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A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects

1
Laboratory of Nano-Photonics and Biosensors, Institute of Electro-Optical Engineering, National Taiwan Normal University, Taipei 11677, Taiwan
2
Department of Electronics Engineering, State Polytechnic of Cilacap, Cilacap 53211, Indonesia
3
Department of Life Science, National Taiwan Normal University, Taipei 11677, Taiwan
*
Author to whom correspondence should be addressed.
Nanomaterials 2021, 11(1), 216; https://doi.org/10.3390/nano11010216
Received: 30 December 2020 / Revised: 7 January 2021 / Accepted: 12 January 2021 / Published: 15 January 2021
(This article belongs to the Special Issue Carbon-Based Nanocomposites for Biosensing Approaches)
The surface plasmon resonance (SPR) biosensor has become a powerful analytical tool for investigating biomolecular interactions. There are several methods to excite surface plasmon, such as coupling with prisms, fiber optics, grating, nanoparticles, etc. The challenge in developing this type of biosensor is to increase its sensitivity. In relation to this, graphene is one of the materials that is widely studied because of its unique properties. In several studies, this material has been proven theoretically and experimentally to increase the sensitivity of SPR. This paper discusses the current development of a graphene-based SPR biosensor for various excitation methods. The discussion begins with a discussion regarding the properties of graphene in general and its use in biosensors. Simulation and experimental results of several excitation methods are presented. Furthermore, the discussion regarding the SPR biosensor is expanded by providing a review regarding graphene-based Surface-Enhanced Raman Scattering (SERS) biosensor to provide an overview of the development of materials in the biosensor in the future. View Full-Text
Keywords: biosensors; surface plasmon resonance; graphene biosensors; surface plasmon resonance; graphene
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MDPI and ACS Style

Nurrohman, D.T.; Chiu, N.-F. A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects. Nanomaterials 2021, 11, 216. https://doi.org/10.3390/nano11010216

AMA Style

Nurrohman DT, Chiu N-F. A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects. Nanomaterials. 2021; 11(1):216. https://doi.org/10.3390/nano11010216

Chicago/Turabian Style

Nurrohman, Devi T.; Chiu, Nan-Fu. 2021. "A Review of Graphene-Based Surface Plasmon Resonance and Surface-Enhanced Raman Scattering Biosensors: Current Status and Future Prospects" Nanomaterials 11, no. 1: 216. https://doi.org/10.3390/nano11010216

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