Cells | Top Cited Papers in 2023 in the Section “Cell Signaling”

“Emerging Role of cAMP/AMPK Signaling”
by Muhammad Aslam andYury Ladilov
Cells 2022, 11(2), 308; https://doi.org/10.3390/cells11020308
Available online: https://www.mdpi.com/2073-4409/11/2/308

“Properties and Functions of Fibroblasts and Myofibroblasts in Myocardial Infarction”
by Harikrishnan Venugopal, Anis Hanna, Claudio Humeres and Nikolaos G. Frangogiannis
Cells 2022, 11(9), 1386; https://doi.org/10.3390/cells11091386
Available online: https://www.mdpi.com/2073-4409/11/9/1386

“Insight into the Role of the PI3K/Akt Pathway in Ischemic Injury and Post-Infarct Left Ventricular Remodeling in Normal and Diabetic Heart”
by Bartosz Walkowski, Marcin Kleibert, Miłosz Majka and Małgorzata Wojciechowska
Cells 2022, 11(9), 1553; https://doi.org/10.3390/cells11091553
Available online: https://www.mdpi.com/2073-4409/11/9/1553

“ISG15 and ISGylation in Human Diseases”
by Oygul Mirzalieva, Meredith Juncker, Joshua Schwartzenburg and Shyamal Desai
Cells 2022, 11(3), 538; https://doi.org/10.3390/cells11030538
Available online: https://www.mdpi.com/2073-4409/11/3/538

“cAMP Signaling in Cancer: A PKA-CREB and EPAC-Centric Approach”
by Muhammad Bilal Ahmed, Abdullah A. A. Alghamdi, Salman Ul Islam, Joon-Seok Lee and Young-Sup Lee
Cells 2022, 11(13), 2020; https://doi.org/10.3390/cells11132020
Available online: https://www.mdpi.com/2073-4409/11/13/2020

“New Insights into Hippo/YAP Signaling in Fibrotic Diseases”
by Masum M. Mia and Manvendra K. Singh
Cells 2022, 11(13), 2065; https://doi.org/10.3390/cells11132065
Available online: https://www.mdpi.com/2073-4409/11/13/2065

“Specific NLRP3 Inflammasome Assembling and Regulation in Neutrophils: Relevance in Inflammatory and Infectious Diseases”
by Christophe Paget, Emilie Doz-Deblauwe, Nathalie Winter and Benoit Briard
Cells 2022, 11(7), 1188; https://doi.org/10.3390/cells11071188
Available online: http://www.mdpi.com/2073-4409/11/7/1188

“Early Protective Role of Inflammation in Cardiac Remodeling and Heart Failure: Focus on TNFα and Resident Macrophages”
by Sophie Besse, Sophie Nadaud, Elise Balse and Catherine Pavoine
Cells 2022, 11(7), 1249; https://doi.org/10.3390/cells11071249
Available online: http://www.mdpi.com/2073-4409/11/7/1249

“Calcium Signals during SARS-CoV-2 Infection: Assessing the Potential of Emerging Therapies”
by Sascha Berlansky, Matthias Sallinger, Herwig Grabmayr, Christina Humer, Andreas Bernhard, Marc Fahrner and Irene Frischauf
Cells 2022, 11(2), 253; https://doi.org/10.3390/cells11020253
Available online: http://www.mdpi.com/2073-4409/11/2/253

“Reprogramming of Lipid Metabolism in Lung Cancer: An Overview with Focus on EGFR-Mutated Non-Small Cell Lung Cancer”
by Kamal Eltayeb, Silvia La Monica, Marcello Tiseo, Roberta Alfieri and Claudia Fumarola
Cells 2022, 11(3), 413; https://doi.org/10.3390/cells11030413
Available online: http://www.mdpi.com/2073-4409/11/3/413

“KRAS as a Modulator of the Inflammatory Tumor Microenvironment: Therapeutic Implications”
by Flávia Pereira, Anabela Ferreira, Celso Albuquerque Reis, Maria João Sousa, Maria José Oliveira and Ana Preto
Cells 2022, 11(3), 398; https://doi.org/10.3390/cells11030398
Available online: http://www.mdpi.com/2073-4409/11/3/398

“Comparative Efficacy and Safety of Tezepelumab and Other Biologics in Patients with Inadequately Controlled Asthma According to Thresholds of Type 2 Inflammatory Biomarkers: A Systematic Review and Network Meta-Analysis”
by Koichi Ando, Yosuke Fukuda, Akihiko Tanaka and Hironori Sagara
Cells 2022, 11(5), 819; https://doi.org/10.3390/cells11050819
Available online: http://www.mdpi.com/2073-4409/11/5/819

