Processes, Volume 1, Issue 3

Recent literature suggests that mesenchymal stem/stromal cells (MSC) could be used as Trojan Horses to deliver “death-signals” to cancer cells. Herein, we describe the development of a novel multichannel cell migration device, and use it to investiga...

The judicious use of buffering capacity is important in the development of future continuous pharmaceutical manufacturing processes. The potential benefits are investigated of using optimal-averaging level control for tanks that have buffering capaci...

This paper presents a study based on real plant data collected from chiller plants at the University of Texas at Austin. It highlights the advantages of operating the cooling processes based on an optimal strategy. A multi-component model is develope...

This work describes how the design and operation parameters of the Multi-Stage Flash (MSF) desalination process are optimised when the process is subject to variation in seawater temperature, fouling and freshwater demand throughout the day. A simple...

Chinese hamster ovary (CHO) cells are a source of multi-ton quantities of protein pharmaceuticals. They are, however, immortalized cells, characterized by a high degree of genetic and phenotypic diversity. As is known for any biological system, this...

Composite membranes with stimuli-responsive properties can be made by coating a thermo-responsive hydrogel onto a micro- or macroporous support. These hydrogels undergo a temperature induced volume-phase transition, which contributes towards the comp...

The nonlinear behavior of metabolic systems can arise from at least two different sources. One comes from the nonlinear kinetics of chemical reactions in metabolism and the other from nonlinearity associated with regulatory processes. Consequently, o...