Next Article in Journal
Current Status and Major Challenges to the Safety and Efficacy Presented by Chinese Herbal Medicine
Previous Article in Journal
Systematic Use of Music as an Environmental Intervention and Quality of Care in Nursing Homes: A Qualitative Case Study in Norway
Previous Article in Special Issue
Internet Mindfulness Meditation Intervention (IMMI) Improves Depression Symptoms in Older Adults
Article Menu
Issue 1 (March) cover image

Export Article

Open AccessProtocol

Effects of Qigong Exercise on Non-Motor Symptoms and Inflammatory Status in Parkinson’s Disease: A Protocol for a Randomized Controlled Trial

1
Department of Physical Therapy and Rehabilitation Science, School of Health Professions, University of Kansas Medical Center; 3901 Rainbow Blvd., MailStop 2002, Kansas City, KS 66160, USA
2
Department of Neurology, School of Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd., MailStop 2012, Kansas City, KS 66160, USA
3
Department of Preventive Medicine and Public Health, School of Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd., MailStop 1008, Kansas City, KS 66160, USA
*
Author to whom correspondence should be addressed.
Medicines 2019, 6(1), 13; https://doi.org/10.3390/medicines6010013
Received: 2 December 2018 / Revised: 4 January 2019 / Accepted: 16 January 2019 / Published: 18 January 2019
(This article belongs to the Special Issue Mind-body Medicine Approaches)
  |  
PDF [592 KB, uploaded 31 January 2019]
  |  

Abstract

Background: Non-motor symptoms such as sleep disturbance, cognitive decline, fatigue, anxiety, and depression in Parkinson’s disease (PD) impact quality of life. Increased levels of pro-inflammatory cytokines in individuals with PD have been reported, which may contribute to non-motor symptoms. A mind-body exercise, Qigong, has demonstrated benefits across different medical conditions. However, a lack of evidence causes clinicians and patients to be uncertain about the effects of Qigong in individuals with PD. This study will examine the effects of Qigong on non-motor symptoms and inflammatory status in individuals with PD. Methods: Sixty individuals with PD will be recruited. Qigong and sham Qigong group (n = 30 for each) will receive a 12-week intervention. Participants will practice their assigned exercise at home (2×/day) and attend routinely group exercise meetings. Results: Clinical questionnaires and neuropsychological tests will measure non-motor symptoms including sleep quality (primary outcome). Biomarker assays will measure inflammatory status. A two-way mixed-design analysis of variance (ANOVA) will be utilized. Conclusions: This study may generate evidence for the benefits of Qigong on non-motor symptoms of PD and the effect on inflammatory status. Findings may lead to the development of a novel, safe, and cost-effective rehabilitation approach for individuals with PD. View Full-Text
Keywords: Parkinson’s disease; Qigong; mind-body therapies; cytokines; randomized controlled trial Parkinson’s disease; Qigong; mind-body therapies; cytokines; randomized controlled trial
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Moon, S.; Sarmento, C.V.M.; Smirnova, I.V.; Colgrove, Y.; Lyons, K.E.; Lai, S.M.; Liu, W. Effects of Qigong Exercise on Non-Motor Symptoms and Inflammatory Status in Parkinson’s Disease: A Protocol for a Randomized Controlled Trial. Medicines 2019, 6, 13.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Medicines EISSN 2305-6320 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top