Children 2017, 4(12), 113; https://doi.org/10.3390/children4120113
A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review
Pablo Manresa 1,*
, Fabián Tarín 1, María Niveiro 2, María Tasso 3, Olga Alda 1, Francisco López 1, Héctor Sarmiento 1, José J. Verdú 1, Francisco De Paz 1, Silvia López 3, María Del Cañizo 3, Esperanza Such 4, Eva Barragán 4 and Fernanda Martirena 5
, Fabián Tarín 1, María Niveiro 2, María Tasso 3, Olga Alda 1, Francisco López 1, Héctor Sarmiento 1, José J. Verdú 1, Francisco De Paz 1, Silvia López 3, María Del Cañizo 3, Esperanza Such 4, Eva Barragán 4 and Fernanda Martirena 51
Department of Hematology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
2
Department of Anatomic Pathology, Hospital General Universitario de Alicante, 03010 Alicante, Spain
3
Department of Pediatrics, Hospital General Universitario de Alicante, 03010 Alicante, Spain
4
Department of Hematology, Hospital Universitario La Fe de Valencia, 46009 Valencia, Spain
5
Department of Hematology, Hospital de Elda, 03600 Elda, Alicante, Spain
*
Author to whom correspondence should be addressed.
Received: 4 November 2017 / Revised: 16 December 2017 / Accepted: 19 December 2017 / Published: 20 December 2017
(This article belongs to the Section Oncology and Hematology)
Abstract
We describe an exceptional case of erythroid sarcoma in a pediatric patient as a growing orbital mass with no evidence of morphologic bone marrow involvement, who was finally diagnosed of pure erythroid sarcoma based on histopathology and flow cytometry criteria. We discuss the contribution of standardized eight-color flow cytometry as a rapid and reliable diagnostic method. The use of normal bone marrow databases allowed us to identify small aberrant populations in bone marrow and later confirm the diagnosis in the neoplastic tissue. View Full-TextKeywords:
red blood cell disorders; leukemias; acute; hematology; immunophenotype; sarcomas; including soft tissue; non-rhabdoid
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Manresa, P.; Tarín, F.; Niveiro, M.; Tasso, M.; Alda, O.; López, F.; Sarmiento, H.; Verdú, J.J.; De Paz, F.; López, S.; Del Cañizo, M.; Such, E.; Barragán, E.; Martirena, F. A Rare Case of Pure Erythroid Sarcoma in a Pediatric Patient: Case Report and Literature Review. Children 2017, 4, 113.
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