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Allergies, Volume 5, Issue 1

2025 March - 8 articles

Cover Story: Peanut allergy diagnosis is evolving, with advanced technologies that improve specificity and sensitivity while reducing patient risk. Traditional diagnostic methods such as skin prick tests and serum IgE testing have limitations, including false positives and variability. Emerging techniques, including component-resolved diagnostics, basophil activation tests, molecular allergy diagnostics, and artificial intelligence, offer a more precise, personalized approach. These innovations provide better risk stratification, guide treatment decisions, and may replace time-intensive oral food challenges. As peanut allergy prevalence rises, improved diagnostics will be crucial for patient safety and quality of life. View this paper
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Articles (8)

  • Article
  • Open Access
2 Citations
2,775 Views
11 Pages
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Purification and Epitope Mapping of Jug r 4, a Major Walnut Allergen

  • Stephen A. Y. Gipson,
  • Jacqueline B. Nesbit,
  • Lauren T. Swientoniewski,
  • Stephen I. Rogers,
  • S. Shahzad Mustafa,
  • Stephen C. Dreskin,
  • Suzanne S. Teuber,
  • Hsiaopo Cheng and
  • Soheila J. Maleki
Allergies2025, 5(1), 8;https://doi.org/10.3390/allergies5010008

13 March 2025

Background: Tree nut allergy affects approximately 1% of the U.S. population and the prevalence is increasing. Walnut allergy is the most commonly reported tree nut allergy in the United States. This study aimed to investigate the IgE cross-reactivit...

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  • Article
  • Open Access
2,442 Views
11 Pages
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A Survey on Seasonal Symptoms in Subjects with and Without Allergic Rhinitis Diagnosis

  • Arthur Helbling,
  • Mathilde Foglierini,
  • Victor Colin,
  • Yannick D. Muller,
  • Elisabeth Schuller,
  • Annika Stern and
  • Kaspar Strub
Allergies2025, 5(1), 7;https://doi.org/10.3390/allergies5010007

5 March 2025

In Switzerland, only scarce data are available on the prevalence and treatment of allergic rhinitis. Although the presence of AR symptoms in temporal relation to the respective aeroallergen is indicative, still a substantial number of affected indivi...

Full Article
  • Review
  • Open Access
1 Citations
7,010 Views
13 Pages
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Emerging Treatment Options for Peanut Allergy

  • Travis Satnarine,
  • Alana Xavier de Almeida,
  • Malaika Woody,
  • Krisia Banegas Carballo,
  • Diana Chan,
  • Pytregay Thompson,
  • Gary Kleiner and
  • Melissa Gans
Allergies2025, 5(1), 5;https://doi.org/10.3390/allergies5010005

19 February 2025

Peanut allergy, a significant public health issue, poses challenges due to its potential for life-threatening anaphylaxis and profound impact on quality of life. Traditional management approaches, including allergen avoidance and epinephrine administ...

Full Article
  • Review
  • Open Access
3 Citations
6,470 Views
16 Pages
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Peanut Allergy Diagnosis: Current Practices, Emerging Technologies, and Future Directions

  • Travis Satnarine,
  • Nadia Makkoukdji,
  • Valishti Pundit,
  • Alexia Vignau,
  • Pranav Sharma,
  • Duenna Warren,
  • Gary Kleiner and
  • Melissa Gans
Allergies2025, 5(1), 4;https://doi.org/10.3390/allergies5010004

13 February 2025

Peanut allergy presents a significant and growing public health concern, marked by its increasing prevalence and potential for severe allergic reactions. Traditional diagnostic methods, such as skin prick testing and serum IgE assays, serve as corner...

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  • Article
  • Open Access
2 Citations
3,408 Views
16 Pages
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Real-World Outcomes and Healthcare Utilization of Lanadelumab in Spain: Insights from First Cohort of Difficult-to-Treat Hereditary Angioedema Cases

  • Inmaculada Sánchez-Machín,
  • Ruperto González-Pérez,
  • Elena Mederos-Luis,
  • Sara García-Gil and
  • Paloma Poza-Guedes
Allergies2025, 5(1), 3;https://doi.org/10.3390/allergies5010003

11 February 2025

Background/Objectives: Hereditary angioedema (HAE) is a rare genetic condition marked by recurring episodes of intense swelling that affect the skin, gastrointestinal system, and airways. Lanadelumab, a monoclonal antibody that inhibits plasma kallik...

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  • Article
  • Open Access
2,416 Views
16 Pages
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Clinical and Immunological Features in Limpet (Patella sp.) Allergy in Subtropical Areas: A New Trigger for Food Anaphylaxis

  • Elena Mederos-Luis,
  • Tania Galán,
  • María J. Martínez,
  • Ruperto González-Pérez,
  • Inmaculada Sánchez-Machín,
  • Fernando Pineda and
  • Paloma Poza-Guedes
Allergies2025, 5(1), 2;https://doi.org/10.3390/allergies5010002

10 January 2025

Seafood is a crucial source of nutrients, with global consumption steadily increasing. Among seafood-related allergies, shellfish are a significant cause of food allergy and anaphylaxis worldwide, affecting approximately 0.5–2.5% of the general...

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  • Article
  • Open Access
4,236 Views
12 Pages
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Analysis of Viability as Readout of Lymphocyte Transformation Test in Drug Hypersensitivity Diagnostics

  • András Gyovai,
  • Gabriella Metzler,
  • Krisztián Papp and
  • József Prechl
Allergies2025, 5(1), 1;https://doi.org/10.3390/allergies5010001

9 January 2025

In vitro tests of cellular activity form part of the diagnostic algorithm of drug hypersensitivity reactions. Because of the wide range of pharmacological mechanisms, clinical symptoms, genetic components, and laboratory tests involved, it is importa...

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Allergies - ISSN 2313-5786
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