Pyrrolizidine Alkaloids from Ligularia sibirica Cass. and Tephroseris integrifolia L.

Helmut Wiedenfeld; S. Narantuya; M. Dumaa; A. Monhbaatar

doi:10.3797/scipharm.aut-03-14

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Article

28 May 2003

Pyrrolizidine Alkaloids from Ligularia sibirica Cass. and Tephroseris integrifolia L.

and

PharmazeutischesIn stitut der Universitat, An der Immenburg 4, D-53121 Bonn, Germany

National Medical University of Mongolia, Choidog St. 3, Ulaanbaatar 48/111, Mongolia

Institute of Chemistry and Chemical Technology, Mongolian Academy of Science, Ulaanbaatar-5 1, Mongolia

Author to whom correspondence should be addressed.

Sci. Pharm.2003, 71(2), 129-132;https://doi.org/10.3797/scipharm.aut-03-14

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Abstract

Tussilagine, isotussilagine, neo-tussilagine and neo-isotussilagine were isolated from Ligularia sibirica whereas Tephroseris integrifolia was found to contain senkirkine, otosenine, hydroxysenkirkine and 07-angeloylheliotridine. The structures were determined using spectroscopical methods (GC-MS; NMR).

Keywords:

Ligularia sibirica; Tephroseris integrifolia; pyrrolizidine alkaloids

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