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Health Impact and Therapeutic Manipulation of the Gut Microbiome

Department of Food Science and Biotechnology, Kangwon National University, Chuncheon 200-701, Korea
Department of Microbiology/Immunology, McGill University, Montreal, QC H3A 2B4, Canada
SportBiomics, Sacramento Inc., Sacramento, CA 95660, USA
Author to whom correspondence should be addressed.
High-Throughput 2020, 9(3), 17;
Received: 24 March 2020 / Revised: 15 July 2020 / Accepted: 19 July 2020 / Published: 29 July 2020
(This article belongs to the Special Issue Human Microbiome and Diseases: Implications for Novel Therapies)
Recent advances in microbiome studies have revealed much information about how the gut virome, mycobiome, and gut bacteria influence health and disease. Over the years, many studies have reported associations between the gut microflora under different pathological conditions. However, information about the role of gut metabolites and the mechanisms by which the gut microbiota affect health and disease does not provide enough evidence. Recent advances in next-generation sequencing and metabolomics coupled with large, randomized clinical trials are helping scientists to understand whether gut dysbiosis precedes pathology or gut dysbiosis is secondary to pathology. In this review, we discuss our current knowledge on the impact of gut bacteria, virome, and mycobiome interactions with the host and how they could be manipulated to promote health. View Full-Text
Keywords: microbiome; biomarkers; personalized nutrition; microbes; metagenomics microbiome; biomarkers; personalized nutrition; microbes; metagenomics
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MDPI and ACS Style

Daliri, E.B.-M.; Ofosu, F.K.; Chelliah, R.; Lee, B.H.; Oh, D.-H. Health Impact and Therapeutic Manipulation of the Gut Microbiome. High-Throughput 2020, 9, 17.

AMA Style

Daliri EB-M, Ofosu FK, Chelliah R, Lee BH, Oh D-H. Health Impact and Therapeutic Manipulation of the Gut Microbiome. High-Throughput. 2020; 9(3):17.

Chicago/Turabian Style

Daliri, Eric B.-M., Fred K. Ofosu, Ramachandran Chelliah, Byong H. Lee, and Deog-Hwan Oh. 2020. "Health Impact and Therapeutic Manipulation of the Gut Microbiome" High-Throughput 9, no. 3: 17.

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