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Journal of Cardiovascular Development and Disease, Volume 9, Issue 3

March 2022 - 26 articles

Cover Story: Adult mammalian cardiomyocytes demonstrate scarce cycling and even lower proliferation rates in response to injury. Signals that enhance cardiomyocyte proliferation after injury will be groundbreaking, address unmet clinical needs, and represent new strategies to treat cardiovascular diseases. In vivo methods to monitor cardiomyocyte proliferation are critical to addressing this challenge. Fortunately, advances in transgenic approaches provide sophisticated techniques to quantify cardiomyocyte cycling and proliferation. This review will summarize the state-of-the-art transgenic mice label “Actively cycling” and “Previously cycled” cardiomyocytes and discuss how these powerful methods can contribute to regenerative cardiovascular medicine. View this paper
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Articles (26)

  • Review
  • Open Access
21 Citations
4,355 Views
13 Pages

Sex-Related Effects on Cardiac Development and Disease

  • Georgios Siokatas,
  • Ioanna Papatheodorou,
  • Angeliki Daiou,
  • Antigone Lazou,
  • Konstantinos E. Hatzistergos and
  • Georgios Kararigas

Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality. Interestingly, male and female patients with CVD exhibit distinct epidemiological and pathophysiological characteristics, implying a potentially important role for primar...

  • Article
  • Open Access
11 Citations
3,234 Views
12 Pages

Comparison of the Mid-Term Outcomes of Robotic Magnetic Navigation-Guided Radiofrequency Ablation versus Cryoballoon Ablation for Persistent Atrial Fibrillation

  • Xiang Li,
  • Yangyang Bao,
  • Kangni Jia,
  • Ning Zhang,
  • Changjian Lin,
  • Yue Wei,
  • Yun Xie,
  • Qingzhi Luo,
  • Tianyou Ling and
  • Kang Chen
  • + 3 authors

Introduction: Currently, numerous ablation techniques are available for atrial fibrillation (AF), in addition to manual radio frequency ablation. The aim of this prospective, non-randomized concurrent controlled trial was to compare the mid-term effi...

  • Review
  • Open Access
10 Citations
5,060 Views
9 Pages

Screening for Cardiovascular Disease in Pregnancy: Is There a Need?

  • Melissa E. Chambers,
  • Madushka Y. De Zoysa and
  • Afshan B. Hameed

Maternal mortality in the United States has been on the rise. Every year, about 700 women die from pregnancy-related complications. Cardiovascular disease (CVD) accounts for a large majority of pregnancy-related deaths driven by the lack of recogniti...

  • Review
  • Open Access
20 Citations
6,748 Views
14 Pages

Exercise Stress Echocardiography in the Diagnostic Evaluation of Heart Failure with Preserved Ejection Fraction

  • Tomonari Harada,
  • Kazuki Kagami,
  • Toshimitsu Kato,
  • Hideki Ishii and
  • Masaru Obokata

More than half of patients with heart failure have a preserved ejection fraction (HFpEF). The prevalence of HFpEF has been increasing worldwide and is expected to increase further, making it an important health-care problem. The diagnosis of HFpEF is...

  • Article
  • Open Access
32 Citations
7,302 Views
17 Pages

Transfer Learning Models for Detecting Six Categories of Phonocardiogram Recordings

  • Miao Wang,
  • Binbin Guo,
  • Yating Hu,
  • Zehang Zhao,
  • Chengyu Liu and
  • Hong Tang

Background and aims: Auscultation is a cheap and fundamental technique for detecting cardiovascular disease effectively. Doctors’ abilities in auscultation are varied. Sometimes, there may be cases of misdiagnosis, even when auscultation is per...

  • Article
  • Open Access
8 Citations
4,423 Views
11 Pages

The Effect of a Single Bout of Resistance Exercise with Blood Flow Restriction on Arterial Stiffness in Older People with Slow Gait Speed: A Pilot Randomized Study

  • Samuel Amorim,
  • Alexandra Passos Gaspar,
  • Hans Degens,
  • Maysa Seabra Cendoroglo,
  • Fábio Gazelato de Mello Franco,
  • Raphael Mendes Ritti-Dias,
  • Gabriel Grizzo Cucato,
  • Nicholas Rolnick and
  • Luciana Diniz Nagem Janot de Matos

Purpose: Low-intensity resistance exercise with moderate blood-flow restriction (LIRE-BFR) is a new trending form of exercises worldwide. The purpose of this study was to compare the acute effect of a single bout of traditional resistance exercise (T...

  • Article
  • Open Access
5 Citations
4,041 Views
10 Pages

Gender Particularities and Prevalence of Atypical Clinical Presentation in Non-ST Elevation Acute Coronary Syndrome

  • Mihai Octavian Negrea,
  • Dumitru Zdrenghea,
  • Minodora Teodoru,
  • Bogdan Neamțu,
  • Călin Remus Cipăian and
  • Dana Pop

Clinical presentation is one of the factors that can influence how quickly a patient with an acute coronary syndrome is treated, particularly if it is atypical. The purposes of this study are to explore gender-related differences in patients presenti...

  • Case Report
  • Open Access
5 Citations
3,336 Views
8 Pages

Open Coronary Endarterectomy of Left Anterior Descending Artery—Case Report and Review of Literature

  • Mircea Robu,
  • Diana Romina Marian,
  • Ecaterina Lazăr,
  • Răzvan Radu,
  • Cristian Boroș,
  • Andra Sibișan,
  • Cristian Voica,
  • Marian Broască,
  • Daniela Gheorghiță and
  • Horațiu Moldovan
  • + 1 author

Coronary endarterectomy (CE) emerged as a necessity to achieve complete surgical myocardial revascularization in patients with diffusely diseased coronary arteries and it also serves as aid to coronary bypass grafting (CABG). The safety and postopera...

  • Article
  • Open Access
15 Citations
8,301 Views
13 Pages

Coronary Artery Disease in Very Young Patients: Analysis of Risk Factors and Long-Term Follow-Up

  • Pablo Juan-Salvadores,
  • Víctor Alfonso Jiménez Díaz,
  • Cristina Iglesia Carreño,
  • Alba Guitián González,
  • Cesar Veiga,
  • Cristina Martínez Reglero,
  • José Antonio Baz Alonso,
  • Francisco Caamaño Isorna and
  • Andrés Iñiguez Romo

Coronary artery disease (CAD) is a common chronic condition in the elderly. However, the earlier CAD begins, the stronger its impact on lifestyle and costs of health and social care. The present study analyzes clinical and angiographic features and t...

  • Case Report
  • Open Access
10 Citations
3,536 Views
6 Pages

Salvage of Cardiac Implantable Electronic Device Pocket Infection with Skin Erosion in Frail 92-Year-Old

  • Marzia Giaccardi,
  • Benito Baldauf,
  • Ernest W. Lau,
  • Stefan Borov and
  • Hendrik Bonnemeier

We reported the novel use of a taurolidine-containing antimicrobial solution in the successful salvage of a partially exposed and polymicrobially infected cardiac implantable electronic device pulse generator in a frail patient unfit for lead extract...

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J. Cardiovasc. Dev. Dis. - ISSN 2308-3425