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Reports, Volume 6, Issue 3

2023 September - 14 articles

Cover Story: For the past 60 years, the dopamine hypothesis of schizophrenia has been the operating system of Western psychiatry. It is now time to step back and evaluate the results. Despite decades of treatment with postsynaptic dopamine blockers, schizophrenia outcome studies reveal less than 15% sustained recovery for patients, with long-term public psychiatric facilities, such as State hospitals, continuing to exist. What if excessive dopamine transmission in the brain is not the cause of schizophrenia? What if gut microbes translocate into the host circulation and the immune system response damages brain cells? The microbial translocation hypothesis opens new intervention avenues, including Aryl Hydrocarbon antagonists, recombinant IL-22, and vagal stimulation. View this paper
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Articles (14)

  • Case Report
  • Open Access
1 Citations
3,082 Views
8 Pages

Implementation of an Electrosurgical Checklist in a Podiatry Unit in Relation to a Case of Inadvertent Burns during Hallux Valgus Surgery

  • Antonio Córdoba-Fernández,
  • María Dolores Jiménez-Cristino,
  • Francisco Javier Mármol-García and
  • Victoria Eugenia Córdoba-Jiménez

14 September 2023

Iatrogenic burns are unpleasant and sometimes difficult to explain to patients. Podiatric surgeons routinely use electrosurgical devices to cut and coagulate tissue during surgical procedures. Although advances in technology have made electrosurgery...

  • Case Report
  • Open Access
1 Citations
4,932 Views
10 Pages

Paroxysmal Nocturnal Hemoglobinuria: A Case Report in a Pandemic Environment

  • Vanda Peixoto,
  • Ana Carneiro,
  • Fernanda Trigo,
  • Mónica Vieira and
  • Cristina Prudêncio

8 September 2023

Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal, rare, complement-mediated hemolytic anemia. PNH can be associated with marrow failure and thrombophilia. We present a clinical report of splenic vein thrombosis in a patient with classic PNH. A 4...

  • Article
  • Open Access
2,375 Views
16 Pages

Transvenous Lead Extraction in a European Low-Volume Center without On-Site Surgical Support

  • Mohamed Dardari,
  • Corneliu Iorgulescu,
  • Vlad Bataila,
  • Alexandru Deaconu,
  • Eliza Cinteza,
  • Radu Vatasescu,
  • Paul Padovani,
  • Corina Maria Vasile and
  • Maria Dorobantu

7 September 2023

Indications for cardiac implantable electronic devices (CIEDs) are increasing. Almost one-third of device-related infections are endocarditis. Transvenous lead extraction (TLE) has emerged as an effective and safe approach for treating device-related...

  • Case Report
  • Open Access
1 Citations
3,855 Views
10 Pages

Challenges in the Diagnosis of Parathyroid Cancer: Unraveling the Diagnostic Maze

  • Mihaela Stanciu,
  • Remus Calin Cipaian,
  • Ruxandra Ristea,
  • Corina Maria Vasile,
  • Mihaela Popescu and
  • Florina Ligia Popa

24 August 2023

Parathyroid carcinoma (PC) is a rare and aggressive cancer affecting the parathyroid glands, presenting diagnostic and therapeutic challenges due to its rarity and overlapping features with benign parathyroid disease. This report describes the case o...

  • Case Report
  • Open Access
1 Citations
2,167 Views
11 Pages

Challenges of a Patient with Thromboembolism

  • Andra Oancea,
  • Alexandra Maștaleru,
  • Irina Mihaela Abdulan,
  • Alexandru Dan Costache,
  • Mădălina Ioana Zota,
  • Robert Negru,
  • Ștefana Moisă,
  • Laura Mihaela Trandafir and
  • Maria Magdalena Leon

22 August 2023

Background: FV Leiden is an autosomal dominant disease, representing one of the most prevalent genetic causes for hereditary thrombophilia manifested by venous thromboembolism. Methods: We report a case of a 30-year-old patient who was admitted for e...

  • Case Report
  • Open Access
3,340 Views
6 Pages

Spasm of Near Reflex in a Patient with Autism Spectrum Disorder: A Case Report

  • Satoshi Ueki,
  • Yukari Hasegawa,
  • Tetsuhisa Hatase,
  • Takako Hanyu,
  • Jun Egawa,
  • Atsushi Miki and
  • Takeo Fukuchi

8 August 2023

Spasm of near reflex (SNR) involves intermittent spasm of one or more of the three near reflex components. Psychiatric disorders are one cause of SNR. We describe a patient with SNR diagnosed with autism spectrum disorder (ASD). A 36-year-old male wi...

  • Case Report
  • Open Access
2,431 Views
8 Pages

Black Esophagus and Recurrence of Duodenal Ulcers: Two Signs of the Same Pathogenic Pathway? A Case Report

  • Daniele Balducci,
  • Claudia Quatraccioni,
  • Luigi Maria Daretti,
  • Michele Montori,
  • Emanuele Bendia,
  • Luca Maroni and
  • Antonio Benedetti

7 August 2023

Black esophagus or acute esophageal necrosis is characterized by circumferential black discoloration of the distal esophageal mucosa. It is a rare condition with a multifactorial pathogenesis, and its most common clinical presentation is acute upper...

  • Review
  • Open Access
6 Citations
5,636 Views
27 Pages

1 August 2023

In 1957, Arvid Carlsson discovered that dopamine, at the time believed to be nothing more than a norepinephrine precursor, was a brain neurotransmitter in and of itself. By 1963, postsynaptic dopamine blockade had become the cornerstone of psychiatri...

  • Case Report
  • Open Access
2,605 Views
7 Pages

Efficacy of Corticosteroids and Intravenous Immunoglobulins in a Patient with Toxic Epidermal Necrolysis Secondary to Sulfadoxine: A Case Report and Literature Review

  • Alba Escolà-Rodríguez,
  • Ángel Marcos-Fendian,
  • Carla Bastida,
  • Javier Gil Lianes,
  • Pedro Castro,
  • José Manuel Mascaró and
  • Dolors Soy Muner

31 July 2023

Toxic epidermal necrolysis (TEN) is a rare life-threatening mucocutaneous reaction characterized by epidermal detachment. Treatment success relies on early diagnosis, rapid withdrawal of the causative drug and supportive care. However, clinical evide...

  • Case Report
  • Open Access
3 Citations
2,838 Views
7 Pages

Heterologous Platelet-Rich Plasma in the Treatment of Severe Skin Damage

  • Cristina Vocca,
  • Francesco Romano,
  • Gianmarco Marcianò,
  • Vincenzo Cianconi,
  • Davida Mirra,
  • Andrea Dominijanni,
  • Giovambattista De Sarro and
  • Luca Gallelli

21 July 2023

Accidental soft tissue injuries are a frequent injury. Platelet-rich plasma (PRP) is an interesting therapeutic option for wounds and skin damage. In this case report, we describe a 37-year-old man that presented to our ward of pain medicine for an a...

  • Case Report
  • Open Access
2,260 Views
9 Pages

A Multiple Synergic Treatment for Non-Healing Ulcer Management in a Patient with Klippel–Trenaunay Syndrome

  • Cristina Vocca,
  • Gianmarco Marcianò,
  • Vincenzo Rania,
  • Luca Catarisano,
  • Caterina Palleria,
  • Salvatore Ciranni,
  • Giuseppina Torcia,
  • Raffaele Serra,
  • Francesco Monea and
  • Luca Gallelli
  • + 3 authors

20 July 2023

Klippel–Trenanauy syndrome (KTS) is a rare genetic disease determined by overexpression of the phosphatidylinositol-4-5-bisphosphate 3 kinase catalytic subunit (PIK3CA) gene. The clinical presentation is characterized by venous and capillary ma...

  • Case Report
  • Open Access
3,065 Views
7 Pages

18 July 2023

Obstructive sleep apnea (OSA) is well known to often improve with non-supine positioning as opposed to supine positioning. Emerging research supports a role for sleep position management in patients with central sleep apnea (CSA) as well. We report a...

  • Article
  • Open Access
3,245 Views
10 Pages

Background: Poor clinical outcomes in patients with severe COVID-19 occur due to many factors that require elucidation. The objective of this study was to describe the outcomes of critically ill patients with COVID-19 and identify the risk factors fo...

  • Case Report
  • Open Access
3,827 Views
10 Pages

17q21.31 Microduplication Syndrome in a Patient with Autism Spectrum Disorder, Macrocephaly, and Intellectual Disability

  • Federica Saia,
  • Adriana Prato,
  • Caterina Angela Florio,
  • Vincenzo Paolo Cutrone and
  • Renata Rizzo

The chromosome 17q21.31 microduplication syndrome is a rare genetic syndrome presenting with craniofacial dysmorphisms, psychomotor delay, microcephaly, behavioral disorders, and poor social interaction. Only ten patients have been reported in the li...

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Reports - ISSN 2571-841X