Genetic Transformation in Cryptococcus Species
Department of Microbiology, Immunology, and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA
J. Fungi 2021, 7(1), 56; https://doi.org/10.3390/jof7010056
Submission received: 28 December 2020
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Revised: 11 January 2021
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Accepted: 13 January 2021
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Published: 15 January 2021
(This article belongs to the Special Issue Molecular and Genetic Tools for Studying Cryptococcus spp.)
Abstract
Genetic transformation plays an imperative role in our understanding of the biology in unicellular yeasts and filamentous fungi, such as Saccharomyces cerevisiae, Aspergillus nidulans, Cryphonectria parasitica, and Magnaporthe oryzae. It also helps to understand the virulence and drug resistance mechanisms of the pathogenic fungus Cryptococcus that causes cryptococcosis in health and immunocompromised individuals. Since the first attempt at DNA transformation in this fungus by Edman in 1992, various methods and techniques have been developed to introduce DNA into this organism and improve the efficiency of homology-mediated gene disruption. There have been many excellent summaries or reviews covering the subject. Here we highlight some of the significant achievements and additional refinements in the genetic transformation of Cryptococcus species.
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MDPI and ACS Style
Wang, P. Genetic Transformation in Cryptococcus Species. J. Fungi 2021, 7, 56. https://doi.org/10.3390/jof7010056
AMA Style
Wang P. Genetic Transformation in Cryptococcus Species. Journal of Fungi. 2021; 7(1):56. https://doi.org/10.3390/jof7010056
Chicago/Turabian StyleWang, Ping. 2021. "Genetic Transformation in Cryptococcus Species" Journal of Fungi 7, no. 1: 56. https://doi.org/10.3390/jof7010056
APA StyleWang, P. (2021). Genetic Transformation in Cryptococcus Species. Journal of Fungi, 7(1), 56. https://doi.org/10.3390/jof7010056
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