“BMP Signaling Pathway in Dentin Development and Diseases”
by Mengmeng Liu, Graham Goldman, Mary MacDougall and Shuo Chen
Cells 2022, 11(14), 2216; https://doi.org/10.3390/cells11142216
Available online: http://www.mdpi.com/2073-4409/11/14/2216

“Bioenergetic Aspects of Mitochondrial Actions of Thyroid Hormones”
by Federica Cioffi, Antonia Giacco, Fernando Goglia and Elena Silvestri
Cells 2022, 11(6), 997; https://doi.org/10.3390/cells11060997
Available online: http://www.mdpi.com/2073-4409/11/6/997

“Cannabinoids Alleviate the LPS-Induced Cytokine Storm via Attenuating NLRP3 Inflammasome Signaling and TYK2-Mediated STAT3 Signaling Pathways In Vitro”
by Santosh V. Suryavanshi, Mariia Zaiachuk, Nazar Pryimak, Igor Kovalchuk and Olga Kovalchuk
Cells 2022, 11(9), 1391; https://doi.org/10.3390/cells11091391
Available online: http://www.mdpi.com/2073-4409/11/9/1391

“Interleukin-1 and Nuclear Factor Kappa B Signaling Promote Breast Cancer Progression and Treatment Resistance”
by Sydney Diep, Mahita Maddukuri, Stephanie Yamauchi, Ganamee Geshow and Nikki A. Delk
Cells 2022, 11(10), 1673; https://doi.org/10.3390/cells11101673
Available online: http://www.mdpi.com/2073-4409/11/10/1673

“Therapeutic Targeting of NF-κB in Acute Lung Injury: A Double-Edged Sword”
by Michelle Warren Millar, Fabeha Fazal and Arshad Rahman
Cells 2022, 11(20), 3317; https://doi.org/10.3390/cells11203317
Available online: http://www.mdpi.com/2073-4409/11/20/3317

“Genomic Hippo Pathway Alterations and Persistent YAP/TAZ Activation: New Hallmarks in Head and Neck Cancer”
by Farhoud Faraji, Sydney I. Ramirez, Paola Y. Anguiano Quiroz, Amaya N. Mendez-Molina and J. Silvio Gutkind
Cells 2022, 11(8), 1370; https://doi.org/10.3390/cells11081370
Available online: http://www.mdpi.com/2073-4409/11/8/1370

“Single-Cell RNA-Sequencing: Astrocyte and Microglial Heterogeneity in Health and Disease”
by Michael S. Spurgat and Shao-Jun Tang
Cells 2022, 11(13), 2021; https://doi.org/10.3390/cells11132021
Available online: http://www.mdpi.com/2073-4409/11/13/2021

“Vitamin D Receptor Influences Intestinal Barriers in Health and Disease”
by Jun Sun and Yong-Guo Zhang
Cells 2022, 11(7), 1129; https://doi.org/10.3390/cells11071129
Available online: http://www.mdpi.com/2073-4409/11/7/1129

“C-C Chemokine Receptor 7 in Cancer”
by Colin A. Bill, Christopher M. Allen and Charlotte M. Vines
Cells 2022, 11(4), 656; https://doi.org/10.3390/cells11040656
Available online: http://www.mdpi.com/2073-4409/11/4/656

“Ibrutinib in the Treatment of Solid Tumors: Current State of Knowledge and Future Directions”
by Katarzyna Szklener, Adam Michalski, Klaudia Żak, Michał Piwoński and Sławomir Mańdziuk
Cells 2022, 11(8), 1338; https://doi.org/10.3390/cells11081338
Available online: http://www.mdpi.com/2073-4409/11/8/1338

“Crucial Role of Oncogenic KRAS Mutations in Apoptosis and Autophagy Regulation: Therapeutic Implications”
by Anabela Ferreira, Flávia Pereira, Celso Reis, Maria José Oliveira, Maria João Sousa and Ana Preto
Cells 2022, 11(14), 2183; https://doi.org/10.3390/cells11142183
Available online: http://www.mdpi.com/2073-4409/11/14/2183

“Identification, Quantification, and Characterization of HIV-1 Reservoirs in the Human Brain”
by Maribel Donoso, Daniela D’Amico, Silvana Valdebenito, Cristian A. Hernandez, Brendan Prideaux and Eliseo A. Eugenin
Cells 2022, 11(15), 2379; https://doi.org/10.3390/cells11152379
Available online: http://www.mdpi.com/2073-4409/11/15/2379

