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Neuroglia, Volume 6, Issue 1

March 2025 - 14 articles

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Articles (14)

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Review

12 Citations

10,194 Views

45 Pages

Glial Perturbation in Metal Neurotoxicity: Implications for Brain Disorders

Olayemi K. Ijomone,
Ileje I. Ukwubile,
Vivian O. Aneke,
Tobiloba S. Olajide,
Happiness O. Inyang,
Omolabake I. Omotosho,
Toheeb O. Oyerinde,
Victor E. Anadu,
Tolulope J. Gbayisomore and
Oritoke M. Okeowo
+ 3 authors

Neuroglia2025, 6(1), 4;https://doi.org/10.3390/neuroglia6010004

6 January 2025

Overexposure of humans to heavy metals and essential metals poses a significant risk for the development of neurological and neurodevelopmental disorders. The mechanisms through which these metals exert their effects include the generation of reactiv...

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Review

1 Citations

4,075 Views

22 Pages

Sex and Region-Specific Differences in Microglial Morphology and Function Across Development

Indra R. Bishnoi and
Evan A. Bordt

Neuroglia2025, 6(1), 2;https://doi.org/10.3390/neuroglia6010002

4 January 2025

Microglia are exceptionally dynamic resident innate immune cells within the central nervous system, existing on a continuum of morphologies and functions throughout their lifespan. They play vital roles in response to injuries and infections, clearin...

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Article

2 Citations

2,147 Views

14 Pages

Brain-Homing Peptide Expression on the Membrane Enhances the Delivery of Exosomes to Neural Cells and Tissue

Jonhoi Smith,
Melvin Field and
Kiminobu Sugaya

Neuroglia2025, 6(1), 3;https://doi.org/10.3390/neuroglia6010003

4 January 2025

Background/Objectives: Glioblastoma (GBM), a highly aggressive grade IV astrocytoma, poses a major therapeutic challenge due to the resistance of cancer stem cells (CSCs) existing within its cell population to the conventional therapies. Recently, we...

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Review

3,268 Views

17 Pages

BMAL1 in Astrocytes: A Protective Role in Alzheimer’s and Parkinson’s Disease

David Brash-Arias,
Luis I. García,
Gonzalo Aranda-Abreu,
Rebeca Toledo-Cárdenas,
César Pérez-Estudillo and
Donaji Chi-Castañeda

Neuroglia2025, 6(1), 1;https://doi.org/10.3390/neuroglia6010001

2 January 2025

Astrocyte activation is a critical aspect of brain health and disease, and the central circadian clock protein BMAL1 has emerged as a regulator of astrogliosis and inflammatory gene expression. Bmal1 deletion in astrocytes reprograms endolysosomal tr...

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Neuroglia - ISSN 2571-6980

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