Oxylipin Response to Acute and Chronic Exercise: A Systematic Review
1
Physical Therapy Department, Federal University of São Carlos, São Carlos, SP 13565-905, Brazil
2
North Carolina Research Campus, Appalachian State University, Kannapolis, NC 28081, USA
*
Author to whom correspondence should be addressed.
Metabolites 2020, 10(6), 264; https://doi.org/10.3390/metabo10060264
Received: 28 May 2020
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Revised: 18 June 2020
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Accepted: 19 June 2020
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Published: 25 June 2020
(This article belongs to the Special Issue Fatty Acid Metabolism)
Oxylipins are oxidized compounds of polyunsaturated fatty acids that play important roles in the body. Recently, metabololipidomic-based studies using advanced mass spectrometry have measured the oxylipins generated during acute and chronic physical exercise and described the related physiological effects. The objective of this systematic review was to provide a panel of the primary exercise-related oxylipins and their respective functions in healthy individuals. Searches were performed in five databases (Cochrane, PubMed, Science Direct, Scopus and Web of Science) using combinations of the Medical Subject Headings (MeSH) terms: “Humans”, “Exercise”, “Physical Activity”, “Sports”, “Oxylipins”, and “Lipid Mediators”. An adapted scoring system created in a previous study from our group was used to rate the quality of the studies. Nine studies were included after examining 1749 documents. Seven studies focused on the acute effect of physical exercise while two studies determined the effects of exercise training on the oxylipin profile. Numerous oxylipins are mobilized during intensive and prolonged exercise, with most related to the inflammatory process, immune function, tissue repair, cardiovascular and renal functions, and oxidative stress.
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Keywords:
inflammation; lipid mediators; lipidomics; metabolites; metabolomics; physical exercise
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MDPI and ACS Style
Signini, É.F.; Nieman, D.C.; Silva, C.D.; Sakaguchi, C.A.; Catai, A.M. Oxylipin Response to Acute and Chronic Exercise: A Systematic Review. Metabolites 2020, 10, 264. https://doi.org/10.3390/metabo10060264
AMA Style
Signini ÉF, Nieman DC, Silva CD, Sakaguchi CA, Catai AM. Oxylipin Response to Acute and Chronic Exercise: A Systematic Review. Metabolites. 2020; 10(6):264. https://doi.org/10.3390/metabo10060264
Chicago/Turabian StyleSignini, Étore F., David C. Nieman, Claudio D. Silva, Camila A. Sakaguchi, and Aparecida M. Catai. 2020. "Oxylipin Response to Acute and Chronic Exercise: A Systematic Review" Metabolites 10, no. 6: 264. https://doi.org/10.3390/metabo10060264
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