“NLRP6 Inflammasome Modulates Disease Progression in a Chronic-Plus-Binge Mouse Model of Alcoholic Liver Disease”
by Rebecca Elena Mainz, Stefanie Albers, Madhuri Haque, Roland Sonntag, Nicole Simone Treichel, Thomas Clave, Eicke Latz, Kai Markus Schneider, Christian Trautwein and Tobias Otto
Cells 2022, 11(2), 182; https://doi.org/10.3390/cells11020182
Available online: http://www.mdpi.com/2073-4409/11/2/182

“Hypoxia-Inducible Factor Signaling in Inflammatory Lung Injury and Repair”
by Colin E. Evans
Cells 2022, 11(2), 183; https://doi.org/10.3390/cells11020183
Available online: http://www.mdpi.com/2073-4409/11/2/183

“Intestinal Epithelial AMPK Deficiency Causes Delayed Colonic Epithelial Repair in DSS-Induced Colitis”
by Séverine Olivier, Hanna Diounou, Camille Pochard, Lisa Frechin, Emilie Durieu, Marc Foretz, Michel Neunlist, Malvyne Rolli-Derkinderen and Benoit Viollet
Cells 2022, 11(4), 590; https://doi.org/10.3390/cells11040590
Available online: http://www.mdpi.com/2073-4409/11/4/590

“Dissecting miRNA–Gene Networks to Map Clinical Utility Roads of Pharmacogenomics-Guided Therapeutic Decisions in Cardiovascular Precision Medicine”
by Fani Chatzopoulou, Konstantinos A. Kyritsis, Christos I. Papagiannopoulos, Eleftheria Galatou, Nikolaos Mittas, Nikoleta F. Theodoroula, Andreas S. Papazoglou, Efstratios Karagiannidis, Maria Chatzidimitriou, Anna Papa et al.
Cells 2022, 11(4), 607; https://doi.org/10.3390/cells11040607
Available online: http://www.mdpi.com/2073-4409/11/4/607

“Microbial Metabolite Regulation of Epithelial Cell-Cell Interactions and Barrier Function”
by Alfredo Ornelas, Alexander S. Dowdell, J. Scott Lee and Sean P. Colgan
Cells 2022, 11(6), 944; https://doi.org/10.3390/cells11060944
Available online: http://www.mdpi.com/2073-4409/11/6/944

“Why Do Marijuana and Synthetic Cannabimimetics Induce Acute Myocardial Infarction in Healthy Young People?”
by Jolanta Weresa, Anna Pędzińska-Betiuk, Krzysztof Mińczuk, Barbara Malinowska and Eberhard Schlicker
Cells 2022, 11(7), 1142; https://doi.org/10.3390/cells11071142
Available online: http://www.mdpi.com/2073-4409/11/7/1142

“Selectin-Mediated Signaling—Shedding Light on the Regulation of Integrin Activity in Neutrophils”
by Anika Cappenberg, Marina Kardell and Alexander Zarbock
Cells 2022, 11(8), 1310; https://doi.org/10.3390/cells11081310
Available online: http://www.mdpi.com/2073-4409/11/8/1310

“Lethal and Non-Lethal Functions of Caspases in the DNA Damage Response”
by Karla E. Lopez and Lisa Bouchier-Hayes
Cells 2022, 11(12), 1887; https://doi.org/10.3390/cells11121887
Available online: http://www.mdpi.com/2073-4409/11/12/1887

“The Roles of TNFR2 Signaling in Cancer Cells and the Tumor Microenvironment and the Potency of TNFR2 Targeted Therapy”
by Hiroyuki Takahashi, Gumpei Yoshimatsu and Denise Louise Faustman
Cells 2022, 11(12), 1952; https://doi.org/10.3390/cells11121952
Available online: http://www.mdpi.com/2073-4409/11/12/1952

“Dysregulated Ca₂₊ Homeostasis as a Central Theme in Neurodegeneration: Lessons from Alzheimer’s Disease and Wolfram Syndrome”
by Manon Callens, Jens Loncke and Geert Bultynck
Cells 2022, 11(12), 1963; https://doi.org/10.3390/cells11121963
Available online: http://www.mdpi.com/2073-4409/11/12/1963

“Signaling by LncRNAs: Structure, Cellular Homeostasis, and Disease Pathology”
by Revathy Nadhan, Ciro Isidoro, Yong Sang Song and Danny N. Dhanasekaran
Cells 2022, 11(16), 2517; https://doi.org/10.3390/cells11162517
Available online: http://www.mdpi.com/2073-4409/11/16/2517

