Regional Splanchnic Oxygenation during Continuous versus Bolus Feeding among Stable Preterm Infants
Abstract
:1. Introduction
2. Materials and Methods
2.1. Study Protocol
2.2. Statistical Analysis
3. Results
4. Discussion
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Schanler, R.J.; Shulman, R.J.; Lau, C. Feeding strategies for premature infants: Beneficial outcomes of feeding fortified human milk versus preterm formula. Pediatrics 1999, 103, 1150–1157. [Google Scholar] [CrossRef] [PubMed]
- Hay, W.W., Jr. Strategies for feeding the preterm infant. Neonatology 2008, 94, 245–254. [Google Scholar] [PubMed] [Green Version]
- Ehrenkranz, R.A.; Das, A.; Wrage, L.A. Early nutrition mediates the influence of severity of illness on extremely LBW infants. Pediatr. Res. 2011, 69, 522–529. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Morgan, J.; Young, L.; McGuire, W. Delayed introduction of progressive enteral feeds to prevent necrotizing enterocolitis in very low birth weight infants. Cochrane Database Syst. Rev. 2011, 16, CD001970. [Google Scholar]
- Premji, S.S.; Chessell, L. Continuous nasogastric milk feeding versus intermittent bolus milk feeding for premature infants less than 1500 grams. Cochrane Database Syst. Rev. 2011, 11, CD001819. [Google Scholar] [CrossRef]
- Fang, S.; Kempley, S.T.; Gamsu, H.R. Prediction of early tolerance to enteral feeding in preterm infants by measurement of superior mesenteric artery blood flow velocity. Arch. Dis. Child. Fetal Neonatal Ed. 2001, 85, F42–F45. [Google Scholar] [CrossRef] [Green Version]
- Pezzati, M.; Dani, C.; Tronchin, M.; Fillipi, L.; Rossi, S.; Rubaltelli, F.F. Prediction of early tolerance to enteral feeding by measurement of superior mesenteric artery blood flow velocity: Appropriate- versus small-for-gestational-age preterm infants. Acta Paediatr. 2004, 93, 797–802. [Google Scholar] [CrossRef]
- Cortez, J.; Gupta, M.; Amaram, A.; Pizzino, J.; Sawhney, M.; Sood, B.G. Noninvasive evaluation of splanchnic tissue oxygenation using near-infrared spectroscopy in preterm neonates. J. Matern. Fetal Neonatal Med. 2011, 24, 574–582. [Google Scholar] [CrossRef]
- Dave, V.; Brion, L.P.; Campbell, D.E.; Scheiner, M.; Raab, C.; Nafday, S.M. Splanchnic tissue oxygenation, but not brain tissue oxygenation, increases after feeds in stable preterm neonates tolerating full bolus orogastric feeding. J. Perinatol. 2009, 29, 213–218. [Google Scholar] [CrossRef] [Green Version]
- Wahr, J.A.; Tremper, K.K.; Samra, S.; Delpy, D.T. Near infrared spectroscopy: Theory and applications. J. Cardiothorac. Vasc. Anesth. 1996, 10, 406–418. [Google Scholar] [CrossRef]
- Gillam-Krakauer, M.; Cochran, C.M.; Slaughter, J.C.; Polavarapu, S.; McElroy, S.J.; Hernanz-Schulman, M.; Engelhardt, B. Correlation of abdominal rSO2 with superior mesenteric artery velocities in preterm infants. J. Perinatol. 2013, 33, 609–612. [Google Scholar] [CrossRef] [Green Version]
- Dani, C.; Corsini, I.; Generoso, M.; Gozzini, E.; Bianconi, T.; Pratesi, S. Splanchnic Tissue Oxygenation for Predicting Feeding Tolerance in Preterm Infants. J. Parenter. Enteral Nutr. 2015, 39, 935–940. [Google Scholar] [CrossRef]
- Corvaglia, L.; Martini, S.; Battistini, B.; Rucci, P.; Faldella, G.; Aceti, A. Splanchnic oxygenation at first enteral feeding in preterm infants: Correlation with feeding tolerance. J. Pediatr. Gastroenterol. Nutr. 2017, 64, 550–554. [Google Scholar] [CrossRef]
- Dani, C.; Pratesi, S.; Barp, J.; Bertini, G.; Gozzini, E.; Mele, L.; Parrini, L. Near-infrared spectroscopy measurements of splanchnic tissue oxygenation during continuous versus intermittent feeding method in preterm infants. J. Pediatr. Gastroenterol. Nutr. 2013, 56, 652–656. [Google Scholar] [CrossRef]
- Corvaglia, L.; Martini, S.; Battistini, B.; Rucci, P.; Aceti, A.; Faldella, G. Bolus vs. continuous feeding: Effects on splanchnic and cerebral tissue oxygenation in healthy preterm infants. Pediatr. Res. 2014, 76, 81–85. [Google Scholar] [CrossRef]
