Next Article in Journal
Antimicrobial Resistance in E. coli Isolated from Chicken Cecum Samples and Factors Contributing to Antimicrobial Resistance in Nepal
Next Article in Special Issue
Infectious Disease Modeling with Socio-Viral Behavioral Aspects—Lessons Learned from the Spread of SARS-CoV-2 in a University
Previous Article in Journal
Impact of COVID-19 on Tuberculosis Indicators in Brazil: A Time Series and Spatial Analysis Study
Previous Article in Special Issue
Mortality in Four Waves of COVID-19 Is Differently Associated with Healthcare Capacities Affected by Economic Disparities
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
TropicalMed
Volume 7
Issue 9
10.3390/tropicalmed7090248
tropicalmed-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
Article

A Risk Prediction Model and Risk Score of SARS-CoV-2 Infection Following Healthcare-Related Exposure

by
Kantarida Sripanidkulchai
1,
Pinyo Rattanaumpawan
2,
Winai Ratanasuwan
1,
Nasikarn Angkasekwinai
2,
Susan Assanasen
2,
Peerawong Werarak
1,
Oranich Navanukroh
1,
Phatharajit Phatharodom
1 and
Teerapong Tocharoenchok
3,*
1
Department of Preventive and Social Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
2
Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
3
Division of Cardiothoracic Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
*
Author to whom correspondence should be addressed.
Trop. Med. Infect. Dis. 2022, 7(9), 248; https://doi.org/10.3390/tropicalmed7090248
Submission received: 27 August 2022 / Revised: 10 September 2022 / Accepted: 10 September 2022 / Published: 14 September 2022
(This article belongs to the Special Issue COVID-19: Current Status and Future Prospects)
Browse Figures
Review Reports Versions Notes

Abstract

Hospital workers are at high risk of contact with COVID-19 patients. Currently, there is no evidence-based, comprehensive risk assessment tool for healthcare-related exposure; so, we aimed to identify independent factors related to COVID-19 infection in hospital workers following workplace exposure(s) and construct a risk prediction model. We analyzed the COVID-19 contact tracing dataset from 15 July to 31 December 2021 using multiple logistic regression analysis, considering exposure details, demographics, and vaccination history. Of 7146 included exposures to confirmed COVID-19 patients, 229 (4.2%) had subsequently tested positive via RT-PCR. Independent risk factors for a positive test were having symptoms (adjusted odds ratio 4.94, 95%CI 3.83–6.39), participating in an unprotected aerosol-generating procedure (aOR 2.87, 1.66–4.96), duration of exposure >15 min (aOR 2.52, 1.82–3.49), personnel who did not wear a mask (aOR 2.49, 1.75–3.54), exposure to aerodigestive secretion (aOR 1.5, 1.03–2.17), index patient not wearing a mask (aOR 1.44, 1.01–2.07), and exposure distance <1 m without eye protection (aOR 1.39, 1.02–1.89). High-potency vaccines and high levels of education protected against infection. A risk model and scoring system with good discrimination power were built. Having symptoms, unprotected exposure, lower education level, and receiving low potency vaccines increased the risk of laboratory-confirmed COVID-19 following healthcare-related exposure events.
Keywords: COVID-19; SARS-CoV-2; occupational exposure; risk factors; personal protective equipment COVID-19; SARS-CoV-2; occupational exposure; risk factors; personal protective equipment

Share and Cite

MDPI and ACS Style

Sripanidkulchai, K.; Rattanaumpawan, P.; Ratanasuwan, W.; Angkasekwinai, N.; Assanasen, S.; Werarak, P.; Navanukroh, O.; Phatharodom, P.; Tocharoenchok, T. A Risk Prediction Model and Risk Score of SARS-CoV-2 Infection Following Healthcare-Related Exposure. Trop. Med. Infect. Dis. 2022, 7, 248. https://doi.org/10.3390/tropicalmed7090248

AMA Style

Sripanidkulchai K, Rattanaumpawan P, Ratanasuwan W, Angkasekwinai N, Assanasen S, Werarak P, Navanukroh O, Phatharodom P, Tocharoenchok T. A Risk Prediction Model and Risk Score of SARS-CoV-2 Infection Following Healthcare-Related Exposure. Tropical Medicine and Infectious Disease. 2022; 7(9):248. https://doi.org/10.3390/tropicalmed7090248

Chicago/Turabian Style

Sripanidkulchai, Kantarida, Pinyo Rattanaumpawan, Winai Ratanasuwan, Nasikarn Angkasekwinai, Susan Assanasen, Peerawong Werarak, Oranich Navanukroh, Phatharajit Phatharodom, and Teerapong Tocharoenchok. 2022. "A Risk Prediction Model and Risk Score of SARS-CoV-2 Infection Following Healthcare-Related Exposure" Tropical Medicine and Infectious Disease 7, no. 9: 248. https://doi.org/10.3390/tropicalmed7090248

APA Style

Sripanidkulchai, K., Rattanaumpawan, P., Ratanasuwan, W., Angkasekwinai, N., Assanasen, S., Werarak, P., Navanukroh, O., Phatharodom, P., & Tocharoenchok, T. (2022). A Risk Prediction Model and Risk Score of SARS-CoV-2 Infection Following Healthcare-Related Exposure. Tropical Medicine and Infectious Disease, 7(9), 248. https://doi.org/10.3390/tropicalmed7090248

Article Metrics

Back to TopTop