Journal Description
Surgeries
Surgeries
is an international, peer-reviewed, open access journal on findings and developments in surgery published quarterly online by MDPI. The Academy of Surgical Research (ASR) and the Italian Society of Hand Surgery (SICM) are affiliated with Surgeries and their members receive discounts on the article processing charges.
- Open Access— free for readers, with article processing charges (APC) paid by authors or their institutions.
- High Visibility: indexed within ESCI (Web of Science), Scopus, and other databases.
- Rapid Publication: manuscripts are peer-reviewed and a first decision is provided to authors approximately 24.4 days after submission; acceptance to publication is undertaken in 3.7 days (median values for papers published in this journal in the second half of 2025).
- Recognition of Reviewers: APC discount vouchers, optional signed peer review, and reviewer names published annually in the journal.
Impact Factor:
1.1 (2024);
5-Year Impact Factor:
1.0 (2024)
Latest Articles
Lymphadenectomy and Postoperative Complications in Stage III Melanoma: A Single-Center Analysis
Surgeries 2026, 7(1), 16; https://doi.org/10.3390/surgeries7010016 - 23 Jan 2026
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Background/Objectives: Over the last decade, the role and timing of lymph node dissection (LND) in stage III melanoma has shifted from completion LND after a positive sentinel node to a mainly therapeutic procedure for clinically evident nodal disease, driven by randomized evidence showing
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Background/Objectives: Over the last decade, the role and timing of lymph node dissection (LND) in stage III melanoma has shifted from completion LND after a positive sentinel node to a mainly therapeutic procedure for clinically evident nodal disease, driven by randomized evidence showing no survival benefit for routine completion dissection. In this evolving landscape, real-world data on postoperative morbidity—by nodal basin—and on whether complications may influence melanoma-specific survival (MSS) and disease-free survival (DFS) remain limited. We evaluated 90-day postoperative complications after cervical, axillary, and inguino–iliac–obturator LND and explored their association with survival outcomes and treatment era. Methods: We retrospectively analyzed 185 consecutive stage III melanoma patients undergoing LND at a single tertiary center (January 2004–August 2025). Postoperative morbidity was recorded up to 90 days and graded by Clavien–Dindo; given the very low rate of grade > II events, the primary endpoint was a composite of loco-regional surgical field–related complications (persistent seroma, wound dehiscence, surgical-site infection, limb lymphedema). Risk factors were assessed using logistic regression; Firth’s penalized models were applied when appropriate. MSS and DFS were estimated by Kaplan–Meier and explored with Cox models. Results: Median follow-up was 105 months. Surgical field–related complications occurred in 16.8% (31/185), and postoperative mortality was 1.0% (2/185). In multivariable analyses, inguino–iliac–obturator LND was associated with higher odds of overall complications (OR 4.03) and specifically wound dehiscence (OR 4.79) and infection (OR 7.18) versus axillary LND. MSS (n = 179) was 82% at 1 year, 55% at 5 years, and 49% at 10 years; DFS (n = 171) was 63%, 42%, and 41%, respectively. In era-based comparisons, nodal yield decreased in the post–MSLT-II period without clear separation of MSS/DFS curves; exploratory models did not show a consistent independent signal linking postoperative complications to MSS/DFS. Conclusions: In stage III melanoma, LND was associated with low major morbidity, but clinically meaningful locoregional complications persisted—most notably after inguino–iliac–obturator dissection. These data support careful patient selection and basin-tailored strategies to reduce groin morbidity within modern multidisciplinary management.
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Open AccessArticle
Long Term Results of Clinical Outcome and Patients’ Satisfaction After Modular Stem-Neck Hip Arthroplasty
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Panagiotis Karampinas, Periklis Pelantis, Evangelos Sakellariou, Ioannis Spyrou, Angelos Kontos, Elias S. Vasiliadis, John Vlamis and Spiros G. Pneumaticos
Surgeries 2026, 7(1), 15; https://doi.org/10.3390/surgeries7010015 - 22 Jan 2026
Abstract
Background: The primary concern of hip surgeons is restoring the physiological biomechanics of the hip joint through arthroplasty, thereby enabling patients with osteoarthritis to engage better in daily activities. The modularity of the femoral stem-neck head allows surgeons to better restore the hip’s
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Background: The primary concern of hip surgeons is restoring the physiological biomechanics of the hip joint through arthroplasty, thereby enabling patients with osteoarthritis to engage better in daily activities. The modularity of the femoral stem-neck head allows surgeons to better restore the hip’s native biomechanics. However, concerns have been raised regarding the potential postoperative complications. This study aims to evaluate patients’ satisfaction and functional outcomes following primary Total Hip Arthroplasty (THA) with modular stem-neck, with a mean follow-up duration of eight years. Methods: We retrospectively reviewed 208 patients who underwent primary THA with modular stem-neck between February 2012 and July 2019. The follow-up period extended from November 2024 to April 2025. Patients who died from unrelated causes were excluded. Patients’ satisfaction was assessed using the SF-36 questionnaire, while functional outcomes were evaluated using the Harris Hip Score (HHS). Intraoperative and postoperative complications were meticulously documented. Results: The average follow-up duration was 95.6 months, with a range from 67.7 to 159.7 months. The mean SF-36 score was 91.2 out of 100, indicating high patient satisfaction. The mean HHS was 90 out of 100, reflecting excellent functional outcomes. Notably, some patients achieved the maximum score of 100 in both SF-36 and HHS assessments, while the lowest recorded scores were 54 and 50, respectively. The mean age of patients at the time of surgery was 67.1 years. One case of periprosthetic fracture was reported; however, no complications related to modular necks, such as trunnionosis or implant failure, were observed. Conclusions: The present study demonstrates that modular neck primary THA could achieve excellent functional and radiological outcomes, high patient satisfaction, and outstanding long-term survivorship, provided that implant selection and surgical technique follow biomechanical principles.
