkeys, provide humans with a vital source of protein. These avian species exhibit a rich genetic and phenotypic diversity due to their large populations and high reproductive capacity. Multi-omics technologies, including genomics, transcriptomics, proteomics, and epigenetics, support the exploration of trait formation, yet there remains debate over the regulatory mechanisms of phenotypic traits.

This Special Issue focuses on the phenotypic diversity and characterization methods of poultry traits; the identification, function, and role of key candidate genes in trait regulation; the contribution of the polygene hypothesis and related models to the formation of poultry traits; and the latest advancements and discoveries in the epigenetic analysis of poultry traits. We aim to provide an overview and discussion on these topics, hoping to offer insights that will enrich and deepen our understanding of the regulatory mechanisms behind livestock phenotypic traits.

This journal particularly welcomes articles that present viewpoints and reviews, with the intention of enhancing and expanding the regulatory mechanisms of livestock phenotypic traits.

Prof. Dr. Zhonghua Ning
Prof. Dr. Dehe Wang
Dr. Long Liu
Guest Editors

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Keywords

  • phenotypic characterization
  • polygene hypothesis
  • regulatory mechanisms
  • epigenetic

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Published Papers (1 paper)

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Research

24 pages, 4611 KiB  
Article
Combined Genomic and Transcriptomic Screening of Candidate Genes for Asymmetric Oviduct Development in Hens
by Ruijie Li, Xiang Song, Xiao Lin, Mingli Deng, Yin Liu, Tuoyu Geng, Daoqing Gong, Minmeng Zhao and Long Liu
Agriculture 2025, 15(12), 1245; https://doi.org/10.3390/agriculture15121245 - 7 Jun 2025
Viewed by 471
Abstract
Background: While the mechanism of asymmetric gonadal development is generally understood, the mechanism of asymmetric oviduct development remains unclear. Methods: Right and left oviducts were collected from chick embryos at three developmental stages (Embryonic day 7.5, E9.5, and E11.5) for RNA-seq analysis (RNA-seq). [...] Read more.
Background: While the mechanism of asymmetric gonadal development is generally understood, the mechanism of asymmetric oviduct development remains unclear. Methods: Right and left oviducts were collected from chick embryos at three developmental stages (Embryonic day 7.5, E9.5, and E11.5) for RNA-seq analysis (RNA-seq). Whole-genome resequencing (WGRS) was performed on hens with bilateral reproductive systems (a rare natural occurrence) and unilateral controls. These data were co-analyzed with public RNA-seq data of female embryonic gonads at different developmental stages (E4.5, E5.5, and E6.5) to screen for candidate genes affecting oviduct degeneration/development. Results: RNA-seq analyses showed that a total of 27, 10, and 38 DEGs were identified between the left and right oviducts at E7.5, E9.5, and E11.5, respectively. WGRS analyses revealed 1045 differentially mutated genes (DMGs) between bilateral (D) and unilateral (S) groups. Preliminary validation highlighted BMP7, PAK3, SLC6A11, PITX2, and SMC1B as candidate genes influencing oviduct asymmetry. Conclusions: This study provides insights into the genetic basis of asymmetric oviduct development and lays the groundwork for breeding hens with bilateral reproductive systems. Full article
(This article belongs to the Special Issue Genetic Resource Evaluation and Germplasm Innovation of Poultry)
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