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Diseases, Volume 8, Issue 1

March 2020 - 7 articles

Cover Story: Rabies ranked 12th on the WHO list of major killer diseases, and it is under the OIE category of multiple species diseases, infections, and infestations. Currently, it remains an ongoing threat to human populations and animals in many parts of the world. The etiologic agent of this disease is the rabies virus, belonging to the genus Lyssavirus and family Rhabdoviridae. Rabies is one of the most serious zoonotic diseases. Once clinical signs develop, the disease results in almost 100% fatality. Next to Asia, Africa is the continent most affected by rabies, with an estimated 24,000 (44%) of the 55,000 annual rabies deaths worldwide, which has been estimated to increase to 59,000 annual rabies deaths after 10 years. Domestic dogs are considered to be the main sources (>90%) of human rabies in Africa and more than 88% of the exposure cases in Ethiopia were due to dog bites. In the study area, the community believes in the use of traditional practices as a control m
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Articles (7)

  • Article
  • Open Access
18 Citations
5,523 Views
10 Pages

Chronic stress and cardiovascular disease risk were explored in a predominately middle-aged adult population exposed to elevated lead levels in this cross-sectional study using data from the National Health and Nutrition Examination Survey (NHANES) f...

  • Article
  • Open Access
17 Citations
7,202 Views
11 Pages

Are Steroid Hormones Dysregulated in Autistic Girls?

  • Benedikt Andreas Gasser,
  • Johann Kurz,
  • Bernhard Dick and
  • Markus Georg Mohaupt

Evidence of altered cholesterol and steroid hormones in autism is increasing. However, as boys are more often affected, evidence mainly relates to autistic males, whereas evidence for affected autistic girls is sparse. Therefore, a comprehensive gas...

  • Article
  • Open Access
26 Citations
7,081 Views
13 Pages

24 February 2020

A cross-sectional study was conducted from February 2017 to April 2017 to assess knowledge, attitude and practices of the community towards rabies in south Gondar zone, Ethiopia. A structured closed ended questionnaire was used to collect the data th...

  • Article
  • Open Access
6 Citations
4,143 Views
12 Pages

One Single Nucleotide Polymorphism of the TRPM2 Channel Gene Identified as a Risk Factor in Bipolar Disorder Associates With Autism Spectrum Disorder in a Japanese Population

  • Naila Al Mahmuda,
  • Shigeru Yokoyama,
  • Toshio Munesue,
  • Kenshi Hayashi,
  • Kunimasa Yagi,
  • Chiharu Tsuji and
  • Haruhiro Higashida

7 February 2020

The transient receptor potential melastatin 2 (TRPM2) is a non-specific cation channel, resulting in Ca2+ influx at warm temperatures from 34 °C to 47 °C, thus including the body temperature range in mammals. TRPM2 channels are activated by &...

  • Article
  • Open Access
3 Citations
4,009 Views
13 Pages

Genetic Analysis of Peroxisomal Genes Required for Longevity in a Yeast Model of Citrin Deficiency

  • Chalongchai Chalermwat,
  • Thitipa Thosapornvichai,
  • Laran T. Jensen and
  • Duangrurdee Wattanasirichaigoon

Citrin is a liver-specific mitochondrial aspartate–glutamate carrier encoded by SLC25A13. Citrin deficiency caused by SLC25A13 mutation results in carbohydrate toxicity, citrullinemia type II, and fatty liver diseases, the mechanisms of some of...

  • Article
  • Open Access
9 Citations
4,826 Views
10 Pages

“I Actually Don’t Know What HIV Is”: A Mixed Methods Analysis of College Students’ HIV Literacy

  • Robert M. Avina,
  • Mathew Mullen,
  • Salome Mshigeni and
  • Monideepa B. Becerra

Objective: Human immunodeficiency virus (HIV) remains a major public health issue with young adults facing a disproportionately higher rate of the burden. Our goal was to address the current literacy related to HIV, including biomedical prevention me...

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Diseases - ISSN 2079-9721