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(This article belongs to the Special Issue Advances in Total Hip and Knee Arthroplasty)
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Open AccessArticle
Reaches of Unilateral Biportal Endoscopy in Lower Thoracic and Lumbar Spinal Extramedullary Tumor Resection: Case Series, Surgical Note, and Outcomes
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Adrian Sanchez-Gomez, Carlos Castillo-Rangel, Gustavo Alberto Vera-Perez, Malcom D. Prestonji, Rodolfo Guerrero-Perez and Gerardo Marín
Surgeries 2026, 7(1), 14; https://doi.org/10.3390/surgeries7010014 - 21 Jan 2026
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Background: Extramedullary spinal tumors represent a significant challenge for spine surgeons. Currently, various techniques exist to perform tumor resection safely while optimizing patient outcomes. Historically, the standard of care has been open surgery; however, in the last two decades, Minimally Invasive Spine
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Background: Extramedullary spinal tumors represent a significant challenge for spine surgeons. Currently, various techniques exist to perform tumor resection safely while optimizing patient outcomes. Historically, the standard of care has been open surgery; however, in the last two decades, Minimally Invasive Spine Surgery (MISS) techniques have gained importance due to superior postoperative recovery. Literature on Unilateral Biportal Endoscopy (UBE) for tumor resection is currently limited. We propose that UBE has the potential to become a standard approach for these lesions due to its distinct advantages. Methods: We performed a retrospective review of 11 patients who underwent UBE resection of lower thoracic and lumbar spinal extramedullary tumors. We analyzed clinical files and intraoperative endoscopic videos to describe our surgical technique step by step. We also evaluated the advantages of this approach in terms of resection rate, operative time, operative blood loss, and hospital stay. A representative case is also presented. Results: Clinical resolution and significant symptomatic improvement were achieved in all cases, as evidenced by functional and pain scales. In terms of tumor resection, we obtained results comparable to other MISS techniques and open surgery, with a low complication rate. Conclusions: UBE represents a safe, effective evolution in MISS for spinal tumors. Future studies with larger cohorts are needed to validate these findings as a standard of care.
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Open AccessCase Report
Successful Digital Replantation in a Resource-Limited Kenyan Hospital: A Case Report and Discussion
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Alfio Luca Costa, Luca Folini, Alvise Montanari and Franco Bassetto
Surgeries 2026, 7(1), 13; https://doi.org/10.3390/surgeries7010013 - 20 Jan 2026
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Replantation of an amputated finger is a complex microsurgical procedure that is rarely attempted in low-resource settings due to limited infrastructure and expertise. We report a case of complete amputation of a finger in rural Kenya that was successfully replanted during a humanitarian
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Replantation of an amputated finger is a complex microsurgical procedure that is rarely attempted in low-resource settings due to limited infrastructure and expertise. We report a case of complete amputation of a finger in rural Kenya that was successfully replanted during a humanitarian surgical mission. A 28-year-old man sustained a severe crush avulsion agricultural machine injury resulting in the amputation of all ten digits; only one digit was deemed suitable for replantation. The replantation was performed under loupe and microscope magnification by a visiting specialist team in collaboration with local staff. Intraoperatively, bony fixation with Kirschner wires, extensor and flexor digitorum profundus tendon repair, arterial and venous anastomoses, and neurorrhaphy of the digital nerve were achieved. Postoperatively, the finger survived with adequate perfusion. At one-month follow-up, the replanted finger was viable with progressing wound healing and early joint motion; further rehabilitation was arranged to maximize functional recovery. This case, which is, to our knowledge, one of the first documented digital replantations in East Africa, illustrates that successful microsurgical limb salvage is feasible in a non-specialized hospital setting. Our experience underscores that, with proper planning, training, and teamwork, advanced reconstructive procedures like finger replantation can be safely carried out even in resource-constrained hospitals, offering patients in low-income regions outcomes previously achievable only in high-resource centers.
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(This article belongs to the Section Hand Surgery and Research)
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Open AccessCase Report
Treatments of Polyethylene Tibial Post Fracture in Posterior Stabilized Knee Prosthesis with Unstable Total Knee Arthroplasty: A Case Series
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Jaehoon Kim, In-Soo Song and Jae-Beom Bae
Surgeries 2026, 7(1), 12; https://doi.org/10.3390/surgeries7010012 - 18 Jan 2026
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Background and Clinical Significance: With increasing demand for total knee arthroplasty (TKA), the incidence of post-operative instability has also risen. Although fracture of the polyethylene tibial post in posterior-stabilized (PS) prostheses is relatively uncommon, it should not be overlooked because delayed recognition may
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Background and Clinical Significance: With increasing demand for total knee arthroplasty (TKA), the incidence of post-operative instability has also risen. Although fracture of the polyethylene tibial post in posterior-stabilized (PS) prostheses is relatively uncommon, it should not be overlooked because delayed recognition may lead to severe late sequelae. Case Presentation: Between April 2008 and January 2020, 132 revision TKAs were performed at our institution due to suspected instability with or without component loosening. Among these, three patients were identified as having instability associated with fracture of the polyethylene tibial post in PS implants. All three patients presented late, with a mean interval of 49.66 months (range 34–74) after the index TKA. At presentation, all demonstrated multiplanar global instability, and two showed recurvatum deformity. Pre-operatively, revision surgery was indicated due to progressive global instability. Although tibial post fracture was suspected as a possible underlying cause, the diagnosis could not be definitively established until intraoperative inspection, which confirmed polyethylene tibial post fracture in all cases. Each patient underwent revision TKA using a semi-constrained prosthesis with an increased polyethylene insert height. At final follow-up (12–18 months), all patients achieved complete resolution of clinical instability and demonstrated meaningful improvement in the Hospital for Special Surgery (HSS) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores. Conclusions: Although rare, polyethylene tibial post fracture should be considered in the differential diagnosis of post-operative knee instability following PS TKA. Early recognition may allow management with isolated polyethylene exchange, whereas delayed diagnosis can result in progressive ligamentous insufficiency and global multiplanar instability, ultimately necessitating revision using a semi-constrained implant.
