Identification of LL-37 as a Molecular Target for Boswellic Acids

A. HENKEL; L. TAUSCH; O. WERZ

doi:10.3797/scipharm.oephg.21.PO-39

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Abstract

16 April 2009

Identification of LL-37 as a Molecular Target for Boswellic Acids

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Pharmaceutical Institute, Eberhard Karls University, Auf der Morgenstelle 8, 72076, Tübingen, Germany

Institute of Pharmaceutical Chemistry, Goethe University, Max-von-Laue-Str. 9, 60438, Frankfurt, Germany

Author to whom correspondence should be addressed.

Sci. Pharm.2009, 77(7), 238;https://doi.org/10.3797/scipharm.oephg.21.PO-39

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Gum resin extracts of Boswellia serrata have been traditionally applied in folk medicine for the treatment of various inflammatory diseases. Analyses of these extracts identified a group of pentacyclic triterpenes, the boswellic acids (BAs), as active principles that might be responsible for some of the observed anti-inflammatory effects.[...]

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