Structural Insights into Substrate Recognition and Processing by the 20S Proteasome
Abstract
:1. Introduction
2. Substrate Degradation Signals for 20S Proteasomes
3. Structural Precision of 20S Proteasomes for Substrate Degradation
4. The Functional Cycle of 20S Proteasomes
4.1. Substrate Accepting State (SA)
4.2. Substrate Binding State (SB)
4.3. Substrate Processing State (SP)
5. Peptide Generation by the 20S Proteasome
6. Concluding Remarks
Author Contributions
Funding
Conflicts of Interest
References
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Sahu, I.; Glickman, M.H. Structural Insights into Substrate Recognition and Processing by the 20S Proteasome. Biomolecules 2021, 11, 148. https://doi.org/10.3390/biom11020148
Sahu I, Glickman MH. Structural Insights into Substrate Recognition and Processing by the 20S Proteasome. Biomolecules. 2021; 11(2):148. https://doi.org/10.3390/biom11020148
Chicago/Turabian StyleSahu, Indrajit, and Michael H. Glickman. 2021. "Structural Insights into Substrate Recognition and Processing by the 20S Proteasome" Biomolecules 11, no. 2: 148. https://doi.org/10.3390/biom11020148