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Sci. Pharm.
Volume 77
Issue 7
10.3797/scipharm.oephg.21.PO-19
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Scientia Pharmaceutica is published by MDPI from Volume 84 Issue 3 (2016). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Austrian Pharmaceutical Society (Österreichische Pharmazeutische Gesellschaft, ÖPhG).
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Abstract

Functionability of NMDA-Receptors in an in vitro model of the Blood-Brain-Barrier

by
M. FREIDL
1,
W. NEUHAUS
1,
M. WIRTH
3,
F. GABOR
3 and
C. R. NOE
2,*
1
Department of Medicinal Chemistry, University of Vienna, Althanstraße 14, 1090 Vienna, Austria
2
PharmaCon GmbH, Riglergasse 4/5, 1180 Vienna, Austria
3
Department of Pharmaceutical Technology and Biopharmaceutics, University of Vienna, Althanstraße 14, 1090 Vienna, Austria
*
Author to whom correspondence should be addressed.
Sci. Pharm. 2009, 77(7), 218; https://doi.org/10.3797/scipharm.oephg.21.PO-19
Submission received: 16 April 2009 / Accepted: 16 April 2009 / Published: 16 April 2009
Versions Notes

Abstract

A diversity of disease processes and conditions such as Alzheimer´s disease, schizophrenia, epilepsy and stroke – although they are caused by different mechanism – share one common target: the NMDA-receptor [1]. Recent studies reported the presence and the participation of this glutamate-gated ion-channel in major regulatory mechanisms at the blood-brain barrier (BBB). In order to show the functionability of this receptor and his effects on the BBB, we used an in vitro model based on human cell line ECV304 [2].

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MDPI and ACS Style

FREIDL, M.; NEUHAUS, W.; WIRTH, M.; GABOR, F.; NOE, C.R. Functionability of NMDA-Receptors in an in vitro model of the Blood-Brain-Barrier. Sci. Pharm. 2009, 77, 218. https://doi.org/10.3797/scipharm.oephg.21.PO-19

AMA Style

FREIDL M, NEUHAUS W, WIRTH M, GABOR F, NOE CR. Functionability of NMDA-Receptors in an in vitro model of the Blood-Brain-Barrier. Scientia Pharmaceutica. 2009; 77(Posters (PO)):218. https://doi.org/10.3797/scipharm.oephg.21.PO-19

Chicago/Turabian Style

FREIDL, M., W. NEUHAUS, M. WIRTH, F. GABOR, and C. R. NOE. 2009. "Functionability of NMDA-Receptors in an in vitro model of the Blood-Brain-Barrier" Scientia Pharmaceutica 77, Posters (PO): 218. https://doi.org/10.3797/scipharm.oephg.21.PO-19

APA Style

FREIDL, M., NEUHAUS, W., WIRTH, M., GABOR, F., & NOE, C. R. (2009). Functionability of NMDA-Receptors in an in vitro model of the Blood-Brain-Barrier. Scientia Pharmaceutica, 77(Posters (PO)), 218. https://doi.org/10.3797/scipharm.oephg.21.PO-19

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