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(This article belongs to the Special Issue Advances in Total Hip and Knee Arthroplasty)
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Open AccessArticle
A Chronological Analysis of Fracture Surgery for Femoral Metastasis
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Jurina Izaki, Hirokazu Shimizu, Masatake Matsuoka, Tamotsu Soma, Daisuke Takahashi, Tomohiro Shimizu, Kanako Ito, Hiroaki Hiraga, Norimasa Iwasaki and Akira Iwata
Surgeries 2026, 7(1), 11; https://doi.org/10.3390/surgeries7010011 - 18 Jan 2026
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Background: The prognostic trends for adults who undergo fracture surgery for metastatic long bones remain unclear, even as survival among individuals with bone metastasis has improved. Because prognoses after fracture surgery may shift over time, this chronological study aimed to evaluate outcomes
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Background: The prognostic trends for adults who undergo fracture surgery for metastatic long bones remain unclear, even as survival among individuals with bone metastasis has improved. Because prognoses after fracture surgery may shift over time, this chronological study aimed to evaluate outcomes in individuals who received surgical treatment for femoral metastasis. Methods: This multicenter retrospective study included 186 adults who underwent fracture surgery for metastatic femoral disease between 2008 and 2023. Individuals were categorized into period 1 (2008–2016) and period 2 (2017–2023). The primary outcome was 1-year overall survival. Prognostic variables included fracture type (impending pathological fracture (IF) or completed pathological fracture (CF)), recovery of ambulation, and receipt of chemotherapy. Results: Individuals in period 2 were older and had a higher rate of solitary bone metastasis; however, period 2 did not demonstrate a higher proportion of IF relative to CF. Multivariate analysis showed that the hazard ratio for period 2 compared with period 1 was 0.57 (95% confidence interval: 0.35 to 0.94, p = 0.02). Conclusions: This chronological assessment demonstrated that the later period was associated with improved 1-year overall survival after fracture surgery for metastatic long bone disease. Because prophylactic fixation for IF is linked to more favorable outcomes, increasing the proportion of IF cases relative to CF should be prioritized.
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Open AccessArticle
Incidental Carcinomas and Lesions with Uncertain Malignant Potential (B3) Discovered During Symmetrization Mammoplasty in Breast Cancer Patients—Retrospective Single-Center Experience
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Daciana Grujic, Horia Cristian, Alis Dema, Mihai Iliescu Glaja, Teodora Hoinoiu, Fabiana Simion, Daniel Pit, Isabela Caizer-Găitan and Cristina Oprean
Surgeries 2026, 7(1), 10; https://doi.org/10.3390/surgeries7010010 - 4 Jan 2026
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Although occult breast carcinomas and lesions with uncertain malignant potential are rare, their incidental discovery during symmetrizing mammoplasty can significantly alter the treatment approaches and cancer staging. In the context of oncoplastic surgery, the systematic evaluation of the contralateral breast is a clinical
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Although occult breast carcinomas and lesions with uncertain malignant potential are rare, their incidental discovery during symmetrizing mammoplasty can significantly alter the treatment approaches and cancer staging. In the context of oncoplastic surgery, the systematic evaluation of the contralateral breast is a clinical priority that has been underexplored in Eastern Europe. Background/Objectives: This study aimed to assess the incidence and histological characteristics of incidental carcinomas and B 3 lesions detected during contralateral symmetry mammoplasty in patients with breast cancer. Methods: This retrospective study was conducted at the Plastic and Reconstructive Surgery Clinic of the “Pius Brînzeu” County Emergency Clinical Hospital in Timisoara, Romania, over six years (2018–2024), and included 180 of 256 patients who underwent contralateral breast symmetrization. Results: Among the 180 patients, 21 (11.66%) had incidental findings: eight (4.44%) had contralateral carcinomas, and 13 (7.22%) had B3 lesions. The histopathological types identified were invasive ductal carcinoma NST (one case), ductal carcinoma in situ (one case), invasive lobular carcinoma (five cases), and mucinous/papillary carcinoma (one case). Compared to the reported international range of 2–10%, our observed incidence of 11.66% reflects the unique aspects of our patient cohort and the thoroughness of our histological analyses. Conclusions: Detection of contralateral carcinomas and B3 lesions during symmetry mammoplasties underscores the importance of a multidisciplinary approach, comprehensive bilateral screening, and detailed histopathological examination of specimens.
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(This article belongs to the Special Issue State-of-the-Art Research and Emerging Innovations in Plastic and Aesthetic Surgery)
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Open AccessOpinion
Is Chronic Pelvic Sepsis Complicating Low Anterior Resection of Rectal Cancer Preventable?
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Elroy Patrick Weledji
Surgeries 2026, 7(1), 9; https://doi.org/10.3390/surgeries7010009 (registering DOI) - 1 Jan 2026
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The combination of anatomical inaccessibility, less-than-optimal blood supply, tightly closed anal sphincters below a low anastomosis, and an infected haematoma is likely to be contributory to anastomotic leakage following low anterior resection of the rectum for rectal cancer. Although under-reported, chronic pelvic sepsis
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The combination of anatomical inaccessibility, less-than-optimal blood supply, tightly closed anal sphincters below a low anastomosis, and an infected haematoma is likely to be contributory to anastomotic leakage following low anterior resection of the rectum for rectal cancer. Although under-reported, chronic pelvic sepsis complicating low anterior resection of the rectum is still a major problem associated with impaired quality of life. It should be avoided as much as possible, in addition to the fact that it is more difficult to manage surgically than acute sepsis. Primary preventive measures are well established. Secondary prevention of chronic pelvic sepsis is achieved by early diagnosis and active management of the anastomotic leak. However, optimal postoperative management cannot fully eliminate chronic sinuses or delayed reactivation leaks. With chronic leakage, major restorative redo-anastomosis or ablative abdominal perineal resection is required and 20% of patients will require a permanent stoma.