- Leidig EOzkan, H.; Oren, H.; Erdag, N.; Cevik, N. Breast milk versus infant formulas: Effects on intestinal blood flow in neonates. Indian J. Pediatr. 1994, 61, 703–709. [Google Scholar]
- Coombs, R.C.; Morgan, M.E.; Durbin, G.M.; Booth, I.W.; McNeish, A.S. Doppler assessment of human neonatal gut blood flow velocities: Postnatal adaptation and response to feeds. J. Pediatr. Gastroenterol. Nutr. 1992, 15, 6–12. [Google Scholar] [CrossRef]
- Lane, A.J.P.; Coombs, R.C.; Evans, D.H.; Levin, R.J. Effect of feed interval and feed type on splanchnic hemodynamics. Arch. Dis. Child. Fetal Neonatal Ed. 1998, 79, F49–F53. [Google Scholar] [CrossRef]
- Demirel, G.; Oguz, S.; Celik, I.H.; Erdeve, O.; Dilmen, U. Cerebral and mesenteric tissue oxygenation by positional changes in very low birth weight premature infants. Ear. Hum. Dev. 2012, 88, 409–411. [Google Scholar] [CrossRef]
- Aynsley-Green, A.; Adrian, T.E.; Bloom, S.R. Feeding and the development of enteroinsular hormone secretion in the preterm infant: Effects of continuous gastric infusions of human milk compared with intermittent boluses. Acta Paediat. Scand. 1982, 71, 379–383. [Google Scholar] [CrossRef]
- Havranek, T.; Miladinovic, B.; Wadhawan, R.; Carver, J.D. Factors that affect the postnatal increase in superior mesenteric artery blood flow velocity in very low birth weight preterm infants. J. Perinat. Med. 2012, 40, 565–570. [Google Scholar] [CrossRef]
- Poets, C.F.; Langner, M.U.; Bohnhorst, B. Effects of bottle feeding and two different methods of gavage feeding on oxygenation and breathing patterns in preterm infants. Acta Paediatr. 1997, 86, 419–423. [Google Scholar] [CrossRef]
- Toce, S.S.; Keenan, W.J.; Homan, S.M. Enteral feeding in very-low-birth-weight infants. A comparison of two nasogastric methods. Am. J. Dis. Child. 1987, 141, 439–444. [Google Scholar] [CrossRef]
- Akintorin, S.M.; Kamat, M.; Pildes, R.S. A prospective randomized trial of feeding methods in very low birth weight infants. Pediatrics 1997, 100, E4. [Google Scholar] [CrossRef] [Green Version]
Characteristic | Result | |
---|---|---|
Gestational age at birth, weeks | 28.81 ± 1.63 | |
Birth weight, grams * | 1270 ± 330 | |
Male sex ** | 12 (57) | |
Cesarean section delivery ** | 15 (61) | |
Age at study, days * | 32.05 ± 13.59 | |
Gestational age at study, weeks | 33.29 ± 1.38 | |
Weight at study entry, grams * | 1730 ± 310 | |
Feeding volume at study entry, ml/kg/day * | 157.71 ± 7 | |
Gestational age at study entry, weeks * | 30.61 ± 1.24 | |
Type of feeding ** | Fortified human milk | 10 (48) |
Preterm formula | 4 (19) | |
Mix | 7 (33) |
Mean ± SD | Period 0 | Period 1 | Period 2 | Period 3 | * p |
---|---|---|---|---|---|
rSO2S | 58.99 ± 10.71 | 58.78 ± 9.07 | 60.32 ± 10.02 | 55.60 ± 12.41 | 0.025 |
SaO2 | 97.43 ± 2.35 | 96.81 ± 2.50 | 97.29 ± 2.61 | 97.71 ± 1.73 | 0.055 |
FOES | 0.39 ± 0.11 | 0.39 ± 0.09 | 0.40 ± 0.12 | 0.44 ± 0.11 | 0.129 |
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Sirota, G.L.; Litmanovitz, I.; Vider, C.; Arnon, S.; Moore, S.S.; Grinblatt, E.; Levkovitz, O.; Bauer Rusek, S. Regional Splanchnic Oxygenation during Continuous versus Bolus Feeding among Stable Preterm Infants. Children 2022, 9, 691. https://doi.org/10.3390/children9050691
Sirota GL, Litmanovitz I, Vider C, Arnon S, Moore SS, Grinblatt E, Levkovitz O, Bauer Rusek S. Regional Splanchnic Oxygenation during Continuous versus Bolus Feeding among Stable Preterm Infants. Children. 2022; 9(5):691. https://doi.org/10.3390/children9050691
Chicago/Turabian StyleSirota, Gisela Laura, Ita Litmanovitz, Carmel Vider, Shmuel Arnon, Shiran Sara Moore, Eynit Grinblatt, Orly Levkovitz, and Sofia Bauer Rusek. 2022. "Regional Splanchnic Oxygenation during Continuous versus Bolus Feeding among Stable Preterm Infants" Children 9, no. 5: 691. https://doi.org/10.3390/children9050691
APA StyleSirota, G. L., Litmanovitz, I., Vider, C., Arnon, S., Moore, S. S., Grinblatt, E., Levkovitz, O., & Bauer Rusek, S. (2022). Regional Splanchnic Oxygenation during Continuous versus Bolus Feeding among Stable Preterm Infants. Children, 9(5), 691. https://doi.org/10.3390/children9050691