“KRAS G12D Mutation Subtype in Pancreatic Ductal Adenocarcinoma: Does It Influence Prognosis or Stage of Disease at Presentation?”
by Henry Shen, Joanne Lundy, Andrew H. Strickland, Marion Harris, Michael Swan, Christopher Desmond, Brendan J. Jenkins and Daniel Croagh
Cells 2022, 11(19), 3175; https://doi.org/10.3390/cells11193175
Available online: http://www.mdpi.com/2073-4409/11/19/3175

“HMGB1-Mediated Activation of the Inflammatory-Reparative Response Following Myocardial Infarction”
by Eleonora Foglio, Laura Pellegrini, Matteo Antonio Russo and Federica Limana
Cells 2022, 11(2), 216; https://doi.org/10.3390/cells11020216
Available online: http://www.mdpi.com/2073-4409/11/2/216

“Nuclear Receptor PXR in Drug-Induced Hypercholesterolemia”
by Mikko Karpale, Janne Hukkanen and Jukka Hakkola
Cells 2022, 11(3), 313; https://doi.org/10.3390/cells11030313
Available online: http://www.mdpi.com/2073-4409/11/3/313

“Deubiquitinases in Neurodegeneration”
by Abudu I. Bello, Rituparna Goswami, Shelby L. Brown, Kara Costanzo, Taylor Shores, Shefaa Allan, Revan Odah and Ryan D. Mohan
Cells 2022, 11(3), 556; https://doi.org/10.3390/cells11030556
Available online: http://www.mdpi.com/2073-4409/11/3/556

“Maintenance of NAD+ Homeostasis in Skeletal Muscle during Aging and Exercise”
by Li Li Ji and Dongwook Yeo
Cells 2022, 11(4), 710; https://doi.org/10.3390/cells11040710
Available online: http://www.mdpi.com/2073-4409/11/4/710

“Normal and Neoplastic Growth Suppression by the Extended Myc Network”
by Edward V. Prochownik and Huabo Wang
Cells 2022, 11(4), 747; https://doi.org/10.3390/cells11040747
Available online: http://www.mdpi.com/2073-4409/11/4/747

“To Detach, Migrate, Adhere, and Metastasize: CD97/ADGRE5 in Cancer”
by Gabriela Aust, Leyu Zheng and Marianne Quaas
Cells 2022, 11(9), 1538; https://doi.org/10.3390/cells11091538
Available online: http://www.mdpi.com/2073-4409/11/9/1538

“Global PIEZO1 Gain-of-Function Mutation Causes Cardiac Hypertrophy and Fibrosis in Mice”
by Fiona Bartoli, Elizabeth L. Evans, Nicola M. Blythe, Leander Stewart, Eulashini Chuntharpursat-Bon, Marjolaine Debant, Katie E. Musialowski, Laeticia Lichtenstein, Gregory Parsonage, T. Simon Futers et al.
Cells 2022, 11(7), 1199; https://doi.org/10.3390/cells11071199
Available online: http://www.mdpi.com/2073-4409/11/7/1199

“Distinct CholinomiR Blood Cell Signature as a Potential Modulator of the Cholinergic System in Women with Fibromyalgia Syndrome”
by Christoph Erbacher, Shani Vaknine, Gilli Moshitzky, Sebastian Lobentanzer, Lina Eisenberg, Dimitar Evdokimov, Claudia Sommer, David S. Greenberg, Hermona Soreq and Nurcan Üçeyler
Cells 2022, 11(8), 1276; https://doi.org/10.3390/cells11081276
Available online: http://www.mdpi.com/2073-4409/11/8/1276

“How Pyroptosis Contributes to Inflammation and Fibroblast-Macrophage Cross-Talk in Rheumatoid Arthritis”
by Benjamin Demarco, Sara Danielli, Fabian A. Fischer and Jelena S. Bezbradica
Cells 2022, 11(8), 1307; https://doi.org/10.3390/cells11081307
Available online: http://www.mdpi.com/2073-4409/11/8/1307

“p66Shc in Cardiovascular Pathology”
by Landon Haslem, Jennifer M. Hays and Franklin A. Hays
Cells 2022, 11(11), 1855; https://doi.org/10.3390/cells11111855
Available online: http://www.mdpi.com/2073-4409/11/11/1855

“Involvement of Nuclear Factor-κB in Inflammation and Neuronal Plasticity Associated with Post-Traumatic Stress Disorder”
by Sudhiranjan Gupta and Rakeshwar S. Guleria
Cells 2022, 11(13), 2034; https://doi.org/10.3390/cells11132034
Available online: http://www.mdpi.com/2073-4409/11/13/2034