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Open AccessTechnical Note
Use of the Vascularized Fascial Flap Based on the 1,2 ICSRA Artery for Scapholunate Ligament Repair: An Anatomic Study
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Enrico Palombo, Simone Otera, Yuri Piccolo, Stefano Gumina, Diego Ribuffo and Alessia Pagnotta
Surgeries 2026, 7(1), 8; https://doi.org/10.3390/surgeries7010008 - 1 Jan 2026
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Scapholunate (SL) ligament injuries, if not properly treated, can compromise wrist biomechanics, leading to instability, scapholunate advanced collapse (SLAC) and progressive osteoarthritis. Depending on the severity of the injury, current repair techniques include either arthroscopic or open surgical approaches; however, the limited vascularization
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Scapholunate (SL) ligament injuries, if not properly treated, can compromise wrist biomechanics, leading to instability, scapholunate advanced collapse (SLAC) and progressive osteoarthritis. Depending on the severity of the injury, current repair techniques include either arthroscopic or open surgical approaches; however, the limited vascularization of the region often represents an obstacle to optimal ligament healing. This study aims to assess the feasibility of using a vascularized fascial flap based on the 1,2 intercompartmental supraretinacular artery (1,2 ICSRA) for biological augmentation of the scapholunate ligament. Five previously injected cadaveric upper limbs were dissected and flap dimensions, including length, width, and pedicle length, were measured using a millimeter-calibrated ruler by two independent operators. All flaps provided sufficient coverage, and the vascular pedicle length allowed tension-free positioning without vascular kinking. These findings demonstrate that a 1,2 ICSRA-based fascial flap is anatomically feasible for scapholunate ligament augmentation. It should be noted that this is a purely cadaveric study, and the technique has not yet been tested in vivo. The results suggest potential surgical applications, providing a vascularized biological option that may enhance ligament healing in future clinical studies.
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(This article belongs to the Special Issue Feature Papers in Hand Surgery and Research)
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Open AccessReview
Biomechanics, Material Performance, and Wear Analysis in Total Hip Arthroplasty: A Review
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Nishant Nikam, Satish Shenoy B., Sawan Shetty, Shyamasunder Bhat N., Laxmikant G. Keni, Chethan K. N. and Şenay Mihçin
Surgeries 2026, 7(1), 7; https://doi.org/10.3390/surgeries7010007 - 30 Dec 2025
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Total hip arthroplasty (THA) is a transformative procedure for managing severe hip disorders, yet implant longevity remains a critical challenge, particularly for younger, active patients. Wear-related complications are a leading cause of revision surgery, emphasizing the need for optimized design and material performance.
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Total hip arthroplasty (THA) is a transformative procedure for managing severe hip disorders, yet implant longevity remains a critical challenge, particularly for younger, active patients. Wear-related complications are a leading cause of revision surgery, emphasizing the need for optimized design and material performance. This systematic review aims to synthesize evidence on the wear behavior, material properties, and design parameters of hip implants with a focus on finite element analysis (FEA)-based predictive approaches. A comprehensive literature search was conducted across Scopus, PubMed, ScienceDirect, MDPI, and Cochrane databases following PRISMA guidelines. Studies published between 2010 and 2025 were included if they addressed THA biomechanics, wear analysis, or material optimization using FEA, hip simulators, or radiostereometric techniques. Key findings reveal that larger femoral heads, while reducing contact pressure, increase wear due to greater sliding distance. Gravimetric wear rates ranged from 3.15 ± 0.27 mg/Mc to 2.18 ± 0.31 mg/Mc, while linear and volumetric wear reached 0.0375 mm/Mc and 33.6 mm3/Mc, respectively. Stress analysis showed custom stems exhibited markedly lower von Mises stress (194.9 MPa) compared to standard designs (664.3 MPa), and fatigue assessments confirmed a factor of safety > 1 across profiles. Patient-specific factors, such as body weight, significantly influenced wear with a 26% increase in metal wear observed between 100 kg and 140 kg. This systematic review synthesizes current research on total hip arthroplasty, emphasizing biomechanical and material factors critical for implant longevity and patient care. It uniquely integrates FEA-based wear prediction with clinical implications, bridging computational modeling, geometry optimization, and material performance to provide actionable insights for next-generation, patient-specific hip implant design.
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Open AccessCase Report
Primary Trapeziometacarpal (TMC) Arthroplasty for Bennett Fracture in Setting of Severe Thumb Osteoarthritis: A Case Report
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Chiara Stambazzi, Marvin Menini and Luca Pandolfo
Surgeries 2026, 7(1), 6; https://doi.org/10.3390/surgeries7010006 - 26 Dec 2025
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Bennett fractures are common intra-articular fractures of the base of the first metacarpal. Not optimal restoration of the articular surface often leads to osteoarthritis, with pain and limited movement. In patients with established and symptomatic TMC osteoarthritis, arthroplasty with MAIA® prosthesis could
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Bennett fractures are common intra-articular fractures of the base of the first metacarpal. Not optimal restoration of the articular surface often leads to osteoarthritis, with pain and limited movement. In patients with established and symptomatic TMC osteoarthritis, arthroplasty with MAIA® prosthesis could be a valid option. In July 2024, a right-handed man of 68 years old fell on his hand. Radiographs showed a Bennett fracture in a setting of Eaton–Littler stage 3 osteoarthritis, already painful and disabling according to the patient. For correct pre-operative planning, a 3D model of the affected hand was produced. The patient underwent TMC arthroplasty with a MAIA® prosthesis. Two months after surgery, the results reported no pain (VAS scale) and considerable functionality and mobility of the first ray (AROM, Kapandji score, and PRWHE were investigated). The mean pinch strength of the right hand was 7 kg and of the left hand 7.5 kg using a pinch meter. At one-year follow-up, no complications were reported: the implant did not show signs of loosening or subsidence. TMC arthroplasty in Bennett fractures could represent a safe procedure in patients with established TMC osteoarthritis; however, further studies are requested in order to clarify effectiveness and indications.
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(This article belongs to the Special Issue Digital Technologies in Hand Surgery: Ultrasound, 3D Printing, Planning & Robotics)
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Open AccessArticle
Laparoscopic Repair of Primary Ventral Hernias: Outcomes of a Retrospective Cohort Study on 200 Surgeries Using Single Mesh and IPOM Technique
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Gaetano Vetrone, Luca Negosanti, Rossella Sgarzani and Michele Masetti
Surgeries 2026, 7(1), 5; https://doi.org/10.3390/surgeries7010005 - 25 Dec 2025
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Background: Primary ventral hernias (PVHs) are a frequent disease that can impair quality of life. Laparoscopic intraperitoneal onlay mesh (IPOM) technique has shown good outcomes in appropriately selected cases. Methods: We report the results of a retrospective analysis involving 200 consecutive patients who
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Background: Primary ventral hernias (PVHs) are a frequent disease that can impair quality of life. Laparoscopic intraperitoneal onlay mesh (IPOM) technique has shown good outcomes in appropriately selected cases. Methods: We report the results of a retrospective analysis involving 200 consecutive patients who underwent laparoscopic ventral hernia repair with a standardized technique using a single mesh from January 2011 to September 2024 to define the safety of laparoscopy in ventral hernia treatment. Results: The study included 147 umbilical hernias (73%) and 53 epigastric hernias (27%). The average defect measured 3 cm, with sizes ranging from 2 to 7 cm. After a mean follow-up of 1708 days (range 117–4642), no complications associated with the mesh were observed; there was only one (0.5%) recurrence documented and no bulging was observed. Conclusions: Laparoscopic repair of PVH using a standardized technique and using the same mesh, which has been proven safe over the last 15 years, offers good results.
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Open AccessArticle
Shock Wave-Induced Regeneration in Soft Tissue Reconstruction: Clinical Application in Hand Surgery
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Luciana Marzella, Michele Riccio, Maria Cristina D’Agostino, Alberto Lazzerini and Francesco De Francesco
Surgeries 2026, 7(1), 4; https://doi.org/10.3390/surgeries7010004 - 25 Dec 2025
Abstract
Background/Objectives: Chronic ulcers are often characterized by impaired microcirculation, delayed epithelialization, and persistent pain. Extracorporeal shock wave therapy (ESWT) has emerged as a regenerative approach capable of modulating angiogenesis and tissue repair. This study aimed to evaluate the effects of ESWT on
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Background/Objectives: Chronic ulcers are often characterized by impaired microcirculation, delayed epithelialization, and persistent pain. Extracorporeal shock wave therapy (ESWT) has emerged as a regenerative approach capable of modulating angiogenesis and tissue repair. This study aimed to evaluate the effects of ESWT on wound healing, microvascular remodeling, sensory recovery, and joint mobility in patients with chronic ulcerative lesions. Methods: In this prospective observational study, patients with chronic ulcers underwent a standardized ESWT protocol in addition to conventional wound care. Clinical outcomes were assessed at baseline and at the end of follow-up using the Bates–Jensen Wound Assessment Tool (BWAT), pain visual analogue scale (VAS), capillaroscopy, Semmes–Weinstein monofilament test (SWMT), two-point discrimination (2PD), and range of motion (ROM). Results: ESWT was associated with a significant improvement in wound status, pain, sensory function, and ROM. Capillaroscopy showed robust correlations with clinical recovery, inversely with BWAT (ρ = −0.64, p < 0.01), SWMT (ρ = −0.55, p < 0.05), and 2PD (ρ = −0.49, p < 0.05), and positively with ROM recovery (ρ = 0.58, p < 0.01). Diabetic and smoking patients required a longer healing period (5.8 ± 1.3 weeks) than non-diabetic, non-smoking patients (4.2 ± 0.9 weeks, p = 0.03), although BWAT, capillaroscopy, and ROM values converged by week 8. Conclusions: ESWT was associated with meaningful structural, microvascular, and functional improvements in chronic ulcers. Microvascular remodeling, assessed by capillaroscopy, emerged as a key correlate of clinical recovery. Despite slower early healing in diabetic and smoking patients, final regenerative outcomes were ultimately comparable across risk profiles.
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(This article belongs to the Special Issue Feature Papers in Hand Surgery and Research)
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Open AccessArticle
Augmentation and Increased Projection of Buttocks with a Sofiderm® Cross-Linked Hyaluronic Acid Filler: A Deep and Superficial Implantation Technique
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Giordano Vespasiani, Giuseppina Ricci, Simone Michelini, Federica Trovato, Antonio Di Guardo, Lorenzo Califano, Laura Nesticò, Stefania Guida and Giovanni Pellacani
Surgeries 2026, 7(1), 3; https://doi.org/10.3390/surgeries7010003 - 25 Dec 2025
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Background: In recent years, hyaluronic acid filler for the restoration and increase in buttock volume has been a procedure that has seen increasing success, both thanks to the considerable increase in patient demand and thanks to the improvement of implant techniques and device
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Background: In recent years, hyaluronic acid filler for the restoration and increase in buttock volume has been a procedure that has seen increasing success, both thanks to the considerable increase in patient demand and thanks to the improvement of implant techniques and device manufacturing technologies. Aims: The primary objective of this pilot study is to demonstrate the validity of an innovative filler inoculation technique in the upper quadrants of the buttocks and in the supra- and subfascial area in order to optically restore the appearance of a pleasant lumbar lordosis and to lift the upper quadrants with reduction in the infragluteal fold. The secondary objective is to evaluate the safety and efficacy of Sofiderm SubSkin® (Techderm Biological Products Co., Ltd., Hangzhou, China), a highly versatile hyaluronic acid filler, formulated with a rheology suitable for use on the face and body. Patients/Methods: Five female subjects (50–63 years) were subjected to gluteal fillers in the supra- and subfascial areas; the correct positioning of the filler was investigated by means of a 20 Mhz ultrasound probe. Results: All patients obtained a significant improvement in the projection of the upper part of the buttocks. The implantation technique and the optimal rheological properties of the device brought about a natural and well-defined increase in volume, with a projection of the upper part of the buttocks and a consequent lifting of the lower parts and reduction in the length of the infragluteal fold. Conclusions: This study confirmed the efficacy and safety of the cross-linked hyaluronic acid Sofiderm Derm SubSkin® in increasing the projection of the upper part of the buttocks, using an innovative mixed implantation technique, in a sample of selected patients.
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Open AccessArticle
Immediate Postoperative Biofeedback with an Insole Device in Unilateral TKA
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Daniel Pfeufer, Mike B. Anderson, Jeremy Gililland, Robert Hube, Christoph Linhart, Julius Brendler and Christopher E. Pelt
Surgeries 2026, 7(1), 2; https://doi.org/10.3390/surgeries7010002 - 23 Dec 2025
Abstract
Background: After unilateral total knee arthroplasty (TKA), patients place more weight on the nonsurgical limb than the surgical limb. The objective of this study was to determine the possibility of providing live biofeedback during early recovery of patients undergoing unilateral TKA and to
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Background: After unilateral total knee arthroplasty (TKA), patients place more weight on the nonsurgical limb than the surgical limb. The objective of this study was to determine the possibility of providing live biofeedback during early recovery of patients undergoing unilateral TKA and to determine the necessary sample size for future trials. Methods: Twenty patients with unilateral TKA were randomized into two groups: a feedback group and a control group. Inclusion criteria included no contralateral knee pain and aid-free walking before surgery. There were 8 patients in the feedback group and 10 in the control group. Compliance with the recommended training was 91%. The feedback group trained with an insole device for 15 min a day for 4 weeks, along with normal physiotherapy. The control group received normal physiotherapy only. Gait parameters were recorded on level ground at two and six weeks. The primary outcome was the percent loading rate. The secondary outcomes included gait speed, cadence, percent peak force, and pain. Results: Patients within the feedback group showed a small, non-significant trend toward a higher precent load rate at 6 weeks compared to the control group in level walking (p = 0.92). Conclusions: Our findings indicate that live biofeedback on a gait parameter, like percent load rate, can be provided by the mentioned system and may support immediate changes in gait parameters. The compliance of 91% with training and no reported adverse events indicates that the system was easy to use. Following TKA, there may be a potential exploratory use of mobile, real-time biofeedback to help address gait abnormalities and accelerate rehabilitation. This clinical trial was registered at clinicaltrials.gov (Identifier: NCT03673293) on 14 September 2018. This study was conducted in accordance with the Declaration of Helsinki and approved by the institutional review board of the University of Utah (IRB_00110935) on 10 September 2018.
Full article
(This article belongs to the Special Issue Advances in Total Hip and Knee Arthroplasty)
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Open AccessArticle
The “Bank Finger” Principle in Hand Surgery—Retrospective Study vs. Systematic Review
by
Mihaela Pertea, Mihai-Codrin Constantinescu, Andra-Irina Bulgaru-Iliescu, Stefana Avadanei-Luca, Dan Cristian Moraru, Bogdan Veliceasa, Alexandru Filip, Claudiu Carp and Alexandru-Hristo Amarandei
Surgeries 2026, 7(1), 1; https://doi.org/10.3390/surgeries7010001 - 23 Dec 2025
Abstract
Background/Objectives: The “bank-finger” or “spare-parts” principle offers an immediate reconstructive solution in mutilating hand injuries by repurposing viable tissues from non-salvageable digits to restore length, coverage, and function. Although described for decades, systematic evidence remains scarce. This study compared a single-center retrospective cohort
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Background/Objectives: The “bank-finger” or “spare-parts” principle offers an immediate reconstructive solution in mutilating hand injuries by repurposing viable tissues from non-salvageable digits to restore length, coverage, and function. Although described for decades, systematic evidence remains scarce. This study compared a single-center retrospective cohort with a systematic review of the specialized literature (2015–2025) to clarify the indications, reconstructive models, assessment of functional outcomes, and complication profiles associated with this technique. Methods: A retrospective analysis was performed on 35 adult patients treated for complex hand trauma between 2017 and 2024. It was compared with a systematic review of nine clinical studies identified across PubMed, Scopus, Embase, Web of Science, and Cochrane Library. Extracted variables included demographics, mechanisms of injury, type of tissues transferred, vascularization method, complications, and functional outcomes. Methodological quality was assessed using the Joanna Briggs Institute (JBI) criteria for case reports and case series. Results: Across 78 cases (43 from the literature and 35 institutional), vascularized fillet and osteo-cutaneous transfers constituted the predominant reconstructive approach, providing immediate skeletal stability and durable, sensate soft-tissue coverage. All flaps and grafts survived, and functional recovery was consistently favorable. In the retrospective cohort, standardized evaluation demonstrated excellent outcomes (mean DASH 14.6, MHQ 82.5, VAS 1.8). The overall complication rate remained below 10%, limited to transient venous congestion or mild postoperative stiffness. No infections, flap losses, or donor-site morbidity were reported. Conclusions: The bank-finger technique is a reliable, biologically efficient reconstructive strategy for acute mutilating hand trauma. When applied early and with appropriate tissue selection, it achieves outcomes comparable to conventional microsurgical options while avoiding additional donor-site morbidity. The present combined analysis highlights its reproducibility and underscores the need for prospective multicenter studies employing standardized functional metrics.
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(This article belongs to the Section Hand Surgery and Research)
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Open AccessArticle
Postoperative Blood Pressure Does Not Affect Lactate Clearance in Cardiac Surgery: A Retrospective Observational Cohort Study
by
James Hall, George Elkomos-Botros and Michael Khilkin
Surgeries 2025, 6(4), 112; https://doi.org/10.3390/surgeries6040112 - 17 Dec 2025
Abstract
Background: Tight blood pressure control is a cornerstone of postoperative cardiac surgery patients. In addition, plasma lactate levels are frequently monitored in this setting as it is a marker for malperfusion, with early elevated levels being associated with increased morbidity and mortality. Elevations
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Background: Tight blood pressure control is a cornerstone of postoperative cardiac surgery patients. In addition, plasma lactate levels are frequently monitored in this setting as it is a marker for malperfusion, with early elevated levels being associated with increased morbidity and mortality. Elevations from malperfusion may be due to decreased cardiac output, hypovolemia, or persistent post-bypass vasoplegic response. Here, we investigate whether lower blood pressures, significant changes from baseline, and cardiac perfusion pressures delay the clearance of lactate after cardiac surgery. Methods: This is a retrospective cohort observational study of patients who have undergone coronary artery bypass graft (CABG) and valve replacement or repair surgeries at NYU Langone Long Island Hospital over a 6-month period. Postoperative blood pressures and lactate levels were examined over the first 16 h of care. Primary outcome: The relationship between blood pressure parameters and lactate clearance. Secondary outcomes: ICU length of stay, hospital length of stay, and mortality. Results: A total of 81 patients met inclusion criteria. The average pre-operative mean arterial blood pressure (MAP) was 95.4 mmHg and the average MAP in the first 6 h post-operatively was 78.4 mmHg. The average change in MAP from baseline was a decrease of 16.7%. The average cleared lactate fraction by 16 h postoperatively was 85.9%. Lactate clearance was associated in a statistically significant way only with the need for inotropic support on postoperative day 1, p = 0.03. There was a slight trend toward a delay in lactate clearance in those with lower early systolic blood pressures, p = 0.14. Conclusions: Lactate clearance appears to occur largely independently of postoperative blood pressures in the first 16 h after surgery but may be delayed in those requiring inotropic support through the morning or postoperative day one.
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(This article belongs to the Special Issue Cardiothoracic Surgery, 2nd Edition)
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Open AccessSystematic Review
PerClot for Use in Surgical Hemostasis: A Systemic Review and Meta-Analysis of Clinical Data
by
Terri Siebert, Stephen Dierks, Piotr Maniak and Torben Colberg
Surgeries 2025, 6(4), 111; https://doi.org/10.3390/surgeries6040111 - 16 Dec 2025
Abstract
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Objective: To demonstrate that PerClot’s efficacy is non-inferior to other hemostatic treatments and its safety is non-inferior to the standard of care (SoC) during surgery. Methods: Applying keywords and inclusion criteria, we queried electronic databases to conduct a systematic (e.g., Embase and Cochrane
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Objective: To demonstrate that PerClot’s efficacy is non-inferior to other hemostatic treatments and its safety is non-inferior to the standard of care (SoC) during surgery. Methods: Applying keywords and inclusion criteria, we queried electronic databases to conduct a systematic (e.g., Embase and Cochrane Library, etc.) and manual search (e.g., Google Scholar, etc.) for studies from 1 January 2008 (first CE marked date) to 30 March 2024. Results: Five published studies were included in this systematic review. From the included studies, 691 patients received either PerClot (n = 315) or other hemostatic agents/SoC/control (n = 376) in different surgical specialties. All five studies had comparable outcome measures, interventions, and control groups, allowing for the pooling of the study data. The primary outcomes were the achievement of hemostasis and time to hemostasis. At 7 min post-application, PerClot demonstrated non-inferior hemostasis performance as compared to Arista (absolute difference: −1.4%; 95% CI: −7.54, 4.74; p = 0.65). The time to achieve hemostasis was comparable between PerClot and other hemostatic agents (mean difference: 0.00 min; 95% CI: 0.00, 0.00; p = 1.00). No statistically significant difference in adverse event occurrence was observed between PerClot and other hemostatic agents/SoC groups (absolute difference: 0.02; 95% CI: −0.30, 0.35; p = 0.2691) and the absence of new unknown adverse events indicates the safety profile of PerClot. The results of all outcome measures are statistically insignificant. Conclusions: Our systematic review demonstrated that PerClot achieved comparable hemostasis with no new safety concerns and a statistically significant reduction in postoperative drainage volume, indicating its safety, efficacy, and performance as an alternative for hemostasis across multiple surgical specialties.
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Open AccessArticle
New Methodology for the Shoulder Biomechanical CAD Model Position Parametrization
by
Vítor Maranha, Luis Roseiro, Pedro Carvalhais and Maria A. Neto
Surgeries 2025, 6(4), 110; https://doi.org/10.3390/surgeries6040110 - 16 Dec 2025
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Background: The development of CAD, FEA, and biomechanical models of the shoulder is challenging due to the joint’s complexity. The spatial relationships between bones, muscles and ligaments are difficult to parameterize, both statically and dynamically, because these structures move three-dimensionally and synergistically. Methods:
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Background: The development of CAD, FEA, and biomechanical models of the shoulder is challenging due to the joint’s complexity. The spatial relationships between bones, muscles and ligaments are difficult to parameterize, both statically and dynamically, because these structures move three-dimensionally and synergistically. Methods: An assembly of the shoulder joint was developed, including parameterisation of the positional relationships among the rotator cuff structures, with particular focus on the bone components: Humerus, Scapula, Clavicle, and Sternum. Discussion: The abundance of existing CAD models of the shoulder makes it difficult to compare numerical results. Variability in reference frames, positioning assumptions and geometric relationships often hinders reproducibility and cross-study interpretation. Conclusions: The presented methodology supports standardised assembly of a shoulder joint model, ensuring consistent assumptions about the relative positioning of the bony structures. This standardization enables more accurate numerical comparisons across studies and improves the reliability of biomechanical research on the shoulder.
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Open AccessCase Report
Surgical Management of Bilateral Trapeziometacarpal Arthritis: Suspension Arthroplasty and Dual Mobility Prosthesis in the Same Patient, Treated at the Same Time
by
Matteo Guzzini, Alice Patrignani, Claudio Bagni, Rocco De Vitis, Simone Cerciello and Stefano Palermi
Surgeries 2025, 6(4), 109; https://doi.org/10.3390/surgeries6040109 - 6 Dec 2025
Abstract
Background: Trapeziometacarpal osteoarthritis (TMC OA) is a prevalent degenerative disorder that causes considerable pain and functional limitations, especially in older individuals, whose ideal treatment is still debated in the literature. Various treatments are described to restore a good functional outcome of the thumb;
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Background: Trapeziometacarpal osteoarthritis (TMC OA) is a prevalent degenerative disorder that causes considerable pain and functional limitations, especially in older individuals, whose ideal treatment is still debated in the literature. Various treatments are described to restore a good functional outcome of the thumb; over the past 50 years, biological arthroplasties have been considered the gold standard for treating advanced stages of TMC OA. However, in the last decade, the use of dual mobility cup prostheses has significantly increased, with numerous studies reporting excellent clinical outcomes. In this case report, we show the results of a patient treated on the left hand with suspension arthroplasty and on his right hand with dual mobility arthroplasty in one-stage surgery. The aim of this case report is to directly compare outcomes between trapeziometacarpal prosthesis and suspension arthroplasty performed simultaneously in the same patient. Case Presentation: The present case reports a 71-year-old male patient with bilateral TMC osteoarthritis, referred to our clinic in May 2024. His medical history included hypertension, hypertriglyceridemia, paroxysmal atrial fibrillation, and benign prostatic hyperplasia. On examination, the right hand showed grade 3 osteoarthritis according to the Eaton–Littler classification, with the trapezium maintaining adequate bone stock, making the patient eligible for trapeziometacarpal prosthesis implantation. Conversely, the left hand demonstrated scaphotrapezoid arthritis with a slight reduction in trapezial bone stock, indicating the need for trapeziectomy followed by suspension arthroplasty. Both procedures were performed during the same surgical session by the same experienced hand surgeon using a lateral approach. On the right side, the trapeziometacarpal joint surfaces were resected and replaced with a dual mobility prosthesis, while on the left side, the trapezium was excised, and suspension arthroplasty was performed using a slip of the flexor carpi radialis (FCR) tendon. Methods: The patient underwent simultaneous treatment with a dual mobility trapeziometacarpal prosthesis on the right hand and trapeziectomy with suspension arthroplasty on the left hand. Clinical outcomes (grip and pinch strength, pain, QuickDASH, satisfaction, and range of motion) were evaluated at 1, 3, 6, and 12 months. Paired comparative statistics were applied with significance set at p < 0.05. Results: At all follow-up intervals (1, 3, 6, and 12 months), the hand treated with a trapeziometacarpal prosthesis demonstrated superior grip and pinch strength compared to the hand treated with trapeziectomy and suspension arthroplasty, with the greatest difference observed at 3 months. At 12 months, grip strength increased from 28 kg to 40 kg in the prosthesis-treated hand and from 25 kg to 33 kg in the suspension arthroplasty hand. Paired comparisons were performed at each follow-up interval up to 12 months, confirming a significant difference for grip strength. Pain levels (VAS, Visual Analogue Scale) decreased progressively in both hands, with a more rapid reduction in the hand treated with a trapeziometacarpal prosthesis, reaching statistical significance. QuickDASH scores indicated an earlier return to daily activities in the hand treated with the prosthesis, although this difference was not statistically significant. Patient satisfaction was consistently higher for the hand treated with a trapeziometacarpal prosthesis, with the patient reporting a ‘very satisfied’ rating at all timepoints. Range of motion recovery, assessed through the Kapandji score and measurements of thumb abduction and extension, also favored the hand treated with the prosthesis, with statistically significant differences for abduction and extension, whereas the hand treated with trapeziectomy and suspension arthroplasty demonstrated more gradual improvement over time. Conclusions: This case highlights the functional efficacy of both surgical approaches—biological arthroplasty and trapeziometacarpal prosthesis—in the treatment of TMC osteoarthritis. Both procedures resulted in a good clinical outcome and high patient satisfaction. However, recovery was noticeably faster in the hand treated with a trapeziometacarpal prosthesis, which is consistent with findings previously reported in the literature. These observations suggest that, while both techniques are valid and effective, trapeziometacarpal prosthetic replacement may offer a quicker return to function in appropriately selected patients.
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(This article belongs to the Section Hand Surgery